A recent research by the Nuffield Trust health think tank reveals&nbsp;that medicine shortages have&nbsp;become "new normal" in the United Kingdom. The impact of these shortages has been amplified by the aftermath of Brexit, posing serious problems for medical personnel, pharmacists, the NHS, and patients across the country.

<h2>Shortage&nbsp;warnings issued by drug companies doubled</h2>

According to the report, there has been a significant rise in the number of warnings issued by drug companies regarding impending supply problems. These warnings have more than doubled, from 648 in 2020 to 1,634 the previous year.

“The rise in shortages of vital medicines from rare to commonplace has been a shocking development that few would have expected a decade ago,” said Mark Dayan, the report’s lead author, and the Nuffield Trust’s Brexit programme lead.

Medication shortages have mainly impacted ADHD, type 2 diabetes, and epilepsy. Despite guarantees, several medications, particularly those for ADHD, remain difficult to get even after the predicted deadlines for their reintroduction into normal circulation.

Patients with chronic illnesses are facing serious consequences due to these shortages. Nicola Swanborough from the Epilepsy Society told The Guardian, “Our helpline has been inundated with calls from desperate people who are having to travel miles, often visiting multiple pharmacies to try and access their medication.”

Also read:&nbsp;<a href="https://www.wionews.com/science/watching-sports-linked-to-better-physical-and-mental-well-being-study-713407">Watching sports linked to better physical and mental well-being: Study</a>

Paul Rees, the chief executive of the National Pharmacy Association said “Supply shortages are a real and present danger to those patients who rely on life-saving medicines for their wellbeing. Pharmacy teams have seen the problems get worse in this country over recent years, putting more patients at risk."&nbsp;

“Pharmacists … are spending hours a day hunting down stock, yet too often have to turn patients away. It’s distressing when pharmacy teams find themselves unable to provide prompt medicines services, through no fault of their own,” he added.

<h2>What are the reasons for&nbsp;medicine&nbsp;shortage in UK?</h2>

While global factors like the COVID-19 pandemic, inflation, and the war in Ukraine have contributed to the drug shortages, Brexit has significantly worsened the situation. The UK's departure from the EU has disrupted the smooth flow of medicines, leading to delays and uncertainties in drug supply chains.

“A clear picture emerged of underlying fragilities at a global and UK level, not fundamentally rooted in Brexit but exacerbated by it in some specific ways, especially through some companies removing the UK from their supply chains,” the study read.

The Royal Pharmaceutical Society recommended legislative reforms that would allow community pharmacists to issue alternate prescriptions when certain pharmaceuticals are unavailable.

The Department of Health and Social Care (DHSC) said that the majority of pharmaceuticals are still available and that concessionary pricing are not always connected to shortages.&nbsp; 
&nbsp;

A recent research by the Nuffield Trust health think tank reveals that medicine shortages have become "new normal" in the United Kingdom. The impact of these shortages has been amplified by the aftermath of Brexit, posing serious problems for medical personnel, pharmacists, the NHS, and patients across the country.

