A promising new drug is raising hopes for bladder cancer patients by potentially reducing the need for life-changing surgery. Researchers say the treatment could mark a significant step forward in cancer care, offering patients an alternative approach while improving quality of life.

Could this breakthrough transform the future of bladder cancer treatment? Here's what the latest findings reveal.

:ngame-changer for Bladder Cancer Patients?

The majority of lung cancer cases in India are linked to non-smokers, a startling&nbsp;study has&nbsp;revealed. Factors such as genetic&nbsp;susceptibility, hormonal status and rise in poor air quality have&nbsp;been highlighted as the main cause of lung cancer in Indians.

The research was conducted at Mumbai-based Tata Memorial Centre and titled&nbsp;‘Uniqueness of lung cancer in Southeast Asia’. It has been published in medical journal&nbsp;The Lancet and the&nbsp;findings emphasised that lung cancer in Southeast Asia, particularly in India, stands apart from cases in other regions of the world.&nbsp;

"Lung cancer in Southeast Asia is similar but also very different in myriad aspects from that in the West, as well as other parts of Asia," the study stated.&nbsp;

Researchers noted that despite being non-smokers, lung cancer manifests among Indians, ten years earlier as compared to Western countries.&nbsp;

“Lung cancer presents approximately a decade earlier in India as compared to Western countries, with a mean age at diagnosis of 54–70 years,” read the report.

WATCH |&nbsp;Gravitas | 'Forever chemicals' found in contact lenses: Study

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<h2>India and pollution&nbsp;</h2>

According to data, India accounted for&nbsp;72,510 lung cancer cases and 66,279 deaths in 2020. On the whole, lung cancer accounted for the third most commonly diagnosed cancer in Southeast Asia with 1.85 million new&nbsp;cases reported.&nbsp;&nbsp;&nbsp;

The study quoted a World Air Quality Report in 2022 and stated that South Asia is home to 37 of the 40 polluted cities across the world. India and its numerous tier-1, tier-and 2 cities, including the capital New Delhi, remain polluted nearly throughout the year - further increasing the risk of cancer among non-smokers.&nbsp;

Exposure to particulate matter PM2.5,&nbsp;asbestos, chromium, cadmium, arsenic and coal as well as passive smoking are the contributing factors.

The study highlighted that only 31.7 per cent of patients in India with Stages I to IIIB lung cancer, underwent curative intent therapy while only 13.4 per cent underwent curative resection.&nbsp;&nbsp;

The research concluded that a "fair amount of work" had&nbsp;been done, "but there is a lot more that can and should be done to ensure that all patients with lung cancer receive the same level of high-quality care, regardless of their geographical location or ethnicity".

(With inputs from agencies)

The majority of lung cancer cases in India are linked to non-smokers, a startling study has revealed. Factors such as genetic susceptibility, hormonal status and rise in poor air quality have been highlighted as the main cause of lung cancer in Indians.

The majority of lung cancer cases in India are linked to non-smokers, a startling study has revealed. Factors such as genetic susceptibility, hormonal status and rise in poor air quality have been highlighted as the main cause of lung cancer in Indians. The research was conducted at Mumbai-based Tata Memorial Centre and titled ‘Uniqueness of lung cancer in Southeast Asia’. It has been published in medical journal The Lancet and the findings emphasised that lung cancer in Southeast Asia, particularly in India, stands apart from cases in other regions of the world. "Lung cancer in Southeast Asia is similar but also very different in myriad aspects from that in the West, as well as other parts of Asia," the study stated. Researchers noted that despite being non-smokers, lung cancer manifests among Indians, ten years earlier as compared to Western countries. “Lung cancer presents approximately a decade earlier in India as compared to Western countries, with a mean age at diagnosis of 54–70 years,” read the report. WATCH | Gravitas | 'Forever chemicals' found in contact lenses: Study Also read | What happens to narcissist people as they grow older? Science has the answer India and pollution According to data, India accounted for 72,510 lung cancer cases and 66,279 deaths in 2020. On the whole, lung cancer accounted for the third most commonly diagnosed cancer in Southeast Asia with 1.85 million new cases reported. The study quoted a World Air Quality Report in 2022 and stated that South Asia is home to 37 of the 40 polluted cities across the world. India and its numerous tier-1, tier-and 2 cities, including the capital New Delhi, remain polluted nearly throughout the year - further increasing the risk of cancer among non-smokers. Exposure to particulate matter PM2.5, asbestos, chromium, cadmium, arsenic and coal as well as passive smoking are the contributing factors. The study highlighted that only 31.7 per cent of patients in India with Stages I to IIIB lung cancer, underwent curative intent therapy while only 13.4 per cent underwent curative resection. The research concluded that a "fair amount of work" had been done, "but there is a lot more that can and should be done to ensure that all patients with lung cancer receive the same level of high-quality care, regardless of their geographical location or ethnicity". (With inputs from agencies)

