Artificial sweeteners have often been called out as unhealthy, and now new research says that one popular sugar substitute increases the risk of heart attack and strokes. Erythritol, an artificial sweetener commonly found in some foods, and a keto-friendly option, is extremely harmful to health, as per a new Cleveland Clinic study. The study found that erythritol makes platelets more active, causing blood clots.&nbsp;

“This research raises some concerns that a standard serving of an erythritol-sweetened food or beverage may acutely stimulate a direct clot-forming effect,” study co-author Dr WH Wilson Tang, research director for Heart Failure and Cardiac Transplantation Medicine at Cleveland Clinic, said. The results of the study were published in the journal Arteriosclerosis, Thrombosis and Vascular Biology on Thursday (August 8).

Surprisingly, the US Food and Drug Administration (FDA) imposes no restrictions on the use of this artificial sweetener. Erythritol has been classified as a GRAS (generally recognised as safe)&nbsp;ingredient by the FDA.

High erythritol levels have in the past been found to make people more prone to developing heart disease. Such people are twice as likely to experience a major cardiac event in three years, the Cleveland Clinic found.&nbsp;

<h2>Risks of artificial sweeteners</h2>

Notably, several people with diabetes often consume artificial sweeteners, and the latest research raises questions about its use.&nbsp;

Also Read:&nbsp;<a href="https://www.wionews.com/entertainment/lifestyle/news-what-is-graves-disease-the-condition-afflicting-star-wars-actress-daisy-ridley-748003">What is Graves' Disease, the condition afflicting Star Wars actress Daisy Ridley</a>

Senior and corresponding author Dr. Stanley Hazen says, “Many professional societies and clinicians routinely recommend that people at high cardiovascular risk — those with obesity, diabetes or metabolic syndrome — consume foods that contain sugar substitutes rather than sugar."&nbsp;

“These findings underscore the importance of further long-term clinical studies to assess the cardiovascular safety of erythritol and other sugar substitutes,” added Hazen. He is the chair of Cardiovascular and Metabolic Sciences in Cleveland Clinic’s Lerner Research Institute and co-section head of Preventive Cardiology.

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WATCH:&nbsp;Ultra-processed food, especially Artificial Sweeteners, linked to depression: Study

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However, the new study took into account healthy adults who consumed erythritol. A significant increase in blood clot formation was recorded in such individuals in comparison to those who used sugar. “Cardiovascular disease builds over time, and heart disease is the leading cause of death globally. We need to make sure the foods we eat aren’t hidden contributors,” Hazen said.

Experts advise consuming natural sugar foods in moderate amounts in place of artificial sweeteners to avoid the health risks posed by them. Recently, Hazen and his team also found that high amounts of xylitol — a sugar alcohol like erythritol, commonly found in sugar-free candy, gums, baked goods and toothpaste — also increase the risk of heart attack and stroke. 
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Artificial sweeteners have often been called out as unhealthy, and now new research says that one popular sugar substitute increases the risk of heart attack and strokes.

