<p>Tasmanian tiger, a marsupial apex predator, went extinct nearly a century ago. Now, scientists are closer than ever to reviving the animal through genome sequencing in a process similar to the fictional revival of dinosaurs in <em>Jurassic Park</em>.</p>

<p>The carnivore's genome has been reconstructed with 99.9% accuracy, the&nbsp;latest breakthrough in the years-long 'de-extinction' project.&nbsp;</p>

<p>There are only 45 gaps left to fill in the genome sequencing, which was made possible from a chance discovery of a head of the animal pickled in a jar in Australia some 110 years ago.</p>

<p><strong>Watch: Gravitas: Scientists extract RNA from extinct Tasmanian tiger</strong></p>

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<p>Behind this mammoth task (pardon the pun) is Colossal Biosciences, a Texas-based firm that is also in the process of reviving the woolly mammoth and the dodo, a flightless bird that also went extinct over a century ago.</p>

<h2><strong>What happened to tasmanian tiger? An icon of extinction</strong></h2>

<p>The Tasmanian tiger or thylacine roamed the forests of Tasmania in Australia from where it takes its name.</p>

<p>Once a critical link in the ecosystem of Tasmania,&nbsp;they officially went extinct in 1936 after the last animal died at&nbsp;Beaumaris Zoo in Tasmania's Hobart.</p>

<p>Colossal teased that a major update is coming soon on the revival of the animal,&nbsp;whose scientific name is Thylacinus cynocephalus,</p>

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<p dir="ltr" lang="en">At <a href="https://twitter.com/sxswsydney?ref_src=twsrc%5Etfw">@sxswsydney</a> with <a href="https://twitter.com/AJ_Pask?ref_src=twsrc%5Etfw">@AJ_Pask</a>, and <a href="https://twitter.com/Hemsdog?ref_src=twsrc%5Etfw">@Hemsdog</a> sharing an update on our thylacine de-extinction project 🐅<br />
<br />
When an apex predator goes extinct, it has a cascading effect on the ecosystem. Prey populations go unchecked, diseases run rampant, plant life suffers—everything is thrown… <a href="https://t.co/ob8tP0A5lN">pic.twitter.com/ob8tP0A5lN</a></p>
— Colossal Biosciences® (@colossal) <a href="https://twitter.com/colossal/status/1847044711070003532?ref_src=twsrc%5Etfw">October 17, 2024</a></blockquote>
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<p><a href="https://www.wionews.com/science/did-woolly-mammoth-go-extinct-because-of-a-blocked-nose-study-says-they-did-764159"><strong>Also read: Did woolly mammoth go extinct because of a blocked nose? Study says they did</strong></a></p>

<h2><strong>A miracle in the making: How a head pickled in a jar could bring back extinct Tasmanian tiger </strong></h2>

<p>The Tasmanian tiger head recovered from the jar in Australia still had RNA molecules, which is crucial for rebuilding the genome. Using samples from the head, most of the DNA of the animal has been sequenced along with strands of RNA.</p>

<p>It was nothing short of a miracle, according to scientists involved in the project who spoke to media.</p>

<p><strong><a href="https://www.wionews.com/science/in-jurassic-park-style-extinct-dodo-to-be-revived-scientists-say-667977">Also read: In 'Jurassic Park' style, extinct flightless bird dodo to be revived. Scientists say...</a></strong><br />
<br />
“This was the miracle that happened with this specimen. It blew my mind,” said&nbsp;Prof Andrew Pask, the head of the thylacine integrated genetic restoration research or Tigrr lab at the University of Melbourne.</p>

<p>“It was literally a head in a bucket of ethanol in the back of a cupboard that had just been dumped there with all the skin removed, and been sitting there for about 110 years,” The Guardian quoted Pask as saying. “It was pretty putrid, a completely gruesome sight. People had chopped large chunks off it.”&nbsp;</p>

<h2><strong>Genome sequencing: A method of 'de-extinction' of the world's lost species?</strong></h2>

<p>“You absolutely can get a phenomenal genome from old samples,” Pesk told LiveScience.</p>

<p>DNA is the genetic material that is the fundamental building block of life. A genome is a full set of DNA that gives the unique charecteristsic to each organism. Genome contains the chemical information for development, growth and functioning of living beings.<br />
<br />
As Pesk puts it, genomes provide 'the full blueprint for de-extincting this species'.</p>

<p>Getting the complete genome sequencing at very high quality is a huge help to the efforts to revive extinct species, he said.</p>

<p><em>(With inputs from agencies)</em><br />
&nbsp;</p>


Tasmanian tiger, a marsupial apex predator, went extinct nearly a century ago. Now, scientists are closer than ever to reviving the animal through genome sequencing in a process similar to the fictional revival of dinosaurs in Jurassic Park.