Majority of lung cancer patients in India are non-smokers, startling study reveals

The World Health Organization's cancer agency recently warned that the number of new cancer cases will rise to more than 35 million in 2050, which is 77 per cent higher than the figure in 2022. Tobacco, alcohol, obesity and air pollution are key factors in the estimated rise of cancer cases, the WHO's International Agency for Research on Cancer (IARC) said. In 2022, some 20 million cases were diagnosed. A statement released by WHO read, "Over 35 million new cancer cases are predicted in 2050."&nbsp;

"The rapidly-growing global cancer burden reflects both population ageing and growth, as well as changes to people's exposure to risk factors, several of which are associated with socioeconomic development," it said.&nbsp;

February 4 is marked as World Cancer Day. WHO said that between 2022 and 2024, the focus of this day is to help "Close the cancer gap" and this year marks the third and final year of the campaign.&nbsp;

Also read:&nbsp;<a href="https://www.wionews.com/health-and-wellness/cervical-cancer-experts-tell-importance-of-symptoms-and-preventive-measures-a-must-read-for-all-women-683639">Cervical Cancer: Experts talk about preventive measures. A must-read for all women</a>&nbsp;

The theme for this year is, "Together, we challenge those in power" and this theme reflects the global call for leaders to prioritise and invest in cancer prevention and care, as well as do more to achieve a just and cancer-free world.&nbsp;

Cancer is not just about its diagnosis and its treatment, it goes far beyond. This deadly disease drains the patient physically, mentally and financially. Also, it comes as a massive responsibility for the family attending a patient.&nbsp;

<h2>Redefining support for breast cancer patients in India&nbsp;</h2>

WION explored how to redefine support for breast cancer patients in India and understand the concept beyond diagnosis. To learn more about this, WION got in touch with Dr Kanchan Kaur, who is the Senior Director, Breast Cancer, Cancer Care, Medanta, Gurugram, who&nbsp;said, "Breast cancer is the most common cancer in women globally, overtaking lung cancer in 2020 with around 2.3 million new cases, making up 11.7% of all cancer cases."&nbsp;

"Studies predict that global breast cancer cases will reach nearly 2 million by 2030. In India, the incidence of breast cancer in females has increased by 39.1% over the last 26 years. According to 2020 data, breast cancer accounted for 13.5% (178,361) of all cancer cases and 10.6% (90,408) of all deaths in India," Dr Kaur added.&nbsp;

Dr Kaur weighed in on the holistic approach to breast cancer care. She said that the treatment for breast cancer involves using medical measures to cure or alleviate a condition.&nbsp;

"Survivorship, which runs alongside treatment, aims for an improved quality of life. In the context of cancer care, survivorship covers the health and life of a person with cancer from diagnosis to end of life. It includes the lasting physical, social, mental, and financial effects of cancer beyond diagnosis and treatment completion. It also deals with issues like post-treatment follow-up, potential recurrences, second cancers, and overall quality of life," she said.&nbsp;

