Manchester United fought back to overpower West Ham United 3-1 and reach the FA Cup quarter-finals as Premier League Tottenham Hotspur and Southampton suffered shock defeats on Wednesday.

Manchester United fight back vs  West Ham to enter FA Cup QFs, Spurs and Southampton out

Ruben Selles was named as the new manager of the Premier League strugglers Southampton on Friday, February 24. The 39-year-old will now manage the team until the end of the season.

Who is Ruben Selles? New Spaniard manager of the Southampton club- Know 10 things about his coaching career

Although Cristiano Ronaldo was shackled to the sidelines for the second consecutive time in Manchester United's most recent clash against Southampton, he did not let his frustrations become apparent as he was seen in a jovial mood ahead of the match.

Watch: Cristiano Ronaldo hilariously pranks Rio Ferdinand ahead of Southampton clash

Sadio Mane's first-half header and a late effort by Thiago earned Liverpool an unconvincing 2-0 win at home to Southampton on Saturday to keep Juergen Klopp's side in the hunt for a top-four finish in the Premier League.

Sadio Mane seals win for Liverpool to keep top-four hopes alive

Beaten Tottenham Hotspur suffered a double injury blow in the 1-0 defeat at Southampton on Wednesday with Harry Kane and Tanguy Ndombele both forced off at St Mary's.

Premier League: Tottenham suffer Kane injury blow

Sergio Aguero scored twice as Manchester City's much-changed side strolled to a 3-1 League Cup fourth round win on Tuesday over Southampton who seemed relieved to avoid a repeat of their nine-goal thrashing by Leicester City four days earlier.

Manchester City stroll to League Cup win over Southampton

Southampton have promised to ban supporters involved in mocking the death of Emiliano Sala by making aeroplane gestures during their match at home to Cardiff City on Saturday.

Southampton vows to ban fans who mocked Emiliano Sala's death

Ross Barkley scored his first goal for Maurizio Sarri's unbeaten Chelsea to help move them provisionally top of the Premier League in a 3-0 win at Southampton on Sunday.

Impressive Barkley drives Chelsea past Southampton

Shane Long joined Southampton from Hull City in 2014 and was instrumental in helping them to qualify for Europa League

Long signs new four-year deal with Southampton

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Manchester United fight back vs West Ham to enter FA Cup QFs, Spurs and Southampton out