Tasmanian tiger, a marsupial apex predator, went extinct nearly a century ago. Now, scientists are closer than ever to reviving the animal through genome sequencing in a process similar to the fictional revival of dinosaurs in Jurassic Park. The carnivore's genome has been reconstructed with 99.9% accuracy, the latest breakthrough in the years-long 'de-extinction' project. There are only 45 gaps left to fill in the genome sequencing, which was made possible from a chance discovery of a head of the animal pickled in a jar in Australia some 110 years ago. Watch: Gravitas: Scientists extract RNA from extinct Tasmanian tiger × Behind this mammoth task (pardon the pun) is Colossal Biosciences, a Texas-based firm that is also in the process of reviving the woolly mammoth and the dodo, a flightless bird that also went extinct over a century ago. What happened to tasmanian tiger? An icon of extinction The Tasmanian tiger or thylacine roamed the forests of Tasmania in Australia from where it takes its name. Once a critical link in the ecosystem of Tasmania, they officially went extinct in 1936 after the last animal died at Beaumaris Zoo in Tasmania's Hobart. Colossal teased that a major update is coming soon on the revival of the animal, whose scientific name is Thylacinus cynocephalus, At @sxswsydney with @AJ_Pask, and @Hemsdog sharing an update on our thylacine de-extinction project 🐅 When an apex predator goes extinct, it has a cascading effect on the ecosystem. Prey populations go unchecked, diseases run rampant, plant life suffers—everything is thrown… pic.twitter.com/ob8tP0A5lN — Colossal Biosciences® (@colossal) October 17, 2024 × Also read: Did woolly mammoth go extinct because of a blocked nose? Study says they did A miracle in the making: How a head pickled in a jar could bring back extinct Tasmanian tiger The Tasmanian tiger head recovered from the jar in Australia still had RNA molecules, which is crucial for rebuilding the genome. Using samples from the head, most of the DNA of the animal has been sequenced along with strands of RNA. It was nothing short of a miracle, according to scientists involved in the project who spoke to media. Also read: In 'Jurassic Park' style, extinct flightless bird dodo to be revived. Scientists say... “This was the miracle that happened with this specimen. It blew my mind,” said Prof Andrew Pask, the head of the thylacine integrated genetic restoration research or Tigrr lab at the University of Melbourne. “It was literally a head in a bucket of ethanol in the back of a cupboard that had just been dumped there with all the skin removed, and been sitting there for about 110 years,” The Guardian quoted Pask as saying. “It was pretty putrid, a completely gruesome sight. People had chopped large chunks off it.” Genome sequencing: A method of 'de-extinction' of the world's lost species? “You absolutely can get a phenomenal genome from old samples,” Pesk told LiveScience. DNA is the genetic material that is the fundamental building block of life. A genome is a full set of DNA that gives the unique charecteristsic to each organism. Genome contains the chemical information for development, growth and functioning of living beings. As Pesk puts it, genomes provide 'the full blueprint for de-extincting this species'. Getting the complete genome sequencing at very high quality is a huge help to the efforts to revive extinct species, he said. (With inputs from agencies)

Tasmanian tiger that went extinct may come back soon, thanks to a head in a bucket of ethanol

<p>India has reported a total of 22 cases of the COVID-19 subvariant JN.1, prompting health authorities to implement precautionary measures to curb further spread. While all reported cases exhibit mild symptoms, officials are closely monitoring the situation to prevent any clustering of infections.</p>

<h2><strong>Genomic sequencing directive</strong></h2>

<p>In response to a sudden increase in Covid&nbsp;cases across various states, the central government has instructed states to send samples of all positive test swabs for whole genome sequencing. This initiative aims to identify the specific set of mutations associated with the JN.1 subvariant.</p>