In recent years, there has been a growing awareness of the need for a holistic approach to breast cancer care, extending beyond medical interventions. Organisations and healthcare providers in India are increasingly focussing on providing comprehensive support services that address the multifaceted needs of individuals grappling with breast cancer, Dr Kaur said.&nbsp;

Support groups and counselling&nbsp;

One key aspect of holistic support is the establishment of breast cancer support groups. These groups offer a platform for patients to share their experiences, fears, and triumphs with others who understand the unique challenges of their journey. Counselling services, both individual and in group sessions, provide emotional support, helping patients cope with the psychological impact of breast cancer diagnosis.&nbsp;

Awareness and education&nbsp;

Raising awareness and educating the public about breast cancer are crucial components of a comprehensive support system. Many breast cancer patients in India still face delays in seeking medical help due to a lack of awareness or misconceptions. Educational initiatives aimed at dispelling myths, emphasising the importance of early detection, and promoting regular screenings are essential in empowering both patients and their families.&nbsp;

Financial support&nbsp;

The financial burden associated with breast cancer treatment can be overwhelming for many patients and their families. Recognising this challenge, support programmes&nbsp;offering financial assistance have become integral to holistic breast cancer care in India. These programmes&nbsp;may cover treatment costs, and medications, and even provide aid for daily living expenses.&nbsp;

Also read:&nbsp;<a href="https://www.wionews.com/health-and-wellness/nutrition-of-premature-babies-experts-share-a-must-follow-guide-for-mothers-and-caregivers-659776">Nutrition of premature babies: Experts share a must-follow guide for mothers and caregivers</a>&nbsp;

<h2>Importance of palliative care&nbsp;</h2>

Dr Jyoti Wadhwa, who is the Vice-Chairperson and HOD, Medical Oncology and Hematology, Paras Health, Gurugram, told WION about palliative care, which is an interdisciplinary medical caregiving approach focussed at improving the quality of life and mitigating suffering among people with serious, complex, and often terminal illnesses.&nbsp;

As per the National Cancer Registry Programme, it is projected that approximately 1 in 9 individuals in India may experience cancer during their lifetime. Additionally, there are nearly 1.5 million new cancer cases reported annually in the country, leading to the loss of lives for around 800,000 Indians each year.&nbsp;

Dr Wadhwa said, "Encouragingly, progress in oncology research and development over the past few decades has resulted in advancements in cancer treatment, contributing to an improved survival rate for individuals grappling with this disease." She added that the role of palliative care is to improve&nbsp;the quality of life of cancer patients.&nbsp;

What is palliative care? Palliative care is a comprehensive approach to improving the quality of life for patients as well as their families when they are coping with the difficulties that come with life-threatening illnesses such as cancer.&nbsp;

This specialised care focuses on several areas, including symptom relief, pain management, nutritional therapy, physical therapy, home care before and after treatment, spiritual counselling, introduction to relaxation techniques, and end-of-life preferences, ensuring that the patient's values and wishes are respected.&nbsp;

Cancer survivors often face significant life changes that can be overwhelming, and palliative care is specifically designed to enhance their quality of life.&nbsp;

Dr Wadhwa said, "Providing emotional and psychological support is critically essential for the holistic well-being of individuals facing cancer. Fear, anxiety, and depression are just a few of the strong feelings that cancer patients commonly experience. It is the responsibility of healthcare providers to mitigate these negative emotions and promote resilience, security, and comfort."&nbsp;

Disclaimer: This&nbsp;content provided on the website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment.&nbsp;

The World Health Organization's cancer agency recently warned that the number of new cancer cases will rise to more than 35 million in 2050, which is 77 per cent higher than the figure in 2022.