Artificial sweeteners have often been called out as unhealthy, and now new research says that one popular sugar substitute increases the risk of heart attack and strokes. Erythritol, an artificial sweetener commonly found in some foods, and a keto-friendly option, is extremely harmful to health, as per a new Cleveland Clinic study. The study found that erythritol makes platelets more active, causing blood clots. “This research raises some concerns that a standard serving of an erythritol-sweetened food or beverage may acutely stimulate a direct clot-forming effect,” study co-author Dr WH Wilson Tang, research director for Heart Failure and Cardiac Transplantation Medicine at Cleveland Clinic, said. The results of the study were published in the journal Arteriosclerosis, Thrombosis and Vascular Biology on Thursday (August 8). Surprisingly, the US Food and Drug Administration (FDA) imposes no restrictions on the use of this artificial sweetener. Erythritol has been classified as a GRAS (generally recognised as safe) ingredient by the FDA. High erythritol levels have in the past been found to make people more prone to developing heart disease. Such people are twice as likely to experience a major cardiac event in three years, the Cleveland Clinic found. Risks of artificial sweeteners Notably, several people with diabetes often consume artificial sweeteners, and the latest research raises questions about its use. Also Read: What is Graves' Disease, the condition afflicting Star Wars actress Daisy Ridley Senior and corresponding author Dr. Stanley Hazen says, “Many professional societies and clinicians routinely recommend that people at high cardiovascular risk — those with obesity, diabetes or metabolic syndrome — consume foods that contain sugar substitutes rather than sugar." “These findings underscore the importance of further long-term clinical studies to assess the cardiovascular safety of erythritol and other sugar substitutes,” added Hazen. He is the chair of Cardiovascular and Metabolic Sciences in Cleveland Clinic’s Lerner Research Institute and co-section head of Preventive Cardiology. WATCH: Ultra-processed food, especially Artificial Sweeteners, linked to depression: Study × However, the new study took into account healthy adults who consumed erythritol. A significant increase in blood clot formation was recorded in such individuals in comparison to those who used sugar. “Cardiovascular disease builds over time, and heart disease is the leading cause of death globally. We need to make sure the foods we eat aren’t hidden contributors,” Hazen said. Experts advise consuming natural sugar foods in moderate amounts in place of artificial sweeteners to avoid the health risks posed by them. Recently, Hazen and his team also found that high amounts of xylitol — a sugar alcohol like erythritol, commonly found in sugar-free candy, gums, baked goods and toothpaste — also increase the risk of heart attack and stroke.

Keto-friendly artificial sweetener linked to heart attack and stroke

A diet high in ultra-processed food (UPF), particularly artificial sweeteners, has been linked to increased depression risk, new data from the Nurses Health Study II (NHS II) suggest.

Ultra-processed food, especially Artificial Sweeteners linked to depression: Study

Written by Ishit Saurabh Pilani

Artificial sweeteners are sugar substitutes that are derived from naturally occurring substances, such as a plant, herb or sugar itself. Artificial sweeteners are intense sweeteners and therefore are required in a lesser amount than sugar.&nbsp; 
 
Artificial sweeteners are used in processed foods. These include soft drinks and other beverages, baked goods, candy, puddings and yoghurts, canned foods and sweet spreads like jam. One of the most commonly known artificial sweeteners is Aspartame.&nbsp; 
 
Aspartame has been in the news lately because of a recent report by the International Agency for Research on Cancer (IARC), the World Health Organization's (WHO) cancer research arm. The report suggests that aspartame is set to be declared a possible carcinogen next month.&nbsp; 
 
In light of these recent developments, it is important to know how aspartame affects our life. Here are 5 common products that have aspartame. 
 
1. Diet Soda: Diet sodas, such as Diet Coke, Diet Pepsi, and Coke Zero, contain aspartame as a sugar substitute. 
 
2. Sugar-Free Gum: Aspartame is commonly found in sugar-free chewing gums like Trident, Orbit, and Extra. 
 
3. Low-Calorie Yogurt: Certain low-calorie or "light" yoghurt brands may use aspartame as a sweetener. Always check the ingredient list to determine if aspartame is included. 
 
4. Sugar-Free Pudding: Some sugar-free pudding mixes may contain aspartame to provide sweetness without the use of sugar.

5. Sugar-Free Jellies and Syrups: Certain sugar-free jellies, jams, and syrups, used as toppings or fillings, may use aspartame as a sugar substitute. 
 