<p>As of the latest update, India recorded 640 new Covid-19 cases in the past 24 hours, bringing the active tally to 2,997. The total death toll stands at 5,33,328, with one new death reported in Kerala. The country's overall Covid-19 case tally has reached&nbsp;45000000.</p>

<p><a href="https://www.wionews.com/india-news/kerala-more-than-200-fresh-covid-cases-a-death-recorded-in-last-24-hours-672621">Also read |&nbsp;India: More than 200 fresh Covid cases, one death recorded in last 24 hours in Kerala</a></p>

<h2><strong>Affected states and individual surveillance guidelines</strong></h2>

<p>States experiencing a notable increase in Covid-19 cases include Kerala, Karnataka, Tamil Nadu, Maharashtra, Goa, Puducherry, Gujarat, Telangana, Punjab, and Delhi. In response, several states are formulating individual surveillance guidelines.</p>

<p><strong>State-level responses</strong></p>

<ul>
	<li><strong>Kerala:</strong> Health minister Veena George assures that the situation is under control, emphasizing the high testing rates in the state. Genomic sequencing has been underway since November.</li>
	<li><strong>Karnataka:</strong> Health minister Dinesh Gundu Rao urges caution but reassures the public that no immediate restrictions will be imposed.</li>
	<li><strong>Rajasthan:</strong> Officials establish a state-level team for the prevention and control of Covid-19 infections in light of the rising cases.</li>
	<li><strong>Bihar:</strong> Chief minister Nitish Kumar chairs a meeting, directing officials to enhance testing rates and ensure the availability of essential resources in hospitals. He stressed on awareness campaigns about Covid-appropriate behaviour.</li>
</ul>

<p><strong>Also watch |&nbsp;COVID-19 India: WHO says, 'JN.1 poses low risk at present' | The India Story</strong></p>

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<p>Government data indicates that 93 per cent of those infected with the JN.1 subvariant exhibit mild symptoms and are isolating at home. Former WHO chief scientist Dr&nbsp;Soumya Swaminathan has urged people not to panic and has&nbsp;characterised&nbsp;the variant as a "variant of interest" rather than a "variant of concern." Only a small percentage of infected individuals require ventilator support, ICU admission, or oxygen support.</p>

<p><em>(With inputs from agencies)</em></p>


India has reported a total of 22 cases of the COVID-19 subvariant JN.1, prompting health authorities to implement precautionary measures to curb further spread. While all reported cases exhibit mild symptoms, officials are closely monitoring the situation to prevent any clustering of infections.

India has reported a total of 22 cases of the COVID-19 subvariant JN.1, prompting health authorities to implement precautionary measures to curb further spread. While all reported cases exhibit mild symptoms, officials are closely monitoring the situation to prevent any clustering of infections. Genomic sequencing directive In response to a sudden increase in Covid cases across various states, the central government has instructed states to send samples of all positive test swabs for whole genome sequencing. This initiative aims to identify the specific set of mutations associated with the JN.1 subvariant. As of the latest update, India recorded 640 new Covid-19 cases in the past 24 hours, bringing the active tally to 2,997. The total death toll stands at 5,33,328, with one new death reported in Kerala. The country's overall Covid-19 case tally has reached 45000000. Also read | India: More than 200 fresh Covid cases, one death recorded in last 24 hours in Kerala Affected states and individual surveillance guidelines States experiencing a notable increase in Covid-19 cases include Kerala, Karnataka, Tamil Nadu, Maharashtra, Goa, Puducherry, Gujarat, Telangana, Punjab, and Delhi. In response, several states are formulating individual surveillance guidelines. State-level responses Kerala: Health minister Veena George assures that the situation is under control, emphasizing the high testing rates in the state. Genomic sequencing has been underway since November. Karnataka: Health minister Dinesh Gundu Rao urges caution but reassures the public that no immediate restrictions will be imposed. Rajasthan: Officials establish a state-level team for the prevention and control of Covid-19 infections in light of the rising cases. Bihar: Chief minister Nitish Kumar chairs a meeting, directing officials to enhance testing rates and ensure the availability of essential resources in hospitals. He stressed on awareness campaigns about Covid-appropriate behaviour. Also watch | COVID-19 India: WHO says, 'JN.1 poses low risk at present' | The India Story Government data indicates that 93 per cent of those infected with the JN.1 subvariant exhibit mild symptoms and are isolating at home. Former WHO chief scientist Dr Soumya Swaminathan has urged people not to panic and has characterised the variant as a "variant of interest" rather than a "variant of concern." Only a small percentage of infected individuals require ventilator support, ICU admission, or oxygen support. (With inputs from agencies)