The World Health Organization's cancer agency recently warned that the number of new cancer cases will rise to more than 35 million in 2050, which is 77 per cent higher than the figure in 2022. Tobacco, alcohol, obesity and air pollution are key factors in the estimated rise of cancer cases, the WHO's International Agency for Research on Cancer (IARC) said. In 2022, some 20 million cases were diagnosed. A statement released by WHO read, "Over 35 million new cancer cases are predicted in 2050." "The rapidly-growing global cancer burden reflects both population ageing and growth, as well as changes to people's exposure to risk factors, several of which are associated with socioeconomic development," it said. February 4 is marked as World Cancer Day. WHO said that between 2022 and 2024, the focus of this day is to help "Close the cancer gap" and this year marks the third and final year of the campaign. Also read: Cervical Cancer: Experts talk about preventive measures. A must-read for all women The theme for this year is, "Together, we challenge those in power" and this theme reflects the global call for leaders to prioritise and invest in cancer prevention and care, as well as do more to achieve a just and cancer-free world. Cancer is not just about its diagnosis and its treatment, it goes far beyond. This deadly disease drains the patient physically, mentally and financially. Also, it comes as a massive responsibility for the family attending a patient. Redefining support for breast cancer patients in India WION explored how to redefine support for breast cancer patients in India and understand the concept beyond diagnosis. To learn more about this, WION got in touch with Dr Kanchan Kaur, who is the Senior Director, Breast Cancer, Cancer Care, Medanta, Gurugram, who said, "Breast cancer is the most common cancer in women globally, overtaking lung cancer in 2020 with around 2.3 million new cases, making up 11.7% of all cancer cases." "Studies predict that global breast cancer cases will reach nearly 2 million by 2030. In India, the incidence of breast cancer in females has increased by 39.1% over the last 26 years. According to 2020 data, breast cancer accounted for 13.5% (178,361) of all cancer cases and 10.6% (90,408) of all deaths in India," Dr Kaur added. Dr Kaur weighed in on the holistic approach to breast cancer care. She said that the treatment for breast cancer involves using medical measures to cure or alleviate a condition. "Survivorship, which runs alongside treatment, aims for an improved quality of life. In the context of cancer care, survivorship covers the health and life of a person with cancer from diagnosis to end of life. It includes the lasting physical, social, mental, and financial effects of cancer beyond diagnosis and treatment completion. It also deals with issues like post-treatment follow-up, potential recurrences, second cancers, and overall quality of life," she said. In recent years, there has been a growing awareness of the need for a holistic approach to breast cancer care, extending beyond medical interventions. Organisations and healthcare providers in India are increasingly focussing on providing comprehensive support services that address the multifaceted needs of individuals grappling with breast cancer, Dr Kaur said. Support groups and counselling One key aspect of holistic support is the establishment of breast cancer support groups. These groups offer a platform for patients to share their experiences, fears, and triumphs with others who understand the unique challenges of their journey. Counselling services, both individual and in group sessions, provide emotional support, helping patients cope with the psychological impact of breast cancer diagnosis. Awareness and education Raising awareness and educating the public about breast cancer are crucial components of a comprehensive support system. Many breast cancer patients in India still face delays in seeking medical help due to a lack of awareness or misconceptions. Educational initiatives aimed at dispelling myths, emphasising the importance of early detection, and promoting regular screenings are essential in empowering both patients and their families. Financial support The financial burden associated with breast cancer treatment can be overwhelming for many patients and their families. Recognising this challenge, support programmes offering financial assistance have become integral to holistic breast cancer care in India. These programmes may cover treatment costs, and medications, and even provide aid for daily living expenses. Also read: Nutrition of premature babies: Experts share a must-follow guide for mothers and caregivers Importance of palliative care Dr Jyoti Wadhwa, who is the Vice-Chairperson and HOD, Medical Oncology and Hematology, Paras Health, Gurugram, told WION about palliative care, which is an interdisciplinary medical caregiving approach focussed at improving the quality of life and mitigating suffering among people with serious, complex, and often terminal illnesses. As per the National Cancer Registry Programme, it is projected that approximately 1 in 9 individuals in India may experience cancer during their lifetime. Additionally, there are nearly 1.5 million new cancer cases reported annually in the country, leading to the loss of lives for around 800,000 Indians each year. Dr Wadhwa said, "Encouragingly, progress in oncology research and development over the past few decades has resulted in advancements in cancer treatment, contributing to an improved survival rate for individuals grappling with this disease." She added that the role of palliative care is to improve the quality of life of cancer patients. What is palliative care? Palliative care is a comprehensive approach to improving the quality of life for patients as well as their families when they are coping with the difficulties that come with life-threatening illnesses such as cancer. This specialised care focuses on several areas, including symptom relief, pain management, nutritional therapy, physical therapy, home care before and after treatment, spiritual counselling, introduction to relaxation techniques, and end-of-life preferences, ensuring that the patient's values and wishes are respected. Cancer survivors often face significant life changes that can be overwhelming, and palliative care is specifically designed to enhance their quality of life. Dr Wadhwa said, "Providing emotional and psychological support is critically essential for the holistic well-being of individuals facing cancer. Fear, anxiety, and depression are just a few of the strong feelings that cancer patients commonly experience. It is the responsibility of healthcare providers to mitigate these negative emotions and promote resilience, security, and comfort." Disclaimer: This content provided on the website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment.