Aspartame can be found in various other products labelled as "sugar-free" or "diet." It's always a good practice to read the ingredient list or look for labels indicating the presence of aspartame if you are trying to avoid it or have specific dietary requirements.&nbsp;It is important to note that individual responses to aspartame may vary. However, in today's day and age, it is important to lead a healthy lifestyle.&nbsp; 
 
Try to avoid consuming food with artificial sweeteners. Instead, eat healthy and fresh. There are ready-to-eat healthy meals also available which are convenient and quick.&nbsp; 
 
The larger question here is should we just believe in what the bigger food lobbyists make us believe? They have the money to influence. Research is always sponsored.&nbsp; 
 
Cross-check your research from multiple references. Know who has sponsored the research. It matters. Concentrate on your health and know what is good for you. Anything which is artificial or made with chemicals can’t be good for health. Read the labels and ask the right questions. Understand what you are eating. Don’t fall for marketing gimmicks. Besides this, read the details of the ingredients before buying a product. You are what you eat so eat fresh and natural produce.&nbsp; 
 
This report with aspartame also sheds light on the accountability of large food corporations and government agencies. While the consumer needs to do due diligence, a share of the responsibility also falls on the manufacturers and authorities to have stricter codes of conduct in place.

- The author is the co-founder of Organic Foods

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Written by Ishit Saurabh Pilani Artificial sweeteners are sugar substitutes that are derived from naturally occurring substances, such as a plant, herb or sugar itself.

Written by Ishit Saurabh Pilani Artificial sweeteners are sugar substitutes that are derived from naturally occurring substances, such as a plant, herb or sugar itself. Artificial sweeteners are intense sweeteners and therefore are required in a lesser amount than sugar. Artificial sweeteners are used in processed foods. These include soft drinks and other beverages, baked goods, candy, puddings and yoghurts, canned foods and sweet spreads like jam. One of the most commonly known artificial sweeteners is Aspartame. Aspartame has been in the news lately because of a recent report by the International Agency for Research on Cancer (IARC), the World Health Organization's (WHO) cancer research arm. The report suggests that aspartame is set to be declared a possible carcinogen next month. In light of these recent developments, it is important to know how aspartame affects our life. Here are 5 common products that have aspartame. 1. Diet Soda: Diet sodas, such as Diet Coke, Diet Pepsi, and Coke Zero, contain aspartame as a sugar substitute. 2. Sugar-Free Gum: Aspartame is commonly found in sugar-free chewing gums like Trident, Orbit, and Extra. 3. Low-Calorie Yogurt: Certain low-calorie or "light" yoghurt brands may use aspartame as a sweetener. Always check the ingredient list to determine if aspartame is included. 4. Sugar-Free Pudding: Some sugar-free pudding mixes may contain aspartame to provide sweetness without the use of sugar. 5. Sugar-Free Jellies and Syrups: Certain sugar-free jellies, jams, and syrups, used as toppings or fillings, may use aspartame as a sugar substitute. Aspartame can be found in various other products labelled as "sugar-free" or "diet." It's always a good practice to read the ingredient list or look for labels indicating the presence of aspartame if you are trying to avoid it or have specific dietary requirements. It is important to note that individual responses to aspartame may vary. However, in today's day and age, it is important to lead a healthy lifestyle. Try to avoid consuming food with artificial sweeteners. Instead, eat healthy and fresh. There are ready-to-eat healthy meals also available which are convenient and quick. The larger question here is should we just believe in what the bigger food lobbyists make us believe? They have the money to influence. Research is always sponsored. Cross-check your research from multiple references. Know who has sponsored the research. It matters. Concentrate on your health and know what is good for you. Anything which is artificial or made with chemicals can’t be good for health. Read the labels and ask the right questions. Understand what you are eating. Don’t fall for marketing gimmicks. Besides this, read the details of the ingredients before buying a product. You are what you eat so eat fresh and natural produce. This report with aspartame also sheds light on the accountability of large food corporations and government agencies. While the consumer needs to do due diligence, a share of the responsibility also falls on the manufacturers and authorities to have stricter codes of conduct in place. - The author is the co-founder of Organic Foods WATCH WION LIVE HERE You can now write for wionews.com and be a part of the community. Share your stories and opinions with us here.

Why you must avoid sweeteners like Aspartame

Cutting on sugar can be a great challenge for someone trying to lose weight. The change in taste in our usual comfort foods can be tough to handle. Many people opt for artificial sweeteners to try to calm down the taste buds. But now World Health Organisation has clearly said that artificial sweeteners do not provide long-term benefit in reducing body fat in adults or children.

