Two patients with advanced brain cancer have responded well in a small experimental trial of combining chemo and immunotherapy drugs.&nbsp;

In one situation, the life-threatening tumour appears to have gone, The Guardian reported.&nbsp;

Also read | <a href="http://wionews.com/science/study-reveals-whales-are-cancer-resistence-in-their-genes-366010">Study reveals whales are cancer resistence 'in their genes'</a>

However, researchers at the Institute of Cancer Research and the Royal Marsden hospital in London have stressed that these are early days but added that it was unusual that such a positive response has been generated in the early trial.&nbsp;

In the phase 1 trial named Ice-Cap, ten people were enrolled who had advance glioblastoma, a tumour similar to the one that killed US President Joe Biden's son Beau.&nbsp;

Two patients responded to the immunotherapy agent atezolizumab combined with ipatasertib.

Also read | <a href="http://wionews.com/world/exercising-can-help-reduce-chances-of-cancer-study-363708">Exercising can help reduce chances of cancer: Study</a>

Ipatasertib is a new precision drug that may have the potential to uncloak tumours to the immune system.&nbsp;

A majority of patients in the trial had tumours with defects in a gene called Pten and in four cases, including the two people who responded very well, the Pten gene did not work at all.&nbsp;

"Brain cancer is able to evade the immune system in complex ways and, until now, immunotherapy has not worked. However, by uncloaking the disease using a new drug called ipatasertib, this study suggests that we could make some brain cancers vulnerable to atezolizumab," Dr Juanita Lopez, who led the study said.&nbsp;

"We believe that our findings open the door to the further development of what could become a gamechanging treatment option for some patients with aggressive glioblastoma brain cancer. Patients with glioblastoma have very poor survival rates, and even fewer new treatment options coming through, so any advance in outcomes would be extremely welcome." 
&nbsp;

Two patients with advanced brain cancer have responded well in a small experimental trial of combining chemo and immunotherapy drugs. In one situation, the life-threatening tumour appears to have gone, The Guardian reported.

Two patients with advanced brain cancer have responded well in a small experimental trial of combining chemo and immunotherapy drugs. In one situation, the life-threatening tumour appears to have gone, The Guardian reported. Also read | Study reveals whales are cancer resistence 'in their genes' However, researchers at the Institute of Cancer Research and the Royal Marsden hospital in London have stressed that these are early days but added that it was unusual that such a positive response has been generated in the early trial. In the phase 1 trial named Ice-Cap, ten people were enrolled who had advance glioblastoma, a tumour similar to the one that killed US President Joe Biden's son Beau. Two patients responded to the immunotherapy agent atezolizumab combined with ipatasertib. Also read | Exercising can help reduce chances of cancer: Study Ipatasertib is a new precision drug that may have the potential to uncloak tumours to the immune system. A majority of patients in the trial had tumours with defects in a gene called Pten and in four cases, including the two people who responded very well, the Pten gene did not work at all. "Brain cancer is able to evade the immune system in complex ways and, until now, immunotherapy has not worked. However, by uncloaking the disease using a new drug called ipatasertib, this study suggests that we could make some brain cancers vulnerable to atezolizumab," Dr Juanita Lopez, who led the study said. "We believe that our findings open the door to the further development of what could become a gamechanging treatment option for some patients with aggressive glioblastoma brain cancer. Patients with glioblastoma have very poor survival rates, and even fewer new treatment options coming through, so any advance in outcomes would be extremely welcome."

Early findings suggest new drug could be 'gamechanging' to treat brain cancer

Russia on Thursday said that the US sanctions for alleged election interference and hacking will "not help" a possible summit between US President <a href="https://www.wionews.com/topics/joe-biden">Joe Biden </a>and his Russian counterpart Vladimir Putin.&nbsp;

The reaction came after the US media reported that Washington on Thursday will impose sanctions on over 30 Russian entities, expel more than 10 Russian diplomats&nbsp;from the US, and push an existing ban on US banks transacting in Russian government debt.

Watch |&nbsp;

<iframe allowfullscreen="" autoplay="1" frameborder="0" height="350" src="https://www.wionews.com/videos/nato-warned-russia-against-military-build-up-near-ukrainian-border-377642/embed" width="560"></iframe>

"What is currently being discussed -- likely sanctions -- will in no way help such a meeting. That is unambiguous," Kremlin spokesman Dmitry Peskov told journalists, as reported by news agency AFP.&nbsp;

On Tuesday, Biden invited Putin in a phone call for a summit on the neutral ground after tensions between the West and Russia intensified in recent weeks over the conflict in Ukraine.&nbsp;

Also read | <a href="https://www.wionews.com/world/us-to-slap-new-sanctions-on-russia-for-election-interference-cyber-attack-sources-377685">US to slap new sanctions on Russia for election interference, cyber attack: Sources</a>

The Kremlin spokesperson, however, said that it will up to both the president to decide whether the summit could go ahead or not.&nbsp;

A Russian troop formation on the Ukrainian border, where the government forces have been fighting pro-Russia separatists since 2014 has caused concerns in the West and issued warnings by NATO.&nbsp;

Though, in the Putin-Biden phone call, both leaders called for continual dialogue after ties between both the nations reached a new low when Biden described his Russian counterpart as a "killer" last month.

&nbsp; 
(With inputs from agencies)

Russia on Thursday said that the US sanctions for alleged election interference and hacking will "not help" a possible summit between US President Joe Biden and his Russian counterpart Vladimir Putin.

Russia on Thursday said that the US sanctions for alleged election interference and hacking will "not help" a possible summit between US President Joe Biden and his Russian counterpart Vladimir Putin. The reaction came after the US media reported that Washington on Thursday will impose sanctions on over 30 Russian entities, expel more than 10 Russian diplomats from the US, and push an existing ban on US banks transacting in Russian government debt. Watch | "What is currently being discussed -- likely sanctions -- will in no way help such a meeting. That is unambiguous," Kremlin spokesman Dmitry Peskov told journalists, as reported by news agency AFP. On Tuesday, Biden invited Putin in a phone call for a summit on the neutral ground after tensions between the West and Russia intensified in recent weeks over the conflict in Ukraine. Also read | US to slap new sanctions on Russia for election interference, cyber attack: Sources The Kremlin spokesperson, however, said that it will up to both the president to decide whether the summit could go ahead or not. A Russian troop formation on the Ukrainian border, where the government forces have been fighting pro-Russia separatists since 2014 has caused concerns in the West and issued warnings by NATO. Though, in the Putin-Biden phone call, both leaders called for continual dialogue after ties between both the nations reached a new low when Biden described his Russian counterpart as a "killer" last month. (With inputs from agencies)

US sanctions on Russia won't 'help' Biden-Putin summit: Kremlin

A new study has found that spanking may affect a child's brain development in ways similar to more extreme forms of violence.