World Cancer Day: Redefining support for breast cancer patients in India, importance of palliative care

Receiving a cancer diagnosis is a life-altering moment not just for the&nbsp;patients but also for their family members. In the realm of comprehensive and&nbsp;holistic care, emotional well-being is a vital and integral component. It is often a&nbsp;wandering question in the minds of most healthcare providers and family&nbsp; 
members, “How can we emotionally support individuals suffering from cancer?”&nbsp;

It is not one single act that can make a big difference, rather it is a combination&nbsp;of multiple meaningful actions that can bring ripples of change. Acknowledging the emotional toll on individuals with cancer defines&nbsp;the foundation for effective support and a sense of understanding. Encouraging&nbsp;open dialogue without judgment allows patients to express their fears,&nbsp;concerns, and hopes. Sitting with loved ones through their challenging times with a compassionate presence and empathy can serve as a powerful source of&nbsp;support. Through active listening, it is essential to address the uncertainty with&nbsp;respect to the different stages of treatment and recovery and validate the wide&nbsp;range of emotions felt through the journey.

Each person’s journey through cancer is unique. The emotional support&nbsp;should be tailored through understanding their personal preferences. Some&nbsp;may find support just through quiet companionship, while others may wish to&nbsp;receive space for vocal expressions. Understanding these aspects can enhance&nbsp;the effectiveness of the support provided. Alongside the unique preferences, it&nbsp;is important to keep reminding the family members and their dear ones battling&nbsp;with illness to acknowledge the milestones and build a sense of gratitude and&nbsp;love towards themselves.

Your loved ones should be encouraged to foster a mindful presence of their&nbsp;being. They tend to ruminate in the past in search of the reasons for developing&nbsp;cancer in their body or anticipating the possible side effects of the treatment&nbsp;and their prognosis. With that hustle, they forget to recognise the importance&nbsp;of efforts they can make in the present moment to build a better mind-body&nbsp;connection.

Also read:&nbsp;<a href="https://www.wionews.com/entertainment/lifestyle/news-understanding-the-impact-of-thyroid-disorders-on-the-musculoskeletal-system-681999">Understanding the impact of Thyroid disorders on the musculoskeletal system</a>

Embracing mindfulness and self-care through simple acts of mindful eating, regular exercise, sufficient quality sleep and building a better lifestyle&nbsp;can make a difference. Not to forget, helping individuals find pockets of joyful&nbsp;moments, realising they are important and people care for them can further&nbsp;provide enhanced emotional well-being.

