Historic milestone: Man receives world's first gene-edited pig liver transplant
Representational image of doctors conducting a surgery.
A man with advanced liver cancer received the first liver transplantfrom a pig in history. The guy was given a liver transplant from a pig that had hadits genes altered, according to Chinese doctors.
This is beingconsidered a turning point in the xenotransplantation procedure, which involves transplanting animalorgans into humans. On May 24, Anhui Medical University's First Affiliated Hospital posted on WeChat that a 71-year-old man suffering from liver cancer had gotten the organ on May 17.
The patient "was able to walk freely, no hyper-acute or acute rejection reactions were found, the coagulation system was not impaired, and liver function had returned to normal," according to a statement from the university,reported by the South China Morning Post.
Ten gene modifications were included in the 514-gram liver of the pig to stop organ rejection and malfunction. After it was determined that the patient's left lobe of the liver was failing to function normally on its own and was not improving with conventional therapies, the patient had a liver transplant from a pig.
About 200 milliliters of golden bile are secreted daily from the transplanted pig liver, according to hospital head Sun Beicheng, as reported by People's Daily.
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The first gene-edited pig liver was transplanted into a patient who had experienced brain death in March by a Chinese team from Air Force Medical University, marking another significant surgical accomplishment.
Additionally in March, a US patient became the first person globally to receive a kidney transplant from a gene-modified pig—a technique that was previously limited to patients who were clinically dead.
Even though the patient passed away in May, Massachusetts General Hospital in Boston reported that the man's death was not related to the transplant.
(With inputs from agencies)