Pfizer's Covid vaccine 73.2% effective in kids under 5, shows new data
Pfizer-BioNTech Covid vaccine
The Pfizer-BioNTech vaccine was authorised for children under 5 years of age in June, based on data that showed the vaccine generated a similar immune response as in older age groups. An early analysis based on 10 symptomatic COVID-19 cases in the study suggested a vaccine efficacy of 80.3%. But experts warned that the data was preliminary due to a low number of symptomatic cases.
The updated data showed 13 children had Covid, at least seven days after receiving a third dose of the Pfizer-BioNTech COVID-19 vaccine, compared with 21 cases among those who received a placebo.
New data from the companies showed that the vaccine was 73.2% effective in preventing COVID-19 among children aged 6 months through 4 years.
Most cases were caused by the Omicron BA.2 variant that was dominant in March and April, when the study was conducted.
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The companies on Monday applied for U.S. authorization of the bivalent vaccine as a booster for those aged 12 and above.
Pfizer said a paediatric trial for the Omicron-adapted vaccine would begin in the fall, and it would work with regulators to determine what data is needed for authorization.
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