The study led by Harvard researchers is based on existing work that shows heightened activity in some regions of the brains of children who face abuse in response to threat cues.&nbsp;

Also read | <a href="http://wionews.com/sports/child-abuse-lack-of-schooling-at-nbas-china-academies-report-317049">Child abuse, lack of schooling at NBA's China academies: report</a>

It found that the group that comprise children who had been spanked had a higher neural response in several areas of the prefrontal cortex (PFC), including in regions that are part of the salience network.&nbsp;

These regions of the brain react to cues in the environment that tend to be consequential, for instance, a threat, and may affect decision-making and processing of situations.

"We know that children whose families use corporal punishment are more likely to develop anxiety, depression, behaviour problems, and other mental health problems, but many people don't think about spanking as a form of violence," Katie A. McLaughlin, John L. Loeb Associate Professor of the Social Sciences, director of the Stress &amp; Development Lab in the Department of Psychology, and the senior researcher on the study said.

Also read | <a href="http://wionews.com/india-news/lok-sabha-takes-up-discussion-on-pocso-amendment-bill-239987">Bill to provide death penalty for child abuse in Lok Sabha</a>

"In this study, we wanted to examine whether there was an impact of spanking at a neurobiological level, in terms of how the brain is developing."

The researchers analysed data from a large study of children aged between 3 and 11.&nbsp;

They focused on 147 children aged around 10 and 11 who had been spanked, excluding those who had also faced more severe forms of violence.

Each participant lay in an MRI machine and watched a computer screen that displayed different photographs of actors making "fearful" and "neutral" faces.&nbsp;

A scanner was used to capture the child's brain activity in response to these faces and then analyses was done whether there has been a difference in responses on children who had been spanked and the ones who were not.&nbsp;

"On average, across the entire sample, fearful faces elicited greater activation than neutral faces in many regions throughout the brain … and children who were spanked demonstrated greater activation in multiple regions of PFC to fearful relative to neutral faces than children who were never spanked," the researchers wrote.

The study was published on Friday in the journal Child Development.&nbsp;

(With inputs from agencies) 
&nbsp;

A new study has found that spanking may affect a child's brain development in ways similar to more extreme forms of violence. The study led by Harvard researchers is based on existing work that shows heightened activity in some regions of the brains of children who face abuse in response to threat cues.

A new study has found that spanking may affect a child's brain development in ways similar to more extreme forms of violence. The study led by Harvard researchers is based on existing work that shows heightened activity in some regions of the brains of children who face abuse in response to threat cues. Also read | Child abuse, lack of schooling at NBA's China academies: report It found that the group that comprise children who had been spanked had a higher neural response in several areas of the prefrontal cortex (PFC), including in regions that are part of the salience network. These regions of the brain react to cues in the environment that tend to be consequential, for instance, a threat, and may affect decision-making and processing of situations. "We know that children whose families use corporal punishment are more likely to develop anxiety, depression, behaviour problems, and other mental health problems, but many people don't think about spanking as a form of violence," Katie A. McLaughlin, John L. Loeb Associate Professor of the Social Sciences, director of the Stress & Development Lab in the Department of Psychology, and the senior researcher on the study said. Also read | Bill to provide death penalty for child abuse in Lok Sabha "In this study, we wanted to examine whether there was an impact of spanking at a neurobiological level, in terms of how the brain is developing." The researchers analysed data from a large study of children aged between 3 and 11. They focused on 147 children aged around 10 and 11 who had been spanked, excluding those who had also faced more severe forms of violence. Each participant lay in an MRI machine and watched a computer screen that displayed different photographs of actors making "fearful" and "neutral" faces. A scanner was used to capture the child's brain activity in response to these faces and then analyses was done whether there has been a difference in responses on children who had been spanked and the ones who were not. "On average, across the entire sample, fearful faces elicited greater activation than neutral faces in many regions throughout the brain … and children who were spanked demonstrated greater activation in multiple regions of PFC to fearful relative to neutral faces than children who were never spanked," the researchers wrote. The study was published on Friday in the journal Child Development. (With inputs from agencies)

Spanking may affect children's brain development: Study

Canadian health authority on Tuesday reported the nation's first blood clotting case related to the Oxford-AstraZeneca jab.&nbsp;

Health Canada said a Quebec woman who had received the <a href="https://www.wionews.com/topics/coronavirus-vaccine">coronavirus vaccine </a>prepared by the Serum Institute of India was Canada's first case of blood clotting with low platelets.&nbsp;

Watch |&nbsp;

<div class="videoWrapper trancodeVideo"><iframe allowfullscreen="" autoplay="1" class="includeVideo" frameborder="0" height="350" src="https://www.wionews.com/videos/denmark-stops-use-of-astrazeneca-covid-19-vaccine-377651/embed" style="width:100%;max-width:560px;" width="560"></iframe></div>

<div class="videoWrapper trancodeVideo">&nbsp;</div>

<div class="videoWrapper trancodeVideo">"The person is at home now recovering," the authority said in a statement as reported by news agency AFP.&nbsp;</div>

However, Health Canada said that the country would continue to use the Oxford-AstraZeneca jab since its benefits against <a href="https://www.wionews.com/topics/coronavirus">Covid-19 </a>"outweigh the potential risks."&nbsp;

On Wednesday, Denmark became the first European nation to stop using the Oxford-AstraZeneca Covid-19 vaccine over safety fears, despite the World Health Organization (WHO) and European Medicines Agency (EMA) insisting that the drug is safe to use. &nbsp;

Also read | <a href="https://www.wionews.com/science/explainer-why-is-second-jab-of-coronavirus-vaccine-more-painful-377737">Explainer: Why is second jab of coronavirus vaccine more painful</a>

"Denmark's vaccination campaign will go ahead without the AstraZeneca vaccine," Danish Health Authority director Soren Brostrom told reporters.&nbsp;

Some European countries have reported a few blood clot cases after people received the Oxford-AstraZeneca vaccine, but WHO and EMA have insisted that these cases form a very small number among millions who have received the drug and no link between blood clots and the drug has been established.&nbsp;

(With inputs from agencies)

Canadian health authority on Tuesday reported the nation's first blood clotting case related to the Oxford-AstraZeneca jab. Health Canada said a Quebec woman who had received the coronavirus vaccine prepared by the Serum Institute of India was Canada's first case of blood clotting with low platelets.

