In a groundbreaking breakthrough, American scientists have created functional human eggs using skin cells.
By replacing the DNA in an egg with genetic material from skin, researchers have taken a major step toward fertilisation without a biological mother.
This raises scientific possibilities — and ethical questions — about the future of human reproduction.

Babies could soon be born without biological mothers | Stem cells bring revolutionary change

Heart surgeon Massimo Caputo from the Briston Heart Institute used what is called stem cell scaffolding to correct a baby's heart defect. With this advanced technology, he hopes that children who are born with congenital cardiac disease won't need as many operations. Watch this to know more.

Doctors may have saved a baby's heart using umbilical stem cells

According to a new research, stem cells can be regrown in damaged umbilical cord.

Research by Notre Dame University revealed a "new strategy" that can restore the damaged stem cells and enable it to grow new tissues again.

<a href="https://www.wionews.com/world/stem-cell-transplant-cures-woman-of-hiv-researchers-report-453666">Also Read:&nbsp;Stem cell transplant cures HIV+&nbsp;woman, third person to be cured of infection</a>

The new approach is based on specially engineered "nanoparticles" which can store medicine and deliver it just to the stem cells by attaching directly to the stem cells’ surface. It is just 150 nanometres in diameter, the study said. The particles release the medicine slowly "making it highly effective even at very low doses".&nbsp;

Watch:&nbsp;Scientists create the world's first 'artificial' embryos

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Donny Hanjaya-Putra who conducted the study said: "it is smart and effective" while adding that, "Each stem cell is like a soldier. It knows where to go and what to do. But the ‘soldiers’ we are working with are injured and weak. By providing them with this nanoparticle ‘backpack,’ we are giving them what they need to work effectively again.”

The "backpacks" enabled the damaged stem cells to form new blood vessels during the experiment with mice. However, it could take many years before the new technique can become part of healthcare, scientists say.

The researchers said&nbsp;the new approach will help to restore cells damaged by pregnancy complications, so instead of discarding the stem cells, clinicians will be able to "rejuvenate" them and it will also help in "child’s developmental outcomes".

(With inputs from Agencies)

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According to a new research, stem cells can be regrown in damaged umbilical cord. Research by Notre Dame University revealed a "new strategy" that can restore the damaged stem cells and enable it to grow new tissues again.

According to a new research, stem cells can be regrown in damaged umbilical cord. Research by Notre Dame University revealed a "new strategy" that can restore the damaged stem cells and enable it to grow new tissues again. Also Read: Stem cell transplant cures HIV+ woman, third person to be cured of infection The new approach is based on specially engineered "nanoparticles" which can store medicine and deliver it just to the stem cells by attaching directly to the stem cells’ surface. It is just 150 nanometres in diameter, the study said. The particles release the medicine slowly "making it highly effective even at very low doses". Watch: Scientists create the world's first 'artificial' embryos Donny Hanjaya-Putra who conducted the study said: "it is smart and effective" while adding that, "Each stem cell is like a soldier. It knows where to go and what to do. But the ‘soldiers’ we are working with are injured and weak. By providing them with this nanoparticle ‘backpack,’ we are giving them what they need to work effectively again.” The "backpacks" enabled the damaged stem cells to form new blood vessels during the experiment with mice. However, it could take many years before the new technique can become part of healthcare, scientists say. The researchers said the new approach will help to restore cells damaged by pregnancy complications, so instead of discarding the stem cells, clinicians will be able to "rejuvenate" them and it will also help in "child’s developmental outcomes". (With inputs from Agencies) WATCH WION LIVE HERE

Saving the umbilical cord: Researchers show how damaged stem cells can be restored

Millions of people throughout the world suffer from baldness, and up until recently, hair implants were the only solution. But now, researchers might have discovered the cure for baldness. Researchers from the University of California found a single chemical in hair follicles that regulates both cell division and cell death. Given that follicles are a source of stem cells, this discovery could not only treat baldness but also aid in significantly reducing the time taken to recover from injuries.

A release by the university explains that the majority of cells in the human body have fixed forms and functions that are established during embryonic development. A blood cell, for instance, cannot transform into a neuron cell, and vice versa.&nbsp;

Also read |&nbsp;<a href="https://www.wionews.com/science/all-the-kissing-our-ancient-ancestors-did-is-what-gave-us-herpes-study-501356" hreflang="en">All the kissing our ancestors’ did is what gave us herpes: Study</a>

It goes on to say that stem cells, however, are similar to the empty Scrabble tiles in that they can develop into many kinds of cells. They can even be used to restore damaged tissue or organs due to their flexibility.

As study co-author and UC Riverside mathematical biologist, Qixuan Wang puts it,&nbsp;“In science fiction, when characters heal quickly from injuries, the idea is that stem cells allowed it.”&nbsp;

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Wang added: “In real life, our new research gets us closer to understanding stem cell behavior, so that we can control it and promote wound healing.”

While the stomach and liver can heal themselves after injuries, hair follicles are the only organ in humans that regenerate&nbsp;automatically and regularly, even without injury. This is why Wang’s team focused on them for their research.

