Donald Trump’s comments targeting Iran’s supreme leader came on Saturday shortly after Ayatollah Ali Khamenei’s X account posted a series of hostile messages, accusing the US president of being responsible for deadly violence and unrest in Iran.

‘It’s time to look for new leadership in Iran,’ says Trump, calls Khamenei a ‘sick man’

Iran has accused the United States of trying to engineer a pretext for military intervention by fuelling unrest and pushing for regime change. Here's what Tehran said.

Iran accuses US of plotting 'regime change' after Trump tells protesters, 'HELP IS ON ITS WAY'

Referring to the huge crowds hitting the streets in Iran as protests in the Islamic Republic entered the 12th day, President Donald Trump said the massive turnout at the demonstrations shows that the enthusiasm to overturn the current regime in Iran is incredible. 

‘Khamenei is looking to go someplace,’ says Trump as protests intensify in Iran

Amid this unrest, Supreme Leader Ayatollah Ali Khamenei delivered his first public address since the demonstrations began, calling for unity and denouncing foreign influence, while addressing the United States directly.

Iran 'rioters' want to please Trump; he should focus on US problems: 6 things Supreme Leader Khamenei said on protests

This comes after a member of the Iranian paramilitary force was killed during the demonstrations in the western part of the country as protests spread across more than two dozen cities.

‘Must be put in their place’: Khamenei warns rioters, says protesters’ demands ‘completely fair’

At the heart of the turmoil is Iran’s complex power structure, where unelected religious and military bodies wield decisive authority alongside elected institutions. Here is a guide to who really holds power in Tehran and how the system functions.

Iran protests: Who controls Tehran? Supreme Leader, President, IRGC and the Islamic Republic’s power web explained

Iran rejected the proposed “Trump Route” near its border, part of a US-brokered Armenia-Azerbaijan peace deal, warning it threatens regional security and vowing to block its implementation.

'Graveyard for Trump’s mercenaries': Iran vows to block US-brokered Azerbaijan-Armenia corridor near its border

Iran’s supreme leader, Ayatollah Ali Khamenei, on Wednesday (July 16) said that Israel waged the 12-day war against Tehran to incite regime change, adding that it was a strategy to ignite protests and bring people onto streets.

To incite regime change? Iran’s supreme leader Khamenei reveals why Israel waged 12-day war against Tehran

Dressed in traditional black mourning robes, the 86-year-old leader was seen on state television greeting a large crowd at the Imam Khomeini Mosque, where Shia Muslims were marking the martyrdom of Prophet Mohammed's grandson Imam Hussein.

Where was Khamenei hiding? Iran's Supreme Leader makes public appearance days after 12-day war with Israel

Tensions flare in Pune after Ayatollah Khameneis poster Irans flag surface

Tensions flare in Pune after Ayatollah Khamenei's poster, Iran's flag surface

Conflicts between these nations are not new. Iran has always remained one of the greatest adversaries of the US since the 1979 Islamic revolution, after Ayatollah Ruhollah Khomeini threw pro-Western Mohammad Reza Pahlavi out of power in Tehran.

EXPLAINED: Is Iran really a threat or a victim of US? Know history of 70 years of betrayals, coups and bombs

Iran on Saturday (Jun 28) slammed US President Donald Trump for his "disrespectful and unacceptable" comments about Iran's Supreme Leader, Ayatollah Ali Khamenei.

Was Khamenei left out of Iran-Israel ceasefire? Report claims Tehran agreed to Trump's offer without consulting Supreme Leader

Trump further warned that it will "only get worse!", hoping that the leadership of Iran would realize that "you often get more with HONEY than you do with VINEGAR."

'WILL ONLY GET WORSE': Trump's BIG WARNING to 'burned out' Iran after Khamenei claims victory over US regime

Calling him the "so-called Supreme Leader", Trump lambasted on Truth Social, saying that why would the Iranian leader so "blatantly and foolishly that he won the War with Israel" when he knows that it is a lie.

'SAVED HIM FROM VERY UGLY, IGNOMINIOUS DEATH': Trump says he knew where Khamenei was hidden, warns 'it'll only get worse'

After a 12-day intensive war and a shaky ceasefire with Israel, Iran has now denied continuing its long-due nuclear talks with America. Abbas Araghchi said there is that no agreement, arrangement or discussion has taken place regarding the initiation of new negotiations.

EXPLAINED: Why Ali Khamenei-led Iran backs off from its nuke talks with US

Inside Khameneis bunker Succession planning amid Israels assassination threats Report

Inside Khamenei’s bunker: Succession planning amid Israel's assassination threats-Report

Several old post of Supreme leader of Iran, Ayatollah Ali Khamenei has surfaced on social media showing liberal and feminist tone supporting for women’s rights.

'Women are stronger than men': Khamenei’s old posts go viral amid Israel-Iran tensions

Khamenei has been Iran’s top leader since 1989, after the death of the country’s first Supreme Leader, Ayatollah Ruhollah Khomeini. Khomeini led Iran for ten years after overthrowing Shah Mohammad Reza Pahlavi. 

Who is Ali Hosseini Khamenei, the supreme leader of Iran?

On 19 August 2013, the CIA officially acknowledged its role in the coup that removed Iran’s elected Prime Minister Mohammad Mossadegh. 

History repeating? This is how US engineered Iran’s 1953 coup and why it still matters

At the heart of Iran’s resistance is Khamenei himself, yet very few are aware that the man commanding Iran’s defiance traces his roots back to India.

Iran-Israel War: Ayatollah Ali Khamenei’s grandfather was linked to Uttar Pradesh? Here is what we know..

This was his first public statement since Israel carried out strikes on Iranian nuclear facilities and killed several senior Iranian commanders and scientists on 12 June.

Israel-Iran war: Khamenei's four-word reply to Trump's 'UNCONDITIONAL SURRENDER' warning - What did Iran's Supreme Leader say?

Khamenei's statement comes after US President Donald Trump on Tuesday (17 June) demanded a 'UNCONDITIONAL SURRENDER' and claimed that the United States knows the exact location of Khamenei but will not kill him, at least for now.

'US strike will have serious consequences': Khamenei says 'Iran will not surrender' in first address after Israel's strike - Here's what he said

Katz also confirmed that Israel had struck the headquarters of Iran’s state broadcaster IRIB in Tehran the day before. He warned that more sites linked to Iran’s civil regime may be targeted in upcoming operations.

'Remember his fate': Israel warns Khamenei will end up like Saddam Hussein - Who was he and what happened to him?

Israeli Prime Minister Benjamin Netanyahu has not kept it a secret that he would like Khamenei dead

Israel wants to kill Ali Khamenei but he's survived assassination bids in the past. Who wanted Iran Supreme Leader dead? A profile