Covid JN.1 scare: India registers 22 subvariant cases; Centre orders genome sequencing

<p>An expert has predicted that within five years, rare diseases in children would be much easier to spot.&nbsp;Professor Matt Brown, the Chief Scientific Officer at Genomics England has predicted that very soon parents will be able to have it checked if their baby is at a higher risk of illnesses. He said that for this, parents could have their children’s genetic code read by the NHS.</p>

<p><strong>Also read |&nbsp;<a href="https://www.wionews.com/science/this-is-how-you-can-beat-health-hazards-of-sitting-all-day-552608">Dread health hazards of sitting all day, take a five-minute walk every half an hour</a></strong></p>

<p>Currently, each year, about 3,000 children in Britain are born with rare conditions and on average it takes up to five years, countless tests and visits to doctors for them to get a diagnosis. The delays can cause irreparable damage, which, thanks to this genome, sequencing could be avoided.</p>

<p>Last month, Genomic England and NHS announced the ‘Newborn Genomes Programme’. The pilot scheme which was announced last month will sequence the genomes of 100,000 babies over the next two years.&nbsp;</p>

<p><strong>Also read |&nbsp;<a href="https://www.wionews.com/science/hormone-replacement-therapy-may-help-reduce-risk-of-alzheimers-disease-in-women-study-552570">Hormone replacement therapy may help reduce risk of Alzheimer’s disease in women: Study</a></strong></p>

<p>As per the vision document, if the £105 million ($128.2 million) pilot is successful, it will be added to the NHS routine care. However, Brown remarked that the programme would never be compulsory and people will have to consent to have their baby’s genome sequenced by NHS.</p>

<p>Currently, whole genome sequencing (WGS) as per Daily Mail costs the NHS £800 ($978) to £1,000 ($1,223) every time, however with the programme it would cost around £150 ($183).</p>

<p><em>(With inputs from agencies)</em></p>

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An expert has predicted that within five years, rare diseases in children would be much easier to spot. Professor Matt Brown, the Chief Scientific Officer at Genomics England has predicted that very soon parents will be able to have it checked if their baby is at a higher risk of illnesses.

An expert has predicted that within five years, rare diseases in children would be much easier to spot. Professor Matt Brown, the Chief Scientific Officer at Genomics England has predicted that very soon parents will be able to have it checked if their baby is at a higher risk of illnesses. He said that for this, parents could have their children’s genetic code read by the NHS. Also read | Dread health hazards of sitting all day, take a five-minute walk every half an hour Currently, each year, about 3,000 children in Britain are born with rare conditions and on average it takes up to five years, countless tests and visits to doctors for them to get a diagnosis. The delays can cause irreparable damage, which, thanks to this genome, sequencing could be avoided. Last month, Genomic England and NHS announced the ‘Newborn Genomes Programme’. The pilot scheme which was announced last month will sequence the genomes of 100,000 babies over the next two years. Also read | Hormone replacement therapy may help reduce risk of Alzheimer’s disease in women: Study As per the vision document, if the £105 million ($128.2 million) pilot is successful, it will be added to the NHS routine care. However, Brown remarked that the programme would never be compulsory and people will have to consent to have their baby’s genome sequenced by NHS. Currently, whole genome sequencing (WGS) as per Daily Mail costs the NHS £800 ($978) to £1,000 ($1,223) every time, however with the programme it would cost around £150 ($183). (With inputs from agencies) WATCH WION LIVE HERE You can now write for wionews.com and be a part of the community. Share your stories and opinions with us here.