Canadian health authority on Tuesday reported the nation's first blood clotting case related to the Oxford-AstraZeneca jab. Health Canada said a Quebec woman who had received the coronavirus vaccine prepared by the Serum Institute of India was Canada's first case of blood clotting with low platelets. Watch | "The person is at home now recovering," the authority said in a statement as reported by news agency AFP. However, Health Canada said that the country would continue to use the Oxford-AstraZeneca jab since its benefits against Covid-19 "outweigh the potential risks." On Wednesday, Denmark became the first European nation to stop using the Oxford-AstraZeneca Covid-19 vaccine over safety fears, despite the World Health Organization (WHO) and European Medicines Agency (EMA) insisting that the drug is safe to use. Also read | Explainer: Why is second jab of coronavirus vaccine more painful "Denmark's vaccination campaign will go ahead without the AstraZeneca vaccine," Danish Health Authority director Soren Brostrom told reporters. Some European countries have reported a few blood clot cases after people received the Oxford-AstraZeneca vaccine, but WHO and EMA have insisted that these cases form a very small number among millions who have received the drug and no link between blood clots and the drug has been established. (With inputs from agencies)

Canada reports first blood clot case linked to AstraZeneca vaccine

Instagram on Wednesday said it is testing a feature of hiding "like counts" in a bid to ease the pressure of getting approval from others.&nbsp;

"In 2019, we started hiding like counts for a small group of people to understand if it lessens some pressure when posting to Instagram," a Facebook spokesperson told news agency AFP.

Also read | <a href="https://www.wionews.com/technology/facebook-testing-video-speed-dating-app-sparked-377364">Facebook testing video speed dating app 'Sparked'&nbsp;</a>

"Some people found this beneficial but some still wanted to see like counts so they could track what’s popular."

It has been often seen that social media users keep a check on the number of people who have "liked" their content and builds pressure of increasing one's social acceptance and popularity, especially amongst the youth.

Also read | <a href="https://www.wionews.com/technology/instagram-launches-new-stickers-on-ramzan-heres-how-to-use-them-377488">Instagram launches new stickers on Ramzan, here's how to use them</a>

This has also led to addictive and adverse effects on one's mental health.&nbsp;

With this experiment, Instagram is allowing a small number of people across the world the option whether they want other people to see the number of "likes" on their posts.

"We're testing this on Instagram to start, but we're also exploring a similar experience for Facebook," the spokesperson added.&nbsp;

Facebook said it was working with experts to see that the design tweaks such as this one on Instagram can help users well-being.&nbsp;

 
&nbsp;

Instagram on Wednesday said it is testing a feature of hiding "like counts" in a bid to ease the pressure of getting approval from others. "In 2019, we started hiding like counts for a small group of people to understand if it lessens some pressure when posting to Instagram," a Facebook spokesperson told news agency AFP.

Instagram on Wednesday said it is testing a feature of hiding "like counts" in a bid to ease the pressure of getting approval from others. "In 2019, we started hiding like counts for a small group of people to understand if it lessens some pressure when posting to Instagram," a Facebook spokesperson told news agency AFP. Also read | Facebook testing video speed dating app 'Sparked' "Some people found this beneficial but some still wanted to see like counts so they could track what’s popular." It has been often seen that social media users keep a check on the number of people who have "liked" their content and builds pressure of increasing one's social acceptance and popularity, especially amongst the youth. Also read | Instagram launches new stickers on Ramzan, here's how to use them This has also led to addictive and adverse effects on one's mental health. With this experiment, Instagram is allowing a small number of people across the world the option whether they want other people to see the number of "likes" on their posts. "We're testing this on Instagram to start, but we're also exploring a similar experience for Facebook," the spokesperson added. Facebook said it was working with experts to see that the design tweaks such as this one on Instagram can help users well-being.

Instagram launches experiment to hide 'likes'

In China it was fengcheng. In Spain it was el confinamiento. In France it was le confinement. In Britain it was known as lockdown, plain and simple — but it had the distinction of being one of the longest and most stringent in the world.

On Monday, that finally began drawing to an end.

Watch |&nbsp;

<div class="videoWrapper trancodeVideo"><iframe allowfullscreen="" autoplay="1" class="includeVideo" frameborder="0" height="350" src="https://www.wionews.com/videos/uk-covid-variant-doesnt-lead-to-severe-illness-death-the-lancet-377400/embed" style="width:100%;max-width:560px;" width="560"></iframe></div>

After months of coronavirus restrictions that encroached on almost every aspect of daily life, the English celebrated a hopeful new chapter, many of them in what seemed the most fitting way possible: with a pint at a pub.

“It’s like being out of prison,” said Kate Asani, who was sitting at a small table with two friends in the back garden of the Carlton Tavern in the Kilburn area of London, where they basked in one another’s company as much as in the sunshine.

For people across Europe, struggling with yet another wave of the pandemic and demoralized by a vaccine rollout that, outside Britain, has been deeply troubled, this is hardly a time to rejoice.

And Britons — who have lost more than 150,000 people to the pandemic — know better than anyone that they are facing a wily adversary, a shape-shifter of a virus that spins off variants that can threaten medical advances with a few mutations.

But just past the stroke of midnight Monday, a few select establishments in England served their first drinks since being forced to close in December and January, and more than a year after the first of three national lockdowns was imposed to limit the spread of the virus.

Later in the morning, thousands of gyms, salons and retail stores opened their doors for the first time in months, bringing a frisson of life to streets long frozen in a state of suspended animation. Friends reunited, and families shared a meal at outdoor cafes for the first time in months.

The weather may have been chilly — there were even some snow flurries — and pubs were limited to outdoor service. But the moment was embraced with an enthusiasm born of more than a year of on-and-off deprivation and uncertainty, one in which a once-unimaginable level of government decree became a way of life.

Prime Minister Boris Johnson called it “a major step forward in our road map to freedom.”

Monday marked the start of a phased reopening that is scheduled to culminate on June 21, when the government says it hopes to lift almost all restrictions in England. Scotland, Wales and Northern Ireland are following separate but similar timetables, which means that some of the restrictions eased on Monday in England will remain in place a while longer in those places.