In addition to motivating your close ones to build better emotional&nbsp;regulation through the illness, providing a consistent supportive connection from your side as a healthcare provider and caregiver can immensely impact&nbsp;their well-being. It is needed to understand that the cancer journey can be&nbsp;marked by fluctuations in emotions, from moments of optimism to times of&nbsp;deep despair. Regular check-ins can convey a commitment to stand with them&nbsp;through the phases of treatment and also aid them in developing a sense of trust&nbsp;and security.

Individuals who feel emotionally well-supported tend to express&nbsp;themselves better, build resilience, openly ask questions and actively participate&nbsp;in the shared decision-making process related to their treatment. Emotional&nbsp;support is an ongoing process. It helps to build a strong foundation of physical&nbsp;and mental well-being, and healthy coping through the complex journey of&nbsp;treatment and survivorship. Providing support&nbsp;and nurturing emotional well-being is one of the greatest forms of investment needed by individuals dealing&nbsp; 
with cancer for their overall health and a better quality of life

(With inputs from&nbsp;Dr Aarushi Saluja, Psycho-Oncologist, Department of Mental Health and Behavioral Sciences, Fortis Memorial Research Institute, Gurugram)

Disclaimer: Please note that the information provided on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare providers with any questions you may have regarding a medical condition. The content provided on this website should not be used to diagnose or treat any health problem or disease. If you have or suspect that you have a medical problem, please contact your healthcare provider immediately. Never disregard professional medical advice or delay in seeking it because of something you have read on a website.

Receiving a cancer diagnosis is a life-altering moment not just for the patients but also for their family members. In the realm of comprehensive and holistic care, emotional well-being is a vital and integral component.

Receiving a cancer diagnosis is a life-altering moment not just for the patients but also for their family members. In the realm of comprehensive and holistic care, emotional well-being is a vital and integral component. It is often a wandering question in the minds of most healthcare providers and family members, “How can we emotionally support individuals suffering from cancer?” It is not one single act that can make a big difference, rather it is a combination of multiple meaningful actions that can bring ripples of change. Acknowledging the emotional toll on individuals with cancer defines the foundation for effective support and a sense of understanding. Encouraging open dialogue without judgment allows patients to express their fears, concerns, and hopes. Sitting with loved ones through their challenging times with a compassionate presence and empathy can serve as a powerful source of support. Through active listening, it is essential to address the uncertainty with respect to the different stages of treatment and recovery and validate the wide range of emotions felt through the journey. Each person’s journey through cancer is unique. The emotional support should be tailored through understanding their personal preferences. Some may find support just through quiet companionship, while others may wish to receive space for vocal expressions. Understanding these aspects can enhance the effectiveness of the support provided. Alongside the unique preferences, it is important to keep reminding the family members and their dear ones battling with illness to acknowledge the milestones and build a sense of gratitude and love towards themselves. Your loved ones should be encouraged to foster a mindful presence of their being. They tend to ruminate in the past in search of the reasons for developing cancer in their body or anticipating the possible side effects of the treatment and their prognosis. With that hustle, they forget to recognise the importance of efforts they can make in the present moment to build a better mind-body connection. Also read: Understanding the impact of Thyroid disorders on the musculoskeletal system Embracing mindfulness and self-care through simple acts of mindful eating, regular exercise, sufficient quality sleep and building a better lifestyle can make a difference. Not to forget, helping individuals find pockets of joyful moments, realising they are important and people care for them can further provide enhanced emotional well-being. In addition to motivating your close ones to build better emotional regulation through the illness, providing a consistent supportive connection from your side as a healthcare provider and caregiver can immensely impact their well-being. It is needed to understand that the cancer journey can be marked by fluctuations in emotions, from moments of optimism to times of deep despair. Regular check-ins can convey a commitment to stand with them through the phases of treatment and also aid them in developing a sense of trust and security. Individuals who feel emotionally well-supported tend to express themselves better, build resilience, openly ask questions and actively participate in the shared decision-making process related to their treatment. Emotional support is an ongoing process. It helps to build a strong foundation of physical and mental well-being, and healthy coping through the complex journey of treatment and survivorship. Providing support and nurturing emotional well-being is one of the greatest forms of investment needed by individuals dealing with cancer for their overall health and a better quality of life (With inputs from Dr Aarushi Saluja, Psycho-Oncologist, Department of Mental Health and Behavioral Sciences, Fortis Memorial Research Institute, Gurugram) Disclaimer: Please note that the information provided on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare providers with any questions you may have regarding a medical condition. The content provided on this website should not be used to diagnose or treat any health problem or disease. If you have or suspect that you have a medical problem, please contact your healthcare provider immediately. Never disregard professional medical advice or delay in seeking it because of something you have read on a website.