Also read |&nbsp;<a href="https://www.wionews.com/world/the-earth-is-exhausted-mankind-has-already-used-up-its-resources-for-the-year-2022-501303" hreflang="en">Earth Overshoot Day: The planet is exhausted. Mankind has already used up its resources for the year 2022</a>

The scientists uncovered the mechanism by which a particular protein called TGF-beta regulates the process by which cells in hair follicles, including stem cells, divide and create new cells or plan their own demise, ultimately resulting in the death of the entire hair follicle.

Nobody is absolutely certain as to why follicles self-destruct. According to some theories, it is an inherited feature from animals that shed their fur to survive the hot summer months or to camouflage. If scientists can understand how TGF-beta activates cell division and interacts with other crucial genes, the scientific breakthroughs are endless.

(With inputs from agencies)

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Millions of people throughout the world suffer from baldness, and up until recently, hair implants were the only solution. But now, researchers might have discovered the cure for baldness.

Millions of people throughout the world suffer from baldness, and up until recently, hair implants were the only solution. But now, researchers might have discovered the cure for baldness. Researchers from the University of California found a single chemical in hair follicles that regulates both cell division and cell death. Given that follicles are a source of stem cells, this discovery could not only treat baldness but also aid in significantly reducing the time taken to recover from injuries. A release by the university explains that the majority of cells in the human body have fixed forms and functions that are established during embryonic development. A blood cell, for instance, cannot transform into a neuron cell, and vice versa. Also read | All the kissing our ancestors’ did is what gave us herpes: Study It goes on to say that stem cells, however, are similar to the empty Scrabble tiles in that they can develop into many kinds of cells. They can even be used to restore damaged tissue or organs due to their flexibility. As study co-author and UC Riverside mathematical biologist, Qixuan Wang puts it, “In science fiction, when characters heal quickly from injuries, the idea is that stem cells allowed it.” Watch | World Hepatitis Day: Expert tells WION how to save kids from disease Wang added: “In real life, our new research gets us closer to understanding stem cell behavior, so that we can control it and promote wound healing.” While the stomach and liver can heal themselves after injuries, hair follicles are the only organ in humans that regenerate automatically and regularly, even without injury. This is why Wang’s team focused on them for their research. Also read | Earth Overshoot Day: The planet is exhausted. Mankind has already used up its resources for the year 2022 The scientists uncovered the mechanism by which a particular protein called TGF-beta regulates the process by which cells in hair follicles, including stem cells, divide and create new cells or plan their own demise, ultimately resulting in the death of the entire hair follicle. Nobody is absolutely certain as to why follicles self-destruct. According to some theories, it is an inherited feature from animals that shed their fur to survive the hot summer months or to camouflage. If scientists can understand how TGF-beta activates cell division and interacts with other crucial genes, the scientific breakthroughs are endless. (With inputs from agencies) Watch WION LIVE HERE: You can now write for wionews.com and be a part of the community. Share your stories and opinions with us here.

Researchers examining hair may have found a way to cure baldness and regenerate damaged organs

In the first clinical trial of its kind, a Japanese university said Friday it successfully transplanted stem cells into a patient with spinal cord damage.

As of today, there are no effective treatments available for paralysis caused by serious spinal cord injuries, which affects more than 100,000 people in Japan alone.

Also read |&nbsp;<a href="https://www.wionews.com/science/researcher-says-insomnia-is-remnant-of-biphasic-sleep-not-a-disorder-443715" hreflang="en">Researcher says insomnia is remnant of biphasic sleep, not a disorder</a>

To treat the injuries, surgeons at Keio University in Tokyo are looking into induced pluripotent stem (iPS) cells.

iPS cells are created by stimulating mature, already specialised cells back into a juvenile state.

They can then be prompted to mature into different kinds of cells, with the Keio University study using iPS-derived cells of the neural stem.

Over two million iPS-derived cells were implanted into a patient's spinal cord last month as the first step in the trial.

Also read |&nbsp;<a href="https://www.wionews.com/world/western-diet-responsible-for-global-rise-of-autoimmune-diseases-say-researchers-443537" hreflang="en">Western diet responsible for global rise of autoimmune diseases, say researchers</a>

"This is definitely a huge step forward," Masaya Nakamura, a Keio University professor who heads the research, told reporters.

He noted that there is still "a lot of work to be done" before the treatment can be used.

In the first stage of the study, the researchers will confirm the safety of the transplant method.

An independent committee will monitor the patient for up to three months to determine whether the study can continue and other patients can receive transplants.

Watch |&nbsp;Gravitas: Pig's heart transplanted into a human

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In addition, the team hopes to determine if stem cell implants improve neurological function and quality of life.

The university received government approval for the trial in 2019, but recruitment was temporarily halted due to the COVID-19 pandemic.

The team is focusing on patients who were injured from 14 to 28 days before their operation; however, patient information remains confidential.

After safety experiments were conducted on animals, the researchers were able to determine the number of cells they would implant. They cautioned that although they would monitor for therapeutic effects, the primary objective was to study the safety of injecting the cells.