Lockdowns of one form or another have become so commonplace around the world that it can be hard to recall a time when they did not exist. The word began entering the popular lexicon in the weeks and months after the virus first emerged in China and authorities there moved aggressively to restrict the movement of its citizens.

Images from the ghostly streets of Wuhan riveted the world’s attention, and it soon became clear that the virus respected no national borders. But there was debate over whether Western democracies could — or should — resort to the extreme measures taken by Beijing.

As hospitals struggled to deal with a flood of patients and death tolls soared, the debate was overtaken by the undeniable reality that traditional methods of infectious disease control, like testing and contact tracing, had failed.

And so lockdowns became a way of life.

While no country matched China’s draconian measures, liberal democracies have been engaged in a yearlong effort to balance economic, political and public health concerns. Last spring, that meant about 4 billion people — half of humanity — living under some form of stay-at-home order.

Britain, which held out longer than many of its European neighbors, entered its first national lockdown on March 26, 2020.

Although it is difficult to compare lockdowns, researchers at the Blavatnik School of Government at the University of Oxford have developed a system ranking their stringency. They found that Britain had spent 175 days at its “maximum stringency level.”

“In this sense, we can say that the U.K. is globally unique in spending the longest period of time at a very high level of stringency,” said Thomas Hale, an associate professor of global public policy at Oxford.

At the height of the epidemic in January, Britain was averaging almost 60,000 new coronavirus infections and more than 1,200 COVID-19 deaths each day. In the past week, the daily averages were about 2,500 cases and 36 fatalities.

On Monday, as Britons flocked to stores and restaurants, there was widespread hope that after so many false dawns, there will be no going back. The return of the pub only enhanced that optimism.

It is hard to find a year quite like the last one for one of Britain’s most cherished institutions. Through plagues and fires, wars and depressions, the nation’s pubs largely stayed open, and when they were first shut down last year, even the prime minister sounded shaken.

“I do accept that what we’re doing is extraordinary,” Johnson said in March last year. “We’re taking away the ancient, inalienable right of freeborn people of the United Kingdom to go to the pub.”

Days earlier, Johnson’s recommendation that the public voluntarily stay away from pubs and other social venues was not universally well received. His own father said: “Of course I’ll go to a pub if I need to go to a pub.”

It was not just pubs that suffered under lockdown. Retail stores, too, struggled to survive.

The flagship store of British retailer Topshop on Oxford Circus, once a destination for fashion-hungry young adults, permanently shut its doors after its parent company filed for bankruptcy last year. And plywood boards now cover the front of Debenhams, another retail chain that foundered during the pandemic.

The two companies crumbled within days of one another, as the country bounced from one lockdown to the next and the pandemic hastened the end of British high-street brands that were already teetering on the edge.

But now, those stores that have survived are hoping for a heyday, after the worst recession in decades.

Retailers hope that there will be a splurge in spending by people who have amassed a record amount of savings, nearly $250 billion according to government estimates, roughly 10% of Britain’s gross domestic product.

Plastered in big letters on the shop front of John Lewis, a British department store, there was an invitation coupled with a fingers-crossed prediction: “Come on in London, brighter days are coming.” 
&nbsp;

In China it was fengcheng. In Spain it was el confinamiento. In France it was le confinement. In Britain it was known as lockdown, plain and simple — but it had the distinction of being one of the longest and most stringent in the world.

In China it was fengcheng. In Spain it was el confinamiento. In France it was le confinement. In Britain it was known as lockdown, plain and simple — but it had the distinction of being one of the longest and most stringent in the world. On Monday, that finally began drawing to an end. Watch | After months of coronavirus restrictions that encroached on almost every aspect of daily life, the English celebrated a hopeful new chapter, many of them in what seemed the most fitting way possible: with a pint at a pub. “It’s like being out of prison,” said Kate Asani, who was sitting at a small table with two friends in the back garden of the Carlton Tavern in the Kilburn area of London, where they basked in one another’s company as much as in the sunshine. For people across Europe, struggling with yet another wave of the pandemic and demoralized by a vaccine rollout that, outside Britain, has been deeply troubled, this is hardly a time to rejoice. And Britons — who have lost more than 150,000 people to the pandemic — know better than anyone that they are facing a wily adversary, a shape-shifter of a virus that spins off variants that can threaten medical advances with a few mutations. But just past the stroke of midnight Monday, a few select establishments in England served their first drinks since being forced to close in December and January, and more than a year after the first of three national lockdowns was imposed to limit the spread of the virus. Later in the morning, thousands of gyms, salons and retail stores opened their doors for the first time in months, bringing a frisson of life to streets long frozen in a state of suspended animation. Friends reunited, and families shared a meal at outdoor cafes for the first time in months. The weather may have been chilly — there were even some snow flurries — and pubs were limited to outdoor service. But the moment was embraced with an enthusiasm born of more than a year of on-and-off deprivation and uncertainty, one in which a once-unimaginable level of government decree became a way of life. Prime Minister Boris Johnson called it “a major step forward in our road map to freedom.” Monday marked the start of a phased reopening that is scheduled to culminate on June 21, when the government says it hopes to lift almost all restrictions in England. Scotland, Wales and Northern Ireland are following separate but similar timetables, which means that some of the restrictions eased on Monday in England will remain in place a while longer in those places. Lockdowns of one form or another have become so commonplace around the world that it can be hard to recall a time when they did not exist. The word began entering the popular lexicon in the weeks and months after the virus first emerged in China and authorities there moved aggressively to restrict the movement of its citizens. Images from the ghostly streets of Wuhan riveted the world’s attention, and it soon became clear that the virus respected no national borders. But there was debate over whether Western democracies could — or should — resort to the extreme measures taken by Beijing. As hospitals struggled to deal with a flood of patients and death tolls soared, the debate was overtaken by the undeniable reality that traditional methods of infectious disease control, like testing and contact tracing, had failed. And so lockdowns became a way of life. While no country matched China’s draconian measures, liberal democracies have been engaged in a yearlong effort to balance economic, political and public health concerns. Last spring, that meant about 4 billion people — half of humanity — living under some form of stay-at-home order. Britain, which held out longer than many of its European neighbors, entered its first national lockdown on March 26, 2020. Although it is difficult to compare lockdowns, researchers at the Blavatnik School of Government at the University of Oxford have developed a system ranking their stringency. They found that Britain had spent 175 days at its “maximum stringency level.” “In this sense, we can say that the U.K. is globally unique in spending the longest period of time at a very high level of stringency,” said Thomas Hale, an associate professor of global public policy at Oxford. At the height of the epidemic in January, Britain was averaging almost 60,000 new coronavirus infections and more than 1,200 COVID-19 deaths each day. In the past week, the daily averages were about 2,500 cases and 36 fatalities. On Monday, as Britons flocked to stores and restaurants, there was widespread hope that after so many false dawns, there will be no going back. The return of the pub only enhanced that optimism. It is hard to find a year quite like the last one for one of Britain’s most cherished institutions. Through plagues and fires, wars and depressions, the nation’s pubs largely stayed open, and when they were first shut down last year, even the prime minister sounded shaken. “I do accept that what we’re doing is extraordinary,” Johnson said in March last year. “We’re taking away the ancient, inalienable right of freeborn people of the United Kingdom to go to the pub.” Days earlier, Johnson’s recommendation that the public voluntarily stay away from pubs and other social venues was not universally well received. His own father said: “Of course I’ll go to a pub if I need to go to a pub.” It was not just pubs that suffered under lockdown. Retail stores, too, struggled to survive. The flagship store of British retailer Topshop on Oxford Circus, once a destination for fashion-hungry young adults, permanently shut its doors after its parent company filed for bankruptcy last year. And plywood boards now cover the front of Debenhams, another retail chain that foundered during the pandemic. The two companies crumbled within days of one another, as the country bounced from one lockdown to the next and the pandemic hastened the end of British high-street brands that were already teetering on the edge. But now, those stores that have survived are hoping for a heyday, after the worst recession in decades. Retailers hope that there will be a splurge in spending by people who have amassed a record amount of savings, nearly $250 billion according to government estimates, roughly 10% of Britain’s gross domestic product. Plastered in big letters on the shop front of John Lewis, a British department store, there was an invitation coupled with a fingers-crossed prediction: “Come on in London, brighter days are coming.”