UK's NHS and Genomics England to use genome sequencing to identify rare diseases in babies

<p>A senior medical officer of Gaya, Bihar&nbsp;confirmed on Monday that samples of four foreigners who tested positive for Covid-19 at the Buddhist pilgrimage site of Gaya were sent for genome sequencing on Sunday. As stated by the official, a second person, a 60-year-old British woman, also tested positive last week before the central government formally requested that states amplify their analysis of positive Covid-19 cases in order to find new coronavirus variants amid a wave that was spiralling out of control in China. As per Gaya civil surgeon Dr Ranjan Kumar Singh, she has returned to her native country.</p>

<p>Four foreigners tested positive on Sunday, three of them from Thailand and one from Myanmar.</p>

<p>The five were asymptomatic when they undertook random testing at the Gaya international airport last week, according to Dr Singh.</p>

<p>“We have isolated two foreigners (from Thailand) at their hotel rooms at Bodh Gaya,” the medical officer said. The administration has not been able to track down the third person from Thailand since the person’s mobile phone number was switched off.</p>

<p>Prior to receiving the test results, the resident of Myanmar departed Gaya for Srinagar through Delhi. As soon as the results of the confirmatory test were received, according to Dr Singh, the airport personnel was made aware of his Covid-19 status.</p>

<p>Following a positive test from a Thai national on December 23, the district administration said that tests were also conducted on around 27 additional travellers in the same travel group. As a result of the contact tracing inquiry, two additional people had positive tests.</p>

<p>Prior to the Dalai Lama's discourse&nbsp;which is expected to draw approximately 100,000 followers and is set to take place from December 29 to 31, incidences of Covid-19 have been discovered. Around 20,000 worshippers from 50 nations have registered online for the event, according to those with knowledge of the situation.</p>

<p>The Gaya district magistrate Thiyagarajan SM has advised people to wear masks and follow&nbsp;Covid protocols, particularly by keeping a distance from others. Additionally, he has requested that only those who test negative be permitted to meet the Dalai Lama.</p>

<p><em>(With inputs from agencies)</em></p>

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A senior medical officer of Gaya, Bihar confirmed on Monday that samples of four foreigners who tested positive for Covid-19 at the Buddhist pilgrimage site of Gaya were sent for genome sequencing on Sunday.

A senior medical officer of Gaya, Bihar confirmed on Monday that samples of four foreigners who tested positive for Covid-19 at the Buddhist pilgrimage site of Gaya were sent for genome sequencing on Sunday. As stated by the official, a second person, a 60-year-old British woman, also tested positive last week before the central government formally requested that states amplify their analysis of positive Covid-19 cases in order to find new coronavirus variants amid a wave that was spiralling out of control in China. As per Gaya civil surgeon Dr Ranjan Kumar Singh, she has returned to her native country. Four foreigners tested positive on Sunday, three of them from Thailand and one from Myanmar. The five were asymptomatic when they undertook random testing at the Gaya international airport last week, according to Dr Singh. “We have isolated two foreigners (from Thailand) at their hotel rooms at Bodh Gaya,” the medical officer said. The administration has not been able to track down the third person from Thailand since the person’s mobile phone number was switched off. Prior to receiving the test results, the resident of Myanmar departed Gaya for Srinagar through Delhi. As soon as the results of the confirmatory test were received, according to Dr Singh, the airport personnel was made aware of his Covid-19 status. Following a positive test from a Thai national on December 23, the district administration said that tests were also conducted on around 27 additional travellers in the same travel group. As a result of the contact tracing inquiry, two additional people had positive tests. Prior to the Dalai Lama's discourse which is expected to draw approximately 100,000 followers and is set to take place from December 29 to 31, incidences of Covid-19 have been discovered. Around 20,000 worshippers from 50 nations have registered online for the event, according to those with knowledge of the situation. The Gaya district magistrate Thiyagarajan SM has advised people to wear masks and follow Covid protocols, particularly by keeping a distance from others. Additionally, he has requested that only those who test negative be permitted to meet the Dalai Lama. (With inputs from agencies) WATCH WION LIVE HERE:

Bihar: Five foreigners test positive for COVID-19 at Gaya, four samples sent for genome sequencing

With the number of the Covid cases soaring in various nations, India stepped up for genome sequencing of Covid positive cases. States have been requested to ensure that samples are sent to the labs on daily basis. Watch to know further.

India is focusing on genome sequencing as the latest move amid Covid surge in other countries

With the number of the Covid cases soaring in various nations, India stepped up for genome sequencing of Covid positive cases. States have been requested to ensure that samples are sent to the labs on daily basis.

Indian states asked to submit samples for Genome sequencing

genome-sequencing

Genome Sequencing, News on Genome Sequencing, stories on Genome Sequencing, articles on Genome Sequencing, Genome Sequencing stories at Wion, Genome Sequencing news, Genome Sequencing latest news