As many as 10 bombs were reported in and around the city in Nangarhar province. No group has claimed responsibility so far.
Jalalabad is the scene of frequent bomb attacks, and the surrounding terrain is home to both Taliban fighters and the Islamic State group's local affiliate.
Mayhem from Afghanistan's war continues to wreak havoc on Afghans every day, even though the US and the Taliban are in final negotiations for a deal that would see US troops begin to quit Afghanistan and could potentially lead to a reduction in violence.
'We will avenge the blood of our people, every drop of it,' Ashraf Ghani said.