Britain rejoices and asks: Are lockdowns finally finished?

President Joe Biden announced Wednesday it's "time to end" America's longest war with the unconditional withdrawal of troops from Afghanistan where they have spent two decades in a bloody, largely fruitless battle against the Taliban.

Dubbed the "forever war," the US military onslaught in Afghanistan began in response to the September 11, 2001 terrorist attacks against the United States.

Watch |&nbsp;

<div class="videoWrapper trancodeVideo"><iframe allowfullscreen="" autoplay="1" class="includeVideo" frameborder="0" height="350" src="https://www.wionews.com/videos/biden-to-pull-out-all-us-troops-from-afghanistan-by-september-11-377553/embed" style="width:100%;max-width:560px;" width="560"></iframe></div>

&nbsp;

Now, 20 years later -- after almost 2,400 US military and tens of thousands of Afghan deaths -- Biden is naming September 11 as the deadline by which the last US soldiers will have finally departed.

The war is at best at a stalemate.

The internationally backed government in Kabul has only tenuous control in swaths of the country, while the Taliban are growing in strength, with many predicting the insurgency will seek to regain total power once the government's US military umbrella is removed.

In a speech later Wednesday, Biden was to tell Americans that it's time to accept the reality that there's no alternative to a clean break.

"We cannot continue the cycle of extending or expanding our military presence in Afghanistan hoping to create the ideal conditions for our withdrawal, expecting a different result," he was to say, according to excerpts released ahead of his speech.

"I am now the fourth American president to preside over an American troop presence in Afghanistan. Two Republicans. Two Democrats," he said. "I will not pass this responsibility to a fifth."

Biden's decision is not a shock. The war is hugely unpopular among voters and Biden's predecessor Donald Trump had committed to an even earlier exit of May 1.

Biden ally Senator Bernie Sanders called it "brave."

However, there was immediate criticism from some quarters that the United States is abandoning the Afghan government and encouraging jihadist insurgencies.

"Wars don't end when one side abandons the fight," influential Republican Representative Liz Cheney said.

"Withdrawing our forces from Afghanistan by Sept 11 will only embolden the very jihadists who attacked our homeland on that day 20 years ago."

'Recipe' for forever war&nbsp;

Biden was set to say in his speech that Washington will continue to support the Afghan government, only not "militarily."

This will mark a profound shift in clout for the beleaguered government and its US and coalition-trained security forces.

A senior administration official said the US military exit would be completed by September 11.

Biden had earlier considered stationing a residual US force to strike at Al-Qaeda or other international jihadist groups in Afghanistan or making withdrawal contingent on progress on the ground or in slow-moving peace talks.

In the end, he decided to leave only personnel to guard installations like the US embassy in Kabul, a senior official said.

"The president has judged that a conditions-based approach, which has been the approach of the past two decades, is a recipe for staying in Afghanistan forever," the official told reporters on condition of anonymity.

US Secretary of State Antony Blinken said the moment had arrived to bring forces back home, and Washington would work out a "coordinated" withdrawal plan with its NATO allies.

"Together, we have achieved the goals that we set out to achieve and now it is time to bring our forces home," Blinken said ahead of talks with NATO partners in Brussels.&nbsp;

German Defence Minister Annegret Kramp-Karrenbauer said Wednesday that NATO would likely join the US in withdrawing its troops by September.&nbsp;

The Times newspaper said Britain would withdraw its roughly 750 troops, citing sources as saying "they would struggle without American support because of a reliance on US bases and infrastructure."

Taliban 'confident'&nbsp;

The Biden official said the withdrawal would begin in May and that the delay was largely logistical, with troops possibly out of Afghanistan well before September 11.

The official warned the Taliban -- who are observing a truce with US but not with Afghan forces -- not to strike coalition forces as they leave, saying that in response to any attack "we will hit back hard."

But a threat assessment report published Tuesday by the director of US national intelligence said the Taliban "is confident it can achieve military victory."&nbsp;

The upheaval raises big questions over the future of attempts to modernize Afghanistan, especially for Afghan women who have benefited from increased rights, like access to education.

The Taliban, who enforce an austere brand of Sunni Islam, banned women from schools, offices, music and most of daily life during their 1996-2001 rule over much of Afghanistan. Two decades later, 40 percent of schoolchildren are girls.

Peace effort in Turkey&nbsp;

Biden's decision came as Turkey said it will host a US-backed peace conference from April 24 to May 4 that would bring together the Afghan government, the Taliban and international partners.