The WHO has released a new guideline in accordance to which artificial sweeteners are not just without benefits but they also increase the risk of type-2 diabetes, cardiovascular disease and even death.

Francesco Branca, Director for Nutrition and Food Safety at WHO said that people need to consider other ways to reduce free sugars intake.

"Replacing free sugars with non-sugar sweeteners (NSS) does not help with weight control in the long term. People need to consider other ways to reduce free sugars intake, such as consuming food with naturally occurring sugars, like fruit, or unsweetened food and beverages,” said Branca.

"NSS are not essential dietary factors and have no nutritional value. People should reduce the sweetness of the diet altogether, starting early in life, to improve their health."

Branca was quoted on the official website of WHO.

Common NSS include aspartame, advantame, sucralose, saccharin, neotame, acesulfame K, cyclamates, stevia and stevia derivatives.

However, WHO noted that its recommendation does not apply to personal care and hygiene product that contain non-sugar sweeteners (NSS). This means that NSS in products like skin cream, toothpaste, medications or low-calorie sugars and sugar alcohols (polyols) do not pose the threat WHO has warned about.

Also Read | <a href="https://www.wionews.com/science/research-unmasks-shocking-toll-social-isolation-has-on-human-body-592437">Research unmasks shocking toll social isolation has on human body</a>

"Because the link observed in the evidence between NSS and disease outcomes might be confounded by baseline characteristics of study participants and complicated patterns of NSS use, the recommendation has been assessed as conditional, following WHO processes for developing guidelines. This signals that policy decisions based on this recommendation may require substantive discussion in specific country contexts, linked for example to the extent of consumption in different age groups," says WHO on its website.

Also Read | <a href="https://www.wionews.com/science/kids-using-smartphones-may-face-mental-health-issues-as-adults-reveals-study-592851">Kids using smartphones may face some serious mental health issues as adults, reveals study</a>

“This new guideline is based on a thorough assessment of the latest scientific literature, and it emphasises that the use of artificial sweeteners is not a good strategy for achieving weight loss by reducing dietary energy intake,” said nutrition researcher Ian Johnson, emeritus fellow at Quadram Institute Bioscience. He was quoted by CNN.&nbsp;

So for those of us who were being sneaky and at the same feeling morally superior, it' s time to go back to basics and cut sugar completely!

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Cutting on sugar can be a great challenge for someone trying to lose weight. The change in taste in our usual comfort foods can be tough to handle. Many people opt for artificial sweeteners to try to calm down the taste buds.

Cutting on sugar can be a great challenge for someone trying to lose weight. The change in taste in our usual comfort foods can be tough to handle. Many people opt for artificial sweeteners to try to calm down the taste buds. But now World Health Organisation has clearly said that artificial sweeteners do not provide long-term benefit in reducing body fat in adults or children. The WHO has released a new guideline in accordance to which artificial sweeteners are not just without benefits but they also increase the risk of type-2 diabetes, cardiovascular disease and even death. Francesco Branca, Director for Nutrition and Food Safety at WHO said that people need to consider other ways to reduce free sugars intake. "Replacing free sugars with non-sugar sweeteners (NSS) does not help with weight control in the long term. People need to consider other ways to reduce free sugars intake, such as consuming food with naturally occurring sugars, like fruit, or unsweetened food and beverages,” said Branca. "NSS are not essential dietary factors and have no nutritional value. People should reduce the sweetness of the diet altogether, starting early in life, to improve their health." Branca was quoted on the official website of WHO. Common NSS include aspartame, advantame, sucralose, saccharin, neotame, acesulfame K, cyclamates, stevia and stevia derivatives. However, WHO noted that its recommendation does not apply to personal care and hygiene product that contain non-sugar sweeteners (NSS). This means that NSS in products like skin cream, toothpaste, medications or low-calorie sugars and sugar alcohols (polyols) do not pose the threat WHO has warned about. Also Read | Research unmasks shocking toll social isolation has on human body "Because the link observed in the evidence between NSS and disease outcomes might be confounded by baseline characteristics of study participants and complicated patterns of NSS use, the recommendation has been assessed as conditional, following WHO processes for developing guidelines. This signals that policy decisions based on this recommendation may require substantive discussion in specific country contexts, linked for example to the extent of consumption in different age groups," says WHO on its website. Also Read | Kids using smartphones may face some serious mental health issues as adults, reveals study “This new guideline is based on a thorough assessment of the latest scientific literature, and it emphasises that the use of artificial sweeteners is not a good strategy for achieving weight loss by reducing dietary energy intake,” said nutrition researcher Ian Johnson, emeritus fellow at Quadram Institute Bioscience. He was quoted by CNN. So for those of us who were being sneaky and at the same feeling morally superior, it' s time to go back to basics and cut sugar completely! You can now write for wionews.com and be a part of the community. Share your stories and opinions with us here. WATCH WION LIVE HERE ×

