The Islamabad-based think-tank in its report said Tehreek-e-Taliban and its associated groups remain a "potent threat", the report said, adding that nationalist-insurgent groups - Balochistan Liberation Army and Balochistan Liberation Front were also key organizations against Pakistan.
The report said there was an "alarming rise" in IS footprints in Balochistan and northern Sindh.
The think-tank noted that there were 370 terrorist attacks in 64 districts in Pakistan last year by militant, nationalist and insurgent groups. Although it declined 16 per cent from the previous year.
The report also said 131 per cent increase in cross-border attacks in Pakistan's border with India, Afghanistan and Iran with 171 incidents reported.
The think-tank said Pakistan security forces killed 524 militants during various encounters.
Balochistan and FATA, mainly Khurram Agency, remained critical areas with 288 and 253 terrorism-related killings in 2017.