How can we emotionally support someone suffering from cancer?

A US court ruled that Johnson & Johnson cannot use the bankruptcy of one of its subsidiaries as leverage to force thousands of cancer patients to withdraw their cases and accept a settlement offer. The appeals court made it clear that a company must be in "immediate, imminent, and clear" financial trouble before it can file for bankruptcy.

Johnson & Johnson's $8.9 bn settlement plan in jeopardy | World DNA

Mumbai-based Epigeneres Biotech Private Ltd, in collaboration with Singapore-based Tzar Labs, claims to have developed the world’s first pan-cancer imminent-detection blood test. According to Tzar Labs' Ashish Tripathi, the test can detect mutations and dysfunction pathways from a blood sample much before a tumor forms, enabling early detection and significantly improving survival rates. The technology has undergone a 1,000-patient study in India and clinical trials with the NHS have commenced. The test has already been launched in India, with further expansion plans underway. What are the key claims made by Tzar Labs regarding their blood test for cancer detection and how does early detection impact the prognosis and treatment of cancer patients? Watch Vikram Chandra in a special conversation with Ashish Tripathi

Hope on Horizon for cancer patients?

In a finding that can change the way how cancerous brain tumours are treated, a team of scientists led by an Indian, has found that cancerous cells link with healthy brain cells to become hyperactive. This in turn causes speedy cognitive loss and death in patients. The team of scientists from San Francisco Medical Centre&nbsp;was led by Saritha Krishna.&nbsp;

The team has also found out that a commonly used&nbsp;anti-seizure drug&nbsp;was effective in reducing hyperactivity of the tumour cells and even stopping their growth.

Press Trust of India reported that the study was published in latest issue of journal Nature.

These scientists have reportedly found out that the link up and communication between healthy brain cells and cancerous cells could be manipulated to slow down&nbsp;which can in turn, slow down or even halt growth of the tumour.&nbsp;

The study reportedly noted that these findings will be more beneficial for patients with glioblastoma. It is considered to be most fatal among adult brain cancers.

The study conducted by Krishna and fellow scientist Shawn Hervey-Jumper discovered a previously unknown mechanism by which brain tumours hijack and modify brain circuitry to cause a decline in cognitive activities in glioblastoma patients while recording the brain activity in patients undergoing awake-brain tumour surgery.

Krishna is a native of Thiruvananthapuram in southern Indian state of Kerala. She is the lead author of the paper. Krishna told PTI that when patients were given language tasks during awake brain surgery, in addition to the commonly known language areas of the brain, the scientists found activation in tumour-infiltrated brain regions. These regions were remote and farther away from language brain zones.

This unexpected finding showed that the deadly cancer cells can hijack and restructure connections in surrounding brain tissue to make them hyperactive, speeding up cognitive decline and shortening the survival period among patients.

Scientists were thus forced to carry out extensive biological characterisation of the connected tumour cells using brain organoids.&nbsp;

Brain organoids are small bundles of neurons derived from human stem cells and mouse models engrafted with human glioblastoma cells.

"These experiments revealed a key role of a protein called 'thrombospondin-1' in this neuronal hyperexcitability and that the drug, gabapentin, a commonly used anti-seizure medication, successfully reduced neuronal hyperexcitability and halted further tumour growth," the study quoted.