Using sugar substitutes for weight loss? WHO has a warning for you

Aerated drinks, ice creams, yogurts, even the most ordinary chewing gum, are full of artificial sweeteners which can cause strokes, blood clots, and believe it or not... it can also result in death. Do not let artificial sweeteners turn your life sour. Molly Gambhir reports.

Gravitas: Artificial sweeteners or killer sweeteners

A study by French researchers has established that artificial sweeteners increase the risk of heart problems. As part of a study, they tracked 103,000 adults for nine years and found that people who consumed calorie-free sweeteners every day had a nine&nbsp;per cent higher risk of heart disease, The Times UK reported.

The chances of suffering a stroke rose for those who ate or drank aspartame, an ingredient used in low-sugar fizzy drinks, and they were found to be 23 per cent more likely to have a stroke.

Also Read |&nbsp;<a href="https://www.wionews.com/science/artificial-sweeteners-increase-risk-of-cancer-by-up-to-13-says-study-465373">Artificial sweeteners increase risk of cancer by up to 13%, says study</a>

The participants consumed average of 43mg of sweeteners a day, the equivalent of one packet of table-top sweetener or 100ml of diet soda.

Artificial sweeteners contain sucralose and aspartame, a white odourless powder 200 times sweeter than sugar. While they don't have any calories, artificial sweeteners have been found to be harmful to health. The latest research published in the British Medical Journal proves the need to cut back on the consumption of diet drinks and foods.

The study says, “These food additives, consumed daily by millions of people and present in thousands of foods and drinks, should not be considered a healthy and safe alternative to sugar.”

<a href="https://www.wionews.com/videos/study-diet-soda-increases-risk-of-heart-disease-artificial-sweeteners-in-diet-drinks-harmful-514058">WATCH |&nbsp;Study: Diet soda increases risk of heart disease; Artificial sweeteners in diet drinks harmful</a>

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Experts believe that sweeteners can hinder with the body’s ability to tolerate glucose, interfere with levels of hormones such as insulin and reduce the health of the gut microbiome. The World Health Organisation is also evaluating these chemicals to gain a better understanding.&nbsp;

There are others who say that there is no need to panic and more studies are needed to gain an overall perspective. However, it is still wise to swap fizzy drinks for water and eat more heart-healthy foods, like lentils, nuts and seeds, fruits, vegetables and wholegrains.

(With inputs from agencies)

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A study by French researchers has established that artificial sweeteners increase the risk of heart problems. As part of a study, they tracked 103,000 adults for nine years and found that people who consumed calorie-free sweeteners every day had a nine per cent higher risk of heart disease, The Times UK reported.

