The US and Iran were Cold War allies until the 1953 coup and the 1979 Islamic Revolution shattered ties. Hostage crises, sanctions, proxy wars, and the collapsed nuclear deal entrenched decades of hostility.

The US and Iran are standing against each other over Tehran's nuclear programme. A recent report claimed, citing defence officials, that America could launch a strike on Iran this Saturday (Feb 21). Meanwhile, US President Donald Trump said that talks are in progress with Tehran, but it has been proven over the years that it is "not easy to make a meaningful deal with Iran." Amid this, one must wonder if these two nations were always enemies? No, in fact, they were allies. SO what happened that changed everything?

In the 1950s, the United States supported Iran’s Shah, helping build nuclear capacity and signing the Treaty of Amity to strengthen ties. This made Tehran a key US partner against Soviet influence in the Middle East.

The CIA helped overthrow Iran’s elected PM Mossadegh, reinstating the Shah’s power. This fostered resentment among many Iranians, laying the groundwork for future distrust of the United States.

The Shah was overthrown in the Islamic Revolution, and Ayatollah Khomeini established a theocratic republic. Iran’s new regime labelled the United States the “Great Satan,” ending close relations and diplomatic cooperation.

In 1979, Iranian students seized the US Embassy and held diplomats hostage for 444 days, deeply damaging trust. Diplomatic relations were cut, and sanctions began shaping decades of hostility.

During the 1980s Iran–Iraq War, the US backed Iraq while Iran built influence via proxies. This entrenched indirect confrontation. The US later designated Iran a state sponsor of terrorism.

In 2015, the US and allies negotiated the Iran nuclear deal (JCPOA), limiting enrichment in exchange for sanctions relief. The U.S. withdrew in 2018, reimposed sanctions, and tensions rose again.