A recent research by the Nuffield Trust health think tank reveals that medicine shortages have become "new normal" in the United Kingdom. The impact of these shortages has been amplified by the aftermath of Brexit, posing serious problems for medical personnel, pharmacists, the NHS, and patients across the country. Shortage warnings issued by drug companies doubled According to the report, there has been a significant rise in the number of warnings issued by drug companies regarding impending supply problems. These warnings have more than doubled, from 648 in 2020 to 1,634 the previous year. “The rise in shortages of vital medicines from rare to commonplace has been a shocking development that few would have expected a decade ago,” said Mark Dayan, the report’s lead author, and the Nuffield Trust’s Brexit programme lead. Medication shortages have mainly impacted ADHD, type 2 diabetes, and epilepsy. Despite guarantees, several medications, particularly those for ADHD, remain difficult to get even after the predicted deadlines for their reintroduction into normal circulation. Patients with chronic illnesses are facing serious consequences due to these shortages. Nicola Swanborough from the Epilepsy Society told The Guardian, “Our helpline has been inundated with calls from desperate people who are having to travel miles, often visiting multiple pharmacies to try and access their medication.” Also read: Watching sports linked to better physical and mental well-being: Study Paul Rees, the chief executive of the National Pharmacy Association said “Supply shortages are a real and present danger to those patients who rely on life-saving medicines for their wellbeing. Pharmacy teams have seen the problems get worse in this country over recent years, putting more patients at risk." “Pharmacists … are spending hours a day hunting down stock, yet too often have to turn patients away. It’s distressing when pharmacy teams find themselves unable to provide prompt medicines services, through no fault of their own,” he added. What are the reasons for medicine shortage in UK? While global factors like the COVID-19 pandemic, inflation, and the war in Ukraine have contributed to the drug shortages, Brexit has significantly worsened the situation. The UK's departure from the EU has disrupted the smooth flow of medicines, leading to delays and uncertainties in drug supply chains. “A clear picture emerged of underlying fragilities at a global and UK level, not fundamentally rooted in Brexit but exacerbated by it in some specific ways, especially through some companies removing the UK from their supply chains,” the study read. The Royal Pharmaceutical Society recommended legislative reforms that would allow community pharmacists to issue alternate prescriptions when certain pharmaceuticals are unavailable. The Department of Health and Social Care (DHSC) said that the majority of pharmaceuticals are still available and that concessionary pricing are not always connected to shortages.

UK faces 'new normal' of medicine supply shortage post-Brexit: Report

There is now a shortage&nbsp;of cancer medicines in the United States.&nbsp;It has gotten to the point that some treatment facilities have had to substitute patients' medications and, in some cases, even postpone treatment.

<h2>Why is this shortage? What are the consequences?</h2>

As per&nbsp;NBC reports, over a dozen medications have been witnessing limited supply in the United States in recent months.&nbsp;These include the anticancer drugs carboplatin and cisplatin, which are commonly used to treat non-small-cell lung cancer as well as testicular, gynecologic, breast, bladder, head, and neck malignancies.&nbsp;Around 10-20 per cent&nbsp;of all cancer patients are treated with cisplatin and similar medications, as reported by the NBC.

As per&nbsp;a study conducted by the National Comprehensive Cancer Network last month, carboplatin and cisplatin were in insufficient supply at almost all of the centres.

A California cancer patient who was denied&nbsp;access to cisplatin in April by his insurance provider cited the major scarcity in a Financial Times interview.

"Currently, cisplatin is only permitted for malignancies that can be cured." Michael Griffith, a 51-year-old father of three, explained that his disease is incurable.&nbsp;"Thus I am not currently eligible for it," he said.

As per&nbsp;the University of Utah Drug Information Service, which was cited by CNN, about 20 chemo medicines were difficult to procure&nbsp;by the end of March.

The CEO of the National Comprehensive Cancer Network, Dr&nbsp;Robert Carlson, was reported by CNN as stating, "This is an untenable scenario. We are hearing from oncologists and chemists all throughout the nation who are currently rushing to discover suitable options for treating their cancer patients."

Also read |&nbsp;<a href="https://www.wionews.com/science/oral-sex-emerges-as-major-risk-factor-for-throat-cancer-claims-study-587149">Oral sex emerges as major risk factor for throat cancer, claims study</a>

More than a third of cancer centres with carboplatin shortages claimed they were unable to treat every patient using the recommended dose and timing.

“We were relieved by survey results that show patients are still able to get life-saving care, but it comes at a burden to our overtaxed medical facilities,” Carlson told CNN.

“We need to work together to improve the current situation and prevent it from happening again in the future,” he explained .&nbsp;

<h2>Ramifications of switching cancer medicines</h2>

Switching cancer medications has actual ramifications.&nbsp;According to Jennifer Rubatt, an oncology specialist in Denver, Colorado, "In late April and May, I had to make drug substitutions for newly diagnosed ovarian cancer patients because we did not have the sort of first-choice drugs available," she stated in an interview with the Financial Times.