A study by French researchers has established that artificial sweeteners increase the risk of heart problems. As part of a study, they tracked 103,000 adults for nine years and found that people who consumed calorie-free sweeteners every day had a nine per cent higher risk of heart disease, The Times UK reported. The chances of suffering a stroke rose for those who ate or drank aspartame, an ingredient used in low-sugar fizzy drinks, and they were found to be 23 per cent more likely to have a stroke. Also Read | Artificial sweeteners increase risk of cancer by up to 13%, says study The participants consumed average of 43mg of sweeteners a day, the equivalent of one packet of table-top sweetener or 100ml of diet soda. Artificial sweeteners contain sucralose and aspartame, a white odourless powder 200 times sweeter than sugar. While they don't have any calories, artificial sweeteners have been found to be harmful to health. The latest research published in the British Medical Journal proves the need to cut back on the consumption of diet drinks and foods. The study says, “These food additives, consumed daily by millions of people and present in thousands of foods and drinks, should not be considered a healthy and safe alternative to sugar.” WATCH | Study: Diet soda increases risk of heart disease; Artificial sweeteners in diet drinks harmful × Experts believe that sweeteners can hinder with the body’s ability to tolerate glucose, interfere with levels of hormones such as insulin and reduce the health of the gut microbiome. The World Health Organisation is also evaluating these chemicals to gain a better understanding. There are others who say that there is no need to panic and more studies are needed to gain an overall perspective. However, it is still wise to swap fizzy drinks for water and eat more heart-healthy foods, like lentils, nuts and seeds, fruits, vegetables and wholegrains. (With inputs from agencies) WATCH WION LIVE HERE:

Diet soda significantly ups your chances of suffering a stroke, says study

Studies claim artificial sweeteners can increase your risk of diabetes, they can also make you gain weight. But weren't artificial sweeteners supposed to do the opposite? These products were endorsed as sweet alternatives to sugar. Palki Sharma tells you.

Gravitas | Study: Artificial sweeteners can cause diabetes

A new peer-reviewed research&nbsp;has revealed that artificial sweeteners may&nbsp;actually increase sugar levels in the body.

Highlighting that it is no longer safe to assume that artificial sweeteners are not bad for people's health, immunologist Professor&nbsp;Eran Elinav of the Weizmann Institute of Science raised concerns about their consumption.

Consuming saccharin and sucralose harms the ability of healthy adults to dispose of glucose in their bodies, says the study published in the journal Cell.

Eight years ago, a study on rodents rang alarm bells about artificial sweeteners and the current study has reiterated those fears.

“They may have directly contributed to enhancing the exact epidemic that they themselves were intended to fight,” Elinav told The Times of Israel.

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The assumption that sweeteners provide a harmless hit of sweetness without any health cost is harmful, according to Elinav.

While saccharin and sucralose appeared to significantly impair glucose response, when they were combined with aspartame, and stevia then all four of them caused changes in the gut bacteria.

“We found that the gut microbe composition and function changes in response to consumption of all four sweeteners, meaning that they are not inert to the human body,” said Elinav.

When the faeces from some of the people were transplanted into rodents during the experiment, it bred to have no bacteria of their own.

Sweeteners reduced the ability to dispose of glucose in mice with faeces from people whose glucose tolerance was hit hardest by sweeteners.

Changing the microbiome can impact glucose tolerance, and this strengthened the scientist's theory that sweeteners are affecting gut bacteria.

(With inputs from agencies)

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A new peer-reviewed research has revealed that artificial sweeteners may actually increase sugar levels in the body. Highlighting that it is no longer safe to assume that artificial sweeteners are not bad for people's health, immunologist Professor Eran Elinav of the Weizmann Institute of Science raised concerns about their consumption.