"Besides this known anti-seizure activity, this study discovering the anti-tumour effect of gabapentin using mouse models highlights the potential of repurposing this existing drug to target tumour growth, thereby expediting therapeutic drug development for patients with malignant glioma," Saritha said as quoted by the PTI.

"Non-invasive brain modulation techniques traditionally applied to modulate neuronal function in epilepsy and psychiatric diseases, could now be exploited in clinical trials and tested in patients with brain cancer to suppress glioma’s activity," she said.

(With inputs from agencies)

You can now write for wionews.com and be a part of the community. Share your stories and opinions with us <a href="https://www.wionews.com/content-contribution-registration-form">here</a>.

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In a finding that can change the way how cancerous brain tumours are treated, a team of scientists led by an Indian, has found that cancerous cells link with healthy brain cells to become hyperactive.

In a finding that can change the way how cancerous brain tumours are treated, a team of scientists led by an Indian, has found that cancerous cells link with healthy brain cells to become hyperactive. This in turn causes speedy cognitive loss and death in patients. The team of scientists from San Francisco Medical Centre was led by Saritha Krishna. The team has also found out that a commonly used anti-seizure drug was effective in reducing hyperactivity of the tumour cells and even stopping their growth. Press Trust of India reported that the study was published in latest issue of journal Nature. These scientists have reportedly found out that the link up and communication between healthy brain cells and cancerous cells could be manipulated to slow down which can in turn, slow down or even halt growth of the tumour. The study reportedly noted that these findings will be more beneficial for patients with glioblastoma. It is considered to be most fatal among adult brain cancers. The study conducted by Krishna and fellow scientist Shawn Hervey-Jumper discovered a previously unknown mechanism by which brain tumours hijack and modify brain circuitry to cause a decline in cognitive activities in glioblastoma patients while recording the brain activity in patients undergoing awake-brain tumour surgery. Krishna is a native of Thiruvananthapuram in southern Indian state of Kerala. She is the lead author of the paper. Krishna told PTI that when patients were given language tasks during awake brain surgery, in addition to the commonly known language areas of the brain, the scientists found activation in tumour-infiltrated brain regions. These regions were remote and farther away from language brain zones. This unexpected finding showed that the deadly cancer cells can hijack and restructure connections in surrounding brain tissue to make them hyperactive, speeding up cognitive decline and shortening the survival period among patients. Scientists were thus forced to carry out extensive biological characterisation of the connected tumour cells using brain organoids. Brain organoids are small bundles of neurons derived from human stem cells and mouse models engrafted with human glioblastoma cells. "These experiments revealed a key role of a protein called 'thrombospondin-1' in this neuronal hyperexcitability and that the drug, gabapentin, a commonly used anti-seizure medication, successfully reduced neuronal hyperexcitability and halted further tumour growth," the study quoted. "Besides this known anti-seizure activity, this study discovering the anti-tumour effect of gabapentin using mouse models highlights the potential of repurposing this existing drug to target tumour growth, thereby expediting therapeutic drug development for patients with malignant glioma," Saritha said as quoted by the PTI. "Non-invasive brain modulation techniques traditionally applied to modulate neuronal function in epilepsy and psychiatric diseases, could now be exploited in clinical trials and tested in patients with brain cancer to suppress glioma’s activity," she said. (With inputs from agencies) You can now write for wionews.com and be a part of the community. Share your stories and opinions with us here. WATCH WION LIVE HERE ×

US scientists, led by Indian, make big discovery that'll help brain cancer patients

There has been a crucial breakthrough in the fight against the cancer. It is a landmark event in medical history, a drug called Dostarlimab might be the cure for cancer that the world has been looking for for a long time.

18 rectal cancer patients cured in US Trial

Cancer patients who get COVID-19 are at high risk for poor outcomes and should be considered for priority access to coronavirus vaccines

Experts call for people with cancer to receive COVID vaccine first

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