With the Big Three, Federer, Nadal and world number one Novak Djokovic showing little signs of giving up their stranglehold of men's tennis, here are the other quarter-finalists
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Rafael Nadal
Rafael Nadal beat Argentina's Juan Ignacio Londero 6-2, 6-3, 6-3 with another masterful display of claycourt tennis, although the match was more competitive than the scoreline suggests.
The Spaniard reached his 38th Grand Slam quarter-final where he will face Japan's Kei Nishikori.
Rafael Nadal stands three victories away from winning a jaw-dropping 12th French Open title after reaching the quarter-finals.
(Photograph:AFP)
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Novak Djokovic
Novak Djokovic claimed his fourth successive straight-sets victory on Monday, this time outclassing Germany's Jan-Lennard Struff.
The Serbian world number one and top seed's 6-3, 6-2, 6-2 victory means Djokovic is the first man to reach 10 successive quarter-finals at Roland Garros.
Things might be about to get tougher for Djokovic, though, with Germany's Alexander Zverev up next.
(Photograph:AFP)
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Roger Federer
Roger Federer's dream return to the French Open continued as the Swiss waltzed into quarter-finals by giving Argentine Leonardo Mayer a 6-2, 6-3, 6-3 masterclass.
The 20-times Grand Slam champion, back at Roland Garros after a three-year hiatus.
Things are likely to get trickier for Federer from now on as the third seed will next face a resurgent Stan Wawrinka, the champion in 2015.
(Photograph:AFP)
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Stan Wawrinka
Stan Wawrinka beat Stefanos Tsitsipas in his tracks in the match of the tournament on Sunday to set up a French Open quarter-final against fellow Swiss Roger Federer.
Giving away 14 years to the swashbuckling young Greek on a baking afternoon, 2015 champion Wawrinka prevailed in a riveting five-hour battle of the backhands in front of an enthralled Court Suzanne Lenglen crowd.
(Photograph:AFP)
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Dominic Thiem
Dominic Thiem, Last year's runner-up, made light work of Gael Monfils as he ended French presence in the singles draw with a no-nonsense 6-4, 6-4, 6-2 victory to reach the French Open quarter-finals.
The Austrian fourth seed, widely regarded as the man standing between a final showdown between world number one Novak Djokovic and 11-times champion Rafael Nadal, wiped 14th seed Monfils off Court Philippe Chatrier in expeditious fashion.
He will next face either Russian Karen Khachanov for a place in the last four.
(Photograph:AFP)
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Alexander Zverev
German fifth seed Alexander Zverev reached his second successive Roland Garros quarter-final on Monday with a 3-6, 6-2, 6-2, 7-6 (7/5) win over Italy's Fabio Fognini.
Zverev will face top seed and world number one Novak Djokovic for a place in the semi-finals.
Zverev is 2-2 against Djokovic in his career but won their only meeting on clay in the Italian Open final in 2017 in straight sets.
(Photograph:AFP)
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Kei Nishikori
Japan's Kei Nishikori edged out home favourite Benoit Paire in five sets, having resumed two sets to one ahead after the match was suspended by bad light the previous day.
Paire served for the match in the fifth set but Nishikori scrambled over the line to earn himself the dubious honour of a meeting with defending champion Rafael Nadal who has looked in commanding form so far as he bids for title number 12.
(Photograph:AFP)
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Karen Khachanov
Karen Khachanov reached his first Grand Slam quarter-final on Monday when he defeated Juan Martin del Potro 7-5, 6-3, 3-6, 6-3 at Roland Garros.
Tenth seed Khachanov is the first Russian to reach the last eight in Paris since Mikhail Youzhny in 2010.
The 23-year-old will face Austrian fourth seed Dominic Thiem, the runner-up to Rafael Nadal in the 2018 final, for a place in the semi-finals.