A new peer-reviewed research has revealed that artificial sweeteners may actually increase sugar levels in the body. Highlighting that it is no longer safe to assume that artificial sweeteners are not bad for people's health, immunologist Professor Eran Elinav of the Weizmann Institute of Science raised concerns about their consumption. Consuming saccharin and sucralose harms the ability of healthy adults to dispose of glucose in their bodies, says the study published in the journal Cell. Eight years ago, a study on rodents rang alarm bells about artificial sweeteners and the current study has reiterated those fears. “They may have directly contributed to enhancing the exact epidemic that they themselves were intended to fight,” Elinav told The Times of Israel. × The assumption that sweeteners provide a harmless hit of sweetness without any health cost is harmful, according to Elinav. While saccharin and sucralose appeared to significantly impair glucose response, when they were combined with aspartame, and stevia then all four of them caused changes in the gut bacteria. “We found that the gut microbe composition and function changes in response to consumption of all four sweeteners, meaning that they are not inert to the human body,” said Elinav. When the faeces from some of the people were transplanted into rodents during the experiment, it bred to have no bacteria of their own. Sweeteners reduced the ability to dispose of glucose in mice with faeces from people whose glucose tolerance was hit hardest by sweeteners. Changing the microbiome can impact glucose tolerance, and this strengthened the scientist's theory that sweeteners are affecting gut bacteria. (With inputs from agencies) Watch WION's live TV here: ×

New study shows artificial sweeteners may increase sugar levels, affect gut health

In a study published in a journal, researchers in Israel say that artificial sweeteners should no longer be assumed to be safe and good for the health. Though these products are often advertised to have low calorie, the study finds that it may actually increase the sugar level in the body.

Artificial sweeteners may increase sugar levels in body, impair ability to dispose glucose

Some artificial sweeteners seem to have an effect on how the body metabolises drugs like antibiotics, antidepressants and antivirals, media reports said citing a study. The research was carried out by the Medical College of Wisconsin in the US last month. Well, medicines usually work when taken at the right time and in the apt way. But the research has revealed that external factors like some artificial sweeteners can also have an effect on it. In the study, the artificial sweeteners, sucralose and acesulfame potassium, seem to have disrupted the function of a protein in the liver, which looks to remove toxins and drugs from the body. The research was just preliminary work and "more research is needed", the authors of the lab-based study said. &nbsp;

Not just this, citrus fruit like grapefruit can also disrupt the absorption of around 85 different medicines. These may include statins, antidepressants, etc. This happens as the fruit contains compounds like furanocoumarins. This can interfere with an enzyme in our body and break down these medicines. &nbsp;

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In normal conditions, this enzyme looks to keep a check on the amount of the drug, which enters your blood, Simon Maxwell, professor, clinical pharmacology, Edinburgh University told Daily Mail. &nbsp;

"But if at the same time you drink grapefruit juice— or eat the fruit — the furanocoumarins stop this enzyme doing its job. This can be important for a number of widely prescribed drugs. This interaction partly occurs in the gut, enabling increased absorption, but also — significantly — in the liver, preventing it from progressively removing the drug in the hours after absorption. Together, this means that overall exposure to the drug can be significantly increased, resulting in toxic effects," Maxwell said. &nbsp;

(With inputs from agencies) &nbsp;&nbsp;

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Some artificial sweeteners seem to have an effect on how the body metabolises drugs like antibiotics, antidepressants and antivirals, media reports said citing a study.

Some artificial sweeteners seem to have an effect on how the body metabolises drugs like antibiotics, antidepressants and antivirals, media reports said citing a study. The research was carried out by the Medical College of Wisconsin in the US last month. Well, medicines usually work when taken at the right time and in the apt way. But the research has revealed that external factors like some artificial sweeteners can also have an effect on it. In the study, the artificial sweeteners, sucralose and acesulfame potassium, seem to have disrupted the function of a protein in the liver, which looks to remove toxins and drugs from the body. The research was just preliminary work and "more research is needed", the authors of the lab-based study said. Not just this, citrus fruit like grapefruit can also disrupt the absorption of around 85 different medicines. These may include statins, antidepressants, etc. This happens as the fruit contains compounds like furanocoumarins. This can interfere with an enzyme in our body and break down these medicines. WATCH WION LIVE HERE In normal conditions, this enzyme looks to keep a check on the amount of the drug, which enters your blood, Simon Maxwell, professor, clinical pharmacology, Edinburgh University told Daily Mail. "But if at the same time you drink grapefruit juice— or eat the fruit — the furanocoumarins stop this enzyme doing its job. This can be important for a number of widely prescribed drugs. This interaction partly occurs in the gut, enabling increased absorption, but also — significantly — in the liver, preventing it from progressively removing the drug in the hours after absorption. Together, this means that overall exposure to the drug can be significantly increased, resulting in toxic effects," Maxwell said. (With inputs from agencies) You can now write for wionews.com and be a part of the community. Share your stories and opinions with us here. ×

