First baby born through new egg-freezing technique in France
IVF
A woman in France has given birth to a baby after her immature eggs werematured in a lab and frozen for use five years after shewas left infertile by cancer treatment.
She gave birth to a healthy boynamed Jules whowas the first baby to be born through the new procedure, accordingto fertility specialists at Antoine Béclère University hospital in Clamart near Paris.
''Two more women, one who was treated for breast cancer and another who was treated for lymphoma, were now pregnant after having the same procedure at the hospital,'' said Michaël Grynberg, the head of reproductive medicine and fertility preservation at the hospital.
''While the procedure was not particularly efficient, it allowed some women to have babies when they had exhausted other options,'' he added.
The unnamed woman was offered fertility counselling when she was about to startherchemotherapy for breast cancer at the age of 29.
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The drugs used in many cancer treatments are known to put fertility at risk.Doctors had ruled out the standardIVFprocedure of using hormones to stimulate the woman’s ovaries to produce eggs as they wereconcerned it might adversely affect her cancer.
Another alternativeway was to remove and freeze some of the patient’s ovarian tissue and reimplant it when she recovered, but the woman considered the operation too invasive.
Instead, the woman opted for retrieval of early-stage eggs from her ovaries.These were matured in the lab and then vitrified, a process that freezes the cells rapidly in nitrogen to reduce the chances of ice crystals forming and rupturing them.
Watch: First ever 'test tube baby' describes impact of IVF for families
Out of her seven frozen eggs, six survived the process.These were fertilised with sperm injections, but only one developed into a healthy embryo that gave rise to the successful pregnancy.
The boy was born on 6 July 2019 when the woman was 34.Details of the birth were published in Annals of Oncology.
The medical team is working to make the procedure more efficient.Eggs have beenmatured in the lab beforeand used to create embryos that have gone on to produce live births but this was the first birth from an egg matured in the lab and then frozen before use.