Possible cure for HIV developed by UK researchers

WION London, United Kingdom Oct 05, 2016, 03.36 AM(IST)

ART is effective only on active HIV cells and not the ones which are 'resting or sleeping'. These cells store the HIV virus which allows the virus to return one ART stops attacking the active cells.? Photograph:( Getty )

 

The National Institute for Health Research (NIHR) in collaboration with five research universities in the UK, have found a possible cure for HIV infection after a patient showed no signs of the virus after the treatment, the NIHR website said. 

According to ANI, the man was the first to finish treatment and his blood tests did not detect the virus. However due to the Antiretroviral Therapy, the human immunodeficiency virus (HIV) disappears from the body. 

Mark Samuels, the managing director of the NOCRI "This is one of the first serious attempts at a full cure for HIV. We are exploring the real possibility of curing HIV. This is a huge challenge and it`s still early days but the progress has been remarkable," ANI quoted him saying.

The NIHR's Office for Clinical Research Infrastructure is leading the clinical trial called 'kick and kill' study with 50 HIV patients. The researchers activate the HIV cells which are asleep. They treat these activated cells with an HDAC drug to facilitate the body to fight the virus. 

Professor of HIV Medicine at Imperial College London, Sarah Fidler, who is leading the trial, told BBC "All the participants are taking antiretrovirals and so will have an undetectable viral load, which shows the great success of current treatment."

However, ART is effective only on active HIV cells and not the ones which are "resting or sleeping". These cells store the HIV virus which allows the virus to return one ART stops attacking the active cells. 

Currently, the Antiretroviral Therapy (ART) which is being used to treat the disease stops the virus from multiplying, which allows the immune system to recover. 

Mark Samuels said "HIV is able to hide from the immune system in dormant cells where highly sophisticated modern testing cannot find it, and therefore resist therapy," ANI reported.  

The participating universities include Oxford University, University of Cambridge, Imperial College London, King's College London and University College London.

(WION)