(With inputs from agencies)

In the first clinical trial of its kind, a Japanese university said Friday it successfully transplanted stem cells into a patient with spinal cord damage. As of today, there are no effective treatments available for paralysis caused by serious spinal cord injuries, which affects more than 100,000 people in Japan alone.

In the first clinical trial of its kind, a Japanese university said Friday it successfully transplanted stem cells into a patient with spinal cord damage. As of today, there are no effective treatments available for paralysis caused by serious spinal cord injuries, which affects more than 100,000 people in Japan alone. Also read | Researcher says insomnia is remnant of biphasic sleep, not a disorder To treat the injuries, surgeons at Keio University in Tokyo are looking into induced pluripotent stem (iPS) cells. iPS cells are created by stimulating mature, already specialised cells back into a juvenile state. They can then be prompted to mature into different kinds of cells, with the Keio University study using iPS-derived cells of the neural stem. Over two million iPS-derived cells were implanted into a patient's spinal cord last month as the first step in the trial. Also read | Western diet responsible for global rise of autoimmune diseases, say researchers "This is definitely a huge step forward," Masaya Nakamura, a Keio University professor who heads the research, told reporters. He noted that there is still "a lot of work to be done" before the treatment can be used. In the first stage of the study, the researchers will confirm the safety of the transplant method. An independent committee will monitor the patient for up to three months to determine whether the study can continue and other patients can receive transplants. Watch | Gravitas: Pig's heart transplanted into a human In addition, the team hopes to determine if stem cell implants improve neurological function and quality of life. The university received government approval for the trial in 2019, but recruitment was temporarily halted due to the COVID-19 pandemic. The team is focusing on patients who were injured from 14 to 28 days before their operation; however, patient information remains confidential. After safety experiments were conducted on animals, the researchers were able to determine the number of cells they would implant. They cautioned that although they would monitor for therapeutic effects, the primary objective was to study the safety of injecting the cells. (With inputs from agencies)

Japan carries out world-first spinal cord stem cell trial; a possible cure for spinal injury-related paralysis

Stem cell injected in macaque's embryo, in yet another experiment which pushes the boundaries of science and renews the debate around ethics. Scientists say the experiment will gain more info on early humans and diseases.

Stem cell injected in Macaque's embryo

Scientists in the US have developed the world's first living robots that can walk, swim using frogs' stem cells.&nbsp;

The living machines are named&nbsp;as Xenobots, after the African clawed frog (Xenopus laevis) from which they have taken their stem cells, reported CNN. The machines are less than a milimetre&nbsp;in size and look like a moving pink flesh.&nbsp;

Also read:&nbsp;<a href="https://www.wionews.com/world/smart-robots-in-the-offing-to-help-mine-the-moon-272277">Smart robots in the offing to help mine the moon</a>

Xenobots can swim, walk, survive for days without food and work together in groups.&nbsp;

Also read:&nbsp;<a href="https://www.wionews.com/world/robots-to-take-20-million-jobs-worsening-inequality-study-230459">Robots to take 20 million jobs, worsening inequality: Study</a>

The scientists scraped living stem cells from frog embryos. They left them to incubate. After this, the cells were cut and reshaped into specific "body forms", said a news release from the University of Vermont.

The cells later started to work on their own. The skin cells combined to form a structure and pulsing heart muscle cells enabled the robot to move on its own.&nbsp;

The robots also have self-healing capabilities.&nbsp;

Joshua Bongard, one of the main researchers of the project, described Xenobots as "novel machines". He also said the new robots are "artfact", "a living, programmable organism".&nbsp;

The study also claimed that robots are more environmental-friendly and safer for human health.&nbsp;

The robots can perform tasks such as cleaning radioactive waste, carrying medicine inside human bodies and collecting microplastics from the oceans, among others. They can be also placed in the arteries to scrape out plaque. &nbsp;&nbsp;

Scientists in the US have developed the world's first living robots that can walk, swim using frogs' stem cells. The living machines are named as Xenobots, after the African clawed frog (Xenopus laevis) from which they have taken their stem cells, reported CNN.

Scientists in the US have developed the world's first living robots that can walk, swim using frogs' stem cells. The living machines are named as Xenobots, after the African clawed frog (Xenopus laevis) from which they have taken their stem cells, reported CNN. The machines are less than a milimetre in size and look like a moving pink flesh. Also read: Smart robots in the offing to help mine the moon Xenobots can swim, walk, survive for days without food and work together in groups. Also read: Robots to take 20 million jobs, worsening inequality: Study The scientists scraped living stem cells from frog embryos. They left them to incubate. After this, the cells were cut and reshaped into specific "body forms", said a news release from the University of Vermont. The cells later started to work on their own. The skin cells combined to form a structure and pulsing heart muscle cells enabled the robot to move on its own. The robots also have self-healing capabilities. Joshua Bongard, one of the main researchers of the project, described Xenobots as "novel machines". He also said the new robots are "artfact", "a living, programmable organism". The study also claimed that robots are more environmental-friendly and safer for human health. The robots can perform tasks such as cleaning radioactive waste, carrying medicine inside human bodies and collecting microplastics from the oceans, among others. They can be also placed in the arteries to scrape out plaque.

Scientists develop world's first living robots using stem cells from frogs

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