But Mohammad Naeem, spokesman for the Taliban office in Qatar, said the insurgents will not participate in any conference on Afghanistan's future "until all foreign forces completely withdraw."

A decade ago, the United States had about 100,000 troops in Afghanistan.

The troop figure by the end of Trump's presidency had gone down to 2,500. As of February this year, NATO had around 10,000 troops in Afghanistan. 
&nbsp;

President Joe Biden announced Wednesday it's "time to end" America's longest war with the unconditional withdrawal of troops from Afghanistan where they have spent two decades in a bloody, largely fruitless battle against the Taliban.

President Joe Biden announced Wednesday it's "time to end" America's longest war with the unconditional withdrawal of troops from Afghanistan where they have spent two decades in a bloody, largely fruitless battle against the Taliban. Dubbed the "forever war," the US military onslaught in Afghanistan began in response to the September 11, 2001 terrorist attacks against the United States. Watch | Now, 20 years later -- after almost 2,400 US military and tens of thousands of Afghan deaths -- Biden is naming September 11 as the deadline by which the last US soldiers will have finally departed. The war is at best at a stalemate. The internationally backed government in Kabul has only tenuous control in swaths of the country, while the Taliban are growing in strength, with many predicting the insurgency will seek to regain total power once the government's US military umbrella is removed. In a speech later Wednesday, Biden was to tell Americans that it's time to accept the reality that there's no alternative to a clean break. "We cannot continue the cycle of extending or expanding our military presence in Afghanistan hoping to create the ideal conditions for our withdrawal, expecting a different result," he was to say, according to excerpts released ahead of his speech. "I am now the fourth American president to preside over an American troop presence in Afghanistan. Two Republicans. Two Democrats," he said. "I will not pass this responsibility to a fifth." Biden's decision is not a shock. The war is hugely unpopular among voters and Biden's predecessor Donald Trump had committed to an even earlier exit of May 1. Biden ally Senator Bernie Sanders called it "brave." However, there was immediate criticism from some quarters that the United States is abandoning the Afghan government and encouraging jihadist insurgencies. "Wars don't end when one side abandons the fight," influential Republican Representative Liz Cheney said. "Withdrawing our forces from Afghanistan by Sept 11 will only embolden the very jihadists who attacked our homeland on that day 20 years ago." 'Recipe' for forever war Biden was set to say in his speech that Washington will continue to support the Afghan government, only not "militarily." This will mark a profound shift in clout for the beleaguered government and its US and coalition-trained security forces. A senior administration official said the US military exit would be completed by September 11. Biden had earlier considered stationing a residual US force to strike at Al-Qaeda or other international jihadist groups in Afghanistan or making withdrawal contingent on progress on the ground or in slow-moving peace talks. In the end, he decided to leave only personnel to guard installations like the US embassy in Kabul, a senior official said. "The president has judged that a conditions-based approach, which has been the approach of the past two decades, is a recipe for staying in Afghanistan forever," the official told reporters on condition of anonymity. US Secretary of State Antony Blinken said the moment had arrived to bring forces back home, and Washington would work out a "coordinated" withdrawal plan with its NATO allies. "Together, we have achieved the goals that we set out to achieve and now it is time to bring our forces home," Blinken said ahead of talks with NATO partners in Brussels. German Defence Minister Annegret Kramp-Karrenbauer said Wednesday that NATO would likely join the US in withdrawing its troops by September. The Times newspaper said Britain would withdraw its roughly 750 troops, citing sources as saying "they would struggle without American support because of a reliance on US bases and infrastructure." Taliban 'confident' The Biden official said the withdrawal would begin in May and that the delay was largely logistical, with troops possibly out of Afghanistan well before September 11. The official warned the Taliban -- who are observing a truce with US but not with Afghan forces -- not to strike coalition forces as they leave, saying that in response to any attack "we will hit back hard." But a threat assessment report published Tuesday by the director of US national intelligence said the Taliban "is confident it can achieve military victory." The upheaval raises big questions over the future of attempts to modernize Afghanistan, especially for Afghan women who have benefited from increased rights, like access to education. The Taliban, who enforce an austere brand of Sunni Islam, banned women from schools, offices, music and most of daily life during their 1996-2001 rule over much of Afghanistan. Two decades later, 40 percent of schoolchildren are girls. Peace effort in Turkey Biden's decision came as Turkey said it will host a US-backed peace conference from April 24 to May 4 that would bring together the Afghan government, the Taliban and international partners. But Mohammad Naeem, spokesman for the Taliban office in Qatar, said the insurgents will not participate in any conference on Afghanistan's future "until all foreign forces completely withdraw." A decade ago, the United States had about 100,000 troops in Afghanistan. The troop figure by the end of Trump's presidency had gone down to 2,500. As of February this year, NATO had around 10,000 troops in Afghanistan.

Biden says 'time to end' US war in Afghanistan with total pullout

How Indian cities, states fighting coronavirus as concerns mount

Did you know that a few species exist that can change the size of their brain?

There are a handful of species too that can change it back to their original size, according to a new research.

The name of these insect species is Indian jumping ants.&nbsp;

This species colony do not perish once their queen loses her life, and instead, "chosen" workers take her position, with expanded ovaries and shrunken brains to create offspring, reports The Guardian.&nbsp;

However, if a worker's "pseudo-queen" status is taken back, their bodies can bounce back, according to the study.&nbsp;

Generally, it is decided at the larval stage whether an ant will be a worker or a queen.&nbsp;

If an ant is well-fed and has the right hormones, it has the potential to become a big queen. &nbsp;

Otherwise, it has to remain as a sterile worker unless the species is an Indian jumping ant.&nbsp;

"They have this ability to completely transform themselves at the adult stage, and that makes them interesting to try to understand," lead author Dr Clint Penick from US-based Kennesaw State University said.&nbsp;

Insects such as ants follow a caste-based model in which the queen acts as the sole reproducer by secreting pheromones and do not let other female worker ants lay eggs.

The worker ants are to job like hunting for food, cleaning, caring for the young ones, among others.&nbsp;

But, unlike typical colonies that cease to exist following the death of the queen, Indian jumping ant colonies are functionally immortal. 
&nbsp;

Did you know that a few species exist that can change the size of their brain? There are a handful of species too that can change it back to their original size, according to a new research.