In the words of Mike Ganio, a researcher at the American Society of Health-System Pharmacists who focuses on drug shortages, the issue began to emerge earlier this year.

“I think it went from being a shortage to being a really bad shortage really quickly,” he told the Associated Press.

A facility in India that manufactures both medications halted production after an inspection revealed quality issues, prompting Ganio's organisation to notify the lack of cisplatin in January and the shortfall of carboplatin in late March.

The producer Intas Pharmaceuticals provides around half of the market share for cisplatin, according to Erin Fox, senior pharmacy director at University of Utah Health and an expert on medication shortages.

Also read |&nbsp;<a href="https://www.wionews.com/science/long-covid-patients-have-lower-quality-of-life-than-those-with-cancer-parkinsons-disease-study-602160">Long Covid patients have lower quality of life than those with cancer, Parkinson’s disease: Study</a>

<h2>What's the consequence?</h2>

In an effort to address the chemotherapeutic shortage, the US Food and Drug Administration has taken some action.

The organisation is permitting the temporary importation of select cisplatin formulations that have received foreign approval from businesses that have registered with the FDA.

The FDA has authorised cisplatin maker Qilu Pharmaceutical to ship the medication to the United States, according to CNBC.

As per&nbsp;NBC reports, the medication, which comes in 50-milligram bottles, will be exported to the US and distributed by Qilu and Canadian pharmaceutical company Apotex.

The End Drug Shortages Alliance's board chair, Eric Tichy, was reported by the publication as calling this a "good plan."

"It will hopefully help more patients access product and not have their treatments delayed," Fox told USA Today.

FDA commissioner Dr Robert Califf tweeted, “​​The public should rest assured that we will continue all efforts within our authority to help the industry that manufactures and distributes these drugs meet all patient needs for the oncology drugs impacted by shortages.”

Also watch |&nbsp;Gravitas | Study: Yoga cuts the risk of Cancer spreading in the body

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The facility in India has to be brought back up to full output, according to Ganio, who added that while that should assist.

Intas received a letter last week from the US Food and Drug Administration permitting it to continue delivering a number of medications, including cisplatin and carboplatin, according to USA Today.

FDA says&nbsp;Intas will be required to conduct independent product testing and reviews.

(With inputs from agencies) 
 
&nbsp;

WATCH WION LIVE HERE:

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There is now a shortage of cancer medicines in the United States. It has gotten to the point that some treatment facilities have had to substitute patients' medications and, in some cases, even postpone treatment.