Some artificial sweeteners, citrus fruits can affect how body metabolises drugs, find experts

Some artificial sweeteners can spike the risk of contracting cancer, a study has said. The alternatives to sugar generally used in food increase the risk by up to 13 per cent. The experts of French National Institute for Health and Medical Research and Sorbonne Paris Nord University came up with the finding

Artificial sweeteners can increase risk of cancer by up to 13%, says study

Some artificial sweeteners may not be good for health and could spike the risk of contracting cancer, a large-scale study has said. &nbsp;&nbsp;

These alternatives to sugar, which are used in food and drinks, may hike the risk by up to 13 per cent. &nbsp;

The experts of the French National Institute for Health and Medical Research, and Sorbonne Paris Nord University analysed data and came up to the conclusion that the risk for breast cancer and obesity-related cancers increases with these food materials. &nbsp;

Also Read:&nbsp;<a href="https://www.wionews.com/science/to-show-coolness-orangutans-like-humans-use-slang-says-study-464507" hreflang="en">To show coolness, orangutans like humans use slang, says study</a>

The data for 102,865 French adults was examined in the new study, which was published in PLOS Medicine. &nbsp;

In the research, people self-reported their diet, medical history, lifestyle habits and other data. The researchers looked at artificial sweetener intake in their dietary records and the diagnoses of cancer. &nbsp;

The findings showed that people who consumed larger quantities, like 79 mg per day, of artificial sweeteners had a 13 per cent more risk of contracting cancer in comparison to people avoiding them. &nbsp;

Also Read:&nbsp;<a href="https://www.wionews.com/science/recycled-plastic-bottles-pass-more-harmful-chemicals-into-contents-than-new-ones-warn-researchers-463736" hreflang="en">Recycled plastic bottles pass more harmful chemicals into contents than new ones, warn researchers</a>

As per the scientists, higher risks were observed for breast cancer and obesity-related cancers. &nbsp;&nbsp;

The researchers said, "Our findings do not support the use of artificial sweeteners as safe alternatives for sugar in foods or beverages and provide important and novel information to address the controversies about their potential adverse health effects.” &nbsp;&nbsp;

(With inputs from agencies)&nbsp;

Some artificial sweeteners may not be good for health and could spike the risk of contracting cancer, a large-scale study has said. These alternatives to sugar, which are used in food and drinks, may hike the risk by up to 13 per cent.

Some artificial sweeteners may not be good for health and could spike the risk of contracting cancer, a large-scale study has said. These alternatives to sugar, which are used in food and drinks, may hike the risk by up to 13 per cent. The experts of the French National Institute for Health and Medical Research, and Sorbonne Paris Nord University analysed data and came up to the conclusion that the risk for breast cancer and obesity-related cancers increases with these food materials. Also Read: To show coolness, orangutans like humans use slang, says study The data for 102,865 French adults was examined in the new study, which was published in PLOS Medicine. In the research, people self-reported their diet, medical history, lifestyle habits and other data. The researchers looked at artificial sweetener intake in their dietary records and the diagnoses of cancer. The findings showed that people who consumed larger quantities, like 79 mg per day, of artificial sweeteners had a 13 per cent more risk of contracting cancer in comparison to people avoiding them. Also Read: Recycled plastic bottles pass more harmful chemicals into contents than new ones, warn researchers As per the scientists, higher risks were observed for breast cancer and obesity-related cancers. The researchers said, "Our findings do not support the use of artificial sweeteners as safe alternatives for sugar in foods or beverages and provide important and novel information to address the controversies about their potential adverse health effects.” (With inputs from agencies)

Artificial sweeteners increase risk of cancer by up to 13%, says study

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