Did you know that a few species exist that can change the size of their brain? There are a handful of species too that can change it back to their original size, according to a new research. The name of these insect species is Indian jumping ants. This species colony do not perish once their queen loses her life, and instead, "chosen" workers take her position, with expanded ovaries and shrunken brains to create offspring, reports The Guardian. However, if a worker's "pseudo-queen" status is taken back, their bodies can bounce back, according to the study. Generally, it is decided at the larval stage whether an ant will be a worker or a queen. If an ant is well-fed and has the right hormones, it has the potential to become a big queen. Otherwise, it has to remain as a sterile worker unless the species is an Indian jumping ant. "They have this ability to completely transform themselves at the adult stage, and that makes them interesting to try to understand," lead author Dr Clint Penick from US-based Kennesaw State University said. Insects such as ants follow a caste-based model in which the queen acts as the sole reproducer by secreting pheromones and do not let other female worker ants lay eggs. The worker ants are to job like hunting for food, cleaning, caring for the young ones, among others. But, unlike typical colonies that cease to exist following the death of the queen, Indian jumping ant colonies are functionally immortal.

Meet Indian jumping ants, who can shrink and re-grow their brains

Denmark on Tuesday banned the use of Oxford-AstraZeneca <a href="https://www.wionews.com/topics/coronavirus-vaccine">coronavirus vaccine</a>, becoming the first European nation to take such action over rare but serious suspected health risks.&nbsp;

"Denmark's vaccination campaign will go ahead without the AstraZeneca vaccine," Danish Health Authority director Soren Brostrom in a press conference was quoted as saying by news agency AFP.&nbsp;

Watch |&nbsp;

<div class="videoWrapper trancodeVideo"><iframe allowfullscreen="" autoplay="1" class="includeVideo" frameborder="0" height="350" src="https://www.wionews.com/videos/study-finds-inactive-people-more-likely-to-die-of-covid-19-377530/embed" style="width:100%;max-width:560px;" width="560"></iframe></div>

The decision comes as Germany announced that people aged under 60 who had received the first dose of AstraZeneca jab will receive a different Covid-19 vaccine for their second dose.&nbsp;

Among millions of doses of AstraZeneca vaccine that have been administered, there have been a few blood clot cases and the World Health Organization and the European Medicines Agency (EMA) have shrugged off fears related to the vaccine.&nbsp;

The clots appear in veins in the brain, known as cerebral venous sinus thrombosis, CVST, as well as in the abdomen and arteries.&nbsp;

Also read | <a href="https://www.wionews.com/science/covid-19-virus-can-sustain-itself-for-up-to-a-month-in-dust-study-377452">COVID-19 virus can sustain itself for up to a month in dust: Study</a>

According to the EMA, 222 cases of atypical thromboses have been detected out of 34 million AstraZeneca doses in European Economic Area (EU, Iceland, Norway, Liechtenstein) and Britain, as of April 4.

There have been 18 deaths too according to this condition as of March 22.&nbsp;

Meanwhile, South Africa has suspended the use of Johnson &amp; Johnson vaccine over potential blood clot risks reported by the US, the health minister said.

(With inputs from agencies)

Denmark on Tuesday banned the use of Oxford-AstraZeneca coronavirus vaccine, becoming the first European nation to take such action over rare but serious suspected health risks.

Denmark on Tuesday banned the use of Oxford-AstraZeneca coronavirus vaccine, becoming the first European nation to take such action over rare but serious suspected health risks. "Denmark's vaccination campaign will go ahead without the AstraZeneca vaccine," Danish Health Authority director Soren Brostrom in a press conference was quoted as saying by news agency AFP. Watch | The decision comes as Germany announced that people aged under 60 who had received the first dose of AstraZeneca jab will receive a different Covid-19 vaccine for their second dose. Among millions of doses of AstraZeneca vaccine that have been administered, there have been a few blood clot cases and the World Health Organization and the European Medicines Agency (EMA) have shrugged off fears related to the vaccine. The clots appear in veins in the brain, known as cerebral venous sinus thrombosis, CVST, as well as in the abdomen and arteries. Also read | COVID-19 virus can sustain itself for up to a month in dust: Study According to the EMA, 222 cases of atypical thromboses have been detected out of 34 million AstraZeneca doses in European Economic Area (EU, Iceland, Norway, Liechtenstein) and Britain, as of April 4. There have been 18 deaths too according to this condition as of March 22. Meanwhile, South Africa has suspended the use of Johnson & Johnson vaccine over potential blood clot risks reported by the US, the health minister said. (With inputs from agencies)

Denmark becomes first European nation to stop using AstraZeneca vaccine

US Secretary of State Antony Blinken on Wednesday said that the moment has arrived to bring the foreign troops home, adding that Washington would engage with NATO allies on a "coordinated" pull-out.&nbsp;

"Together, we have achieved the goals that we set out to achieve and now it is time to bring our forces home," Blinken was quoted as saying by news agency AFP ahead of talks with NATO nations in Brussels.&nbsp;

Watch |&nbsp;

<div class="videoWrapper trancodeVideo"><iframe allowfullscreen="" autoplay="1" class="includeVideo" frameborder="0" height="350" src="https://www.wionews.com/videos/antony-blinken-to-return-to-brussels-for-talks-on-ukraine-afghanistan-377207/embed" style="width:100%;max-width:560px;" width="560"></iframe></div>

Blinken's comments came on a day when US President <a href="https://www.wionews.com/topics/joe-biden">Joe Biden </a>is set to formally announce that all US troops will be pulled out from Afghanistan no later than September 11, a senior official has confirmed.&nbsp;

Meanwhile, the US's NATO ally Germany has supported the move of withdrawal by September with its Defence Minister Annegret Kramp-Karrenbauer saying: "We always said: we'll go in together, we'll leave together". &nbsp;

A report in The Times claimed that Britain is also planning to pull out its troops from the country around the same time.

Also read | <a href="https://www.wionews.com/south-asia/biden-set-to-complete-withdrawal-of-remaining-us-troops-from-afghanistan-before-911-anniversary-377408">Biden set to complete withdrawal of remaining US troops from Afghanistan before 9/11 anniversary</a> 
&nbsp;

It said that UK would pull out about 750 troops, citing sources that without the US, Britain would "struggle" because of "a reliance on US bases and infrastructure."

Meanwhile, Turkey has announced an international peace conference in Afghanistan to reach a solution to end nearly 40 years of violence and chaos that has ravaged the nation.&nbsp; 
&nbsp;

US Secretary of State Antony Blinken on Wednesday said that the moment has arrived to bring the foreign troops home, adding that Washington would engage with NATO allies on a "coordinated" pull-out.