There is now a shortage of cancer medicines in the United States. It has gotten to the point that some treatment facilities have had to substitute patients' medications and, in some cases, even postpone treatment. Why is this shortage? What are the consequences? As per NBC reports, over a dozen medications have been witnessing limited supply in the United States in recent months. These include the anticancer drugs carboplatin and cisplatin, which are commonly used to treat non-small-cell lung cancer as well as testicular, gynecologic, breast, bladder, head, and neck malignancies. Around 10-20 per cent of all cancer patients are treated with cisplatin and similar medications, as reported by the NBC. As per a study conducted by the National Comprehensive Cancer Network last month, carboplatin and cisplatin were in insufficient supply at almost all of the centres. A California cancer patient who was denied access to cisplatin in April by his insurance provider cited the major scarcity in a Financial Times interview. "Currently, cisplatin is only permitted for malignancies that can be cured." Michael Griffith, a 51-year-old father of three, explained that his disease is incurable. "Thus I am not currently eligible for it," he said. As per the University of Utah Drug Information Service, which was cited by CNN, about 20 chemo medicines were difficult to procure by the end of March. The CEO of the National Comprehensive Cancer Network, Dr Robert Carlson, was reported by CNN as stating, "This is an untenable scenario. We are hearing from oncologists and chemists all throughout the nation who are currently rushing to discover suitable options for treating their cancer patients." Also read | Oral sex emerges as major risk factor for throat cancer, claims study More than a third of cancer centres with carboplatin shortages claimed they were unable to treat every patient using the recommended dose and timing. “We were relieved by survey results that show patients are still able to get life-saving care, but it comes at a burden to our overtaxed medical facilities,” Carlson told CNN. “We need to work together to improve the current situation and prevent it from happening again in the future,” he explained . Ramifications of switching cancer medicines Switching cancer medications has actual ramifications. According to Jennifer Rubatt, an oncology specialist in Denver, Colorado, "In late April and May, I had to make drug substitutions for newly diagnosed ovarian cancer patients because we did not have the sort of first-choice drugs available," she stated in an interview with the Financial Times. In the words of Mike Ganio, a researcher at the American Society of Health-System Pharmacists who focuses on drug shortages, the issue began to emerge earlier this year. “I think it went from being a shortage to being a really bad shortage really quickly,” he told the Associated Press. A facility in India that manufactures both medications halted production after an inspection revealed quality issues, prompting Ganio's organisation to notify the lack of cisplatin in January and the shortfall of carboplatin in late March. The producer Intas Pharmaceuticals provides around half of the market share for cisplatin, according to Erin Fox, senior pharmacy director at University of Utah Health and an expert on medication shortages. Also read | Long Covid patients have lower quality of life than those with cancer, Parkinson’s disease: Study What's the consequence? In an effort to address the chemotherapeutic shortage, the US Food and Drug Administration has taken some action. The organisation is permitting the temporary importation of select cisplatin formulations that have received foreign approval from businesses that have registered with the FDA. The FDA has authorised cisplatin maker Qilu Pharmaceutical to ship the medication to the United States, according to CNBC. As per NBC reports, the medication, which comes in 50-milligram bottles, will be exported to the US and distributed by Qilu and Canadian pharmaceutical company Apotex. The End Drug Shortages Alliance's board chair, Eric Tichy, was reported by the publication as calling this a "good plan." "It will hopefully help more patients access product and not have their treatments delayed," Fox told USA Today. FDA commissioner Dr Robert Califf tweeted, “The public should rest assured that we will continue all efforts within our authority to help the industry that manufactures and distributes these drugs meet all patient needs for the oncology drugs impacted by shortages.” Also watch | Gravitas | Study: Yoga cuts the risk of Cancer spreading in the body The facility in India has to be brought back up to full output, according to Ganio, who added that while that should assist. Intas received a letter last week from the US Food and Drug Administration permitting it to continue delivering a number of medications, including cisplatin and carboplatin, according to USA Today. FDA says Intas will be required to conduct independent product testing and reviews. (With inputs from agencies) WATCH WION LIVE HERE:

Explained: US faces acute shortage of cancer medication, what are its ramifications?

Pakistan is in the grip of yet another crisis. After food, fuel & forex reserves, the country is running out of medicines. Reports say, medicines like Disprin & Calpol are not available in the market. Molly Gambhir reports.

Gravitas: Medicine shortage grips Pakistan

The economic crisis in Sri Lanka has pushed its health care system to the brink. Residents are struggling to get basic medication and checkups with soaring inflation in the country.

Sri Lanka: Economic crisis pushes health system to the brink, struggles with medicine shortages

An&nbsp;IMF&nbsp;delegation was in&nbsp;Sri&nbsp;Lanka&nbsp;Monday for talks on the island's&nbsp;worsening&nbsp;economic&nbsp;crisis, with the public suffering through months of food, fuel and medicine shortages.

A lack of foreign currency has left traders unable to pay for vital imports in what authorities concede is the South Asian nation's worst financial&nbsp;crisis&nbsp;since independence from Britain in 1948.