US Secretary of State Antony Blinken on Wednesday said that the moment has arrived to bring the foreign troops home, adding that Washington would engage with NATO allies on a "coordinated" pull-out. "Together, we have achieved the goals that we set out to achieve and now it is time to bring our forces home," Blinken was quoted as saying by news agency AFP ahead of talks with NATO nations in Brussels. Watch | Blinken's comments came on a day when US President Joe Biden is set to formally announce that all US troops will be pulled out from Afghanistan no later than September 11, a senior official has confirmed. Meanwhile, the US's NATO ally Germany has supported the move of withdrawal by September with its Defence Minister Annegret Kramp-Karrenbauer saying: "We always said: we'll go in together, we'll leave together". A report in The Times claimed that Britain is also planning to pull out its troops from the country around the same time. Also read | Biden set to complete withdrawal of remaining US troops from Afghanistan before 9/11 anniversary It said that UK would pull out about 750 troops, citing sources that without the US, Britain would "struggle" because of "a reliance on US bases and infrastructure." Meanwhile, Turkey has announced an international peace conference in Afghanistan to reach a solution to end nearly 40 years of violence and chaos that has ravaged the nation.

'Time to bring our forces home': US on Afghan pullout

Thousands of police patrolled the empty streets of the Bangladesh capital on Wednesday as the government enforced a strict nationwide lockdown to combat a deadly new <a href="https://www.wionews.com/topics/coronavirus">coronavirus </a>wave.

Normally jammed with some of Asia's worst gridlock, Dhaka took on the air of a ghost town as officers set up checkpoints across the city of 20 million people to ensure no-one ventured out without a special pass.

Wednesday was the first day of the Bengali new year, when millions normally flock to traditional rallies in major cities, as well as the first day of the Ramadan Muslim fasting month.

But all festivities have been called off for the second year because of the coronavirus threat.

Bangladesh has been swept for the past month by a fresh coronavirus wave that has seen daily infections rise seven-fold and deaths triple.

The South Asian country has recorded roughly 700,000 cases and nearly 10,000 deaths in all.

Tens of thousands of people packed the last trains, buses and ferries before the lockdown came into force at 6:00am (midnight GMT).

A Dhaka police spokesman told AFP said he had only seen "a handful" of people on the streets on the first day of the transport ban, as well as the closure of offices and stores.

For eight days, people are only allowed out to buy food and medicines or for medical emergencies.

Officers are checking online movement passes, issued for the first time.

National police chief Benazir Ahmed ordered all officers to strictly enforce the measure in a call with police chiefs across the country of 168 million people.

"During the government restrictions, no one should step out of their homes unnecessarily," he said.

<h2>Pakistan shutdown&nbsp;</h2>

Coronavirus restrictions have also overshadowed the start of Ramadan in India and Pakistan.

Pandemic curfews are being enforced in many Indian cities as fresh cases again hit new highs, while the number of dead in one day rose above 1,000 for the first time since September.

Pakistan's government has ordered a shutdown of all but essential shops at weekends and the closure of markets at 6.00pm on weekdays.

The poor nation has also been hit by a new wave and authorities fear an acceleration of cases during Ramadan.

Many mosques ignored official pleas to host prayers outside and follow social distancing rules, as Muslims gathered ahead of the first fast.

Ikram Jan, 45, a school teacher in Rawalpindi, said he would pray at home to keep his family safe.

"Most worshippers do not have masks and all of them stand shoulder to shoulder, hundreds of people, that's very dangerous," he said.

More than 730,000 people in Pakistan have been diagnosed with coronavirus, but with limited testing in the country of 220 million people, the true figure is believed to be much higher.

It has recorded more than 15,000 deaths, with 130 reported Wednesday one of the highest daily tolls.

Thousands of police patrolled the empty streets of the Bangladesh capital on Wednesday as the government enforced a strict nationwide lockdown to combat a deadly new coronavirus wave.

Thousands of police patrolled the empty streets of the Bangladesh capital on Wednesday as the government enforced a strict nationwide lockdown to combat a deadly new coronavirus wave. Normally jammed with some of Asia's worst gridlock, Dhaka took on the air of a ghost town as officers set up checkpoints across the city of 20 million people to ensure no-one ventured out without a special pass. Wednesday was the first day of the Bengali new year, when millions normally flock to traditional rallies in major cities, as well as the first day of the Ramadan Muslim fasting month. But all festivities have been called off for the second year because of the coronavirus threat. Bangladesh has been swept for the past month by a fresh coronavirus wave that has seen daily infections rise seven-fold and deaths triple. The South Asian country has recorded roughly 700,000 cases and nearly 10,000 deaths in all. Tens of thousands of people packed the last trains, buses and ferries before the lockdown came into force at 6:00am (midnight GMT). A Dhaka police spokesman told AFP said he had only seen "a handful" of people on the streets on the first day of the transport ban, as well as the closure of offices and stores. For eight days, people are only allowed out to buy food and medicines or for medical emergencies. Officers are checking online movement passes, issued for the first time. National police chief Benazir Ahmed ordered all officers to strictly enforce the measure in a call with police chiefs across the country of 168 million people. "During the government restrictions, no one should step out of their homes unnecessarily," he said. Pakistan shutdown Coronavirus restrictions have also overshadowed the start of Ramadan in India and Pakistan. Pandemic curfews are being enforced in many Indian cities as fresh cases again hit new highs, while the number of dead in one day rose above 1,000 for the first time since September. Pakistan's government has ordered a shutdown of all but essential shops at weekends and the closure of markets at 6.00pm on weekdays. The poor nation has also been hit by a new wave and authorities fear an acceleration of cases during Ramadan. Many mosques ignored official pleas to host prayers outside and follow social distancing rules, as Muslims gathered ahead of the first fast. Ikram Jan, 45, a school teacher in Rawalpindi, said he would pray at home to keep his family safe. "Most worshippers do not have masks and all of them stand shoulder to shoulder, hundreds of people, that's very dangerous," he said. More than 730,000 people in Pakistan have been diagnosed with coronavirus, but with limited testing in the country of 220 million people, the true figure is believed to be much higher. It has recorded more than 15,000 deaths, with 130 reported Wednesday one of the highest daily tolls.

COVID-19: Bangladesh enforces tough lockdown to fight virus

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Zee News Rajasthan

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