Long queues outside gas stations and rolling blackouts have become the norm, while record inflation has caused serious hardship among the island's 22 million people by repeatedly pushing up the cost of groceries, transport and pharmaceuticals.&nbsp;

Also read |&nbsp;<a href="https://www.wionews.com/south-asia/nepal-pm-deuba-to-visit-sri-lanka-for-bimstec-summit-461926">Nepal PM Deuba to visit Sri Lanka for BIMSTEC summit</a>

A senior staffer from the International Monetary Fund "will hold talks" with President Gotabaya Rajapaksa and his brother, finance minister Basil Rajapaksa, a spokesman for the leader told&nbsp;AFP.&nbsp;

Sri&nbsp;Lanka's government is divided on seeking a bailout, but the international lender said it was "ready to&nbsp;discuss&nbsp;options if requested" in a Monday statement.&nbsp;

The&nbsp;IMF&nbsp;warned earlier this month that the country's $51 billion foreign debt was "unsustainable", and called for a currency devaluation and higher taxes to revive its almost bankrupt economy.

Sri&nbsp;Lanka&nbsp;last week allowed the rupee to float, a move that saw the currency nosedive 25 percent against the dollar and triggered a fresh wave of price increases.

Also read |&nbsp;<a href="https://www.wionews.com/south-asia/sri-lankas-central-bank-assures-countrys-currency-to-stabilize-soon-461651">Sri Lanka's central bank assures country's currency to stabilise soon</a>

Fuel costs have risen by nearly 80 percent since early February while food prices rose by a quarter according to January figures.&nbsp;

The coronavirus pandemic hammered the South Asian island's tourism sector -- a key foreign exchange earner.

Sri&nbsp;Lanka&nbsp;needs nearly $7 billion to service its foreign debt this year, but the country's external reserves at the end of January were just over $2 billion -- enough to finance one month of imports.

Watch |&nbsp;Sri Lanka's deepening economic crisis: Fuel prices touch record high

<div class="videoWrapper trancodeVideo"><iframe allowfullscreen="" autoplay="1" class="includeVideo" frameborder="0" height="350" src="https://www.wionews.com/videos/sri-lankas-deepening-economic-crisis-fuel-prices-touch-record-high-461509/embed" style="width:100%;max-width:560px;" width="560"></iframe></div>

International ratings agencies have downgraded&nbsp;Sri&nbsp;Lanka&nbsp;over expectations it may not be able to repay its borrowings, though the government insists it will.

An IMF delegation was in Sri Lanka Monday for talks on the island's worsening economic crisis, with the public suffering through months of food, fuel and medicine shortages.

An IMF delegation was in Sri Lanka Monday for talks on the island's worsening economic crisis, with the public suffering through months of food, fuel and medicine shortages. A lack of foreign currency has left traders unable to pay for vital imports in what authorities concede is the South Asian nation's worst financial crisis since independence from Britain in 1948. Long queues outside gas stations and rolling blackouts have become the norm, while record inflation has caused serious hardship among the island's 22 million people by repeatedly pushing up the cost of groceries, transport and pharmaceuticals. Also read | Nepal PM Deuba to visit Sri Lanka for BIMSTEC summit A senior staffer from the International Monetary Fund "will hold talks" with President Gotabaya Rajapaksa and his brother, finance minister Basil Rajapaksa, a spokesman for the leader told AFP. Sri Lanka's government is divided on seeking a bailout, but the international lender said it was "ready to discuss options if requested" in a Monday statement. The IMF warned earlier this month that the country's $51 billion foreign debt was "unsustainable", and called for a currency devaluation and higher taxes to revive its almost bankrupt economy. Sri Lanka last week allowed the rupee to float, a move that saw the currency nosedive 25 percent against the dollar and triggered a fresh wave of price increases. Also read | Sri Lanka's central bank assures country's currency to stabilise soon Fuel costs have risen by nearly 80 percent since early February while food prices rose by a quarter according to January figures. The coronavirus pandemic hammered the South Asian island's tourism sector -- a key foreign exchange earner. Sri Lanka needs nearly $7 billion to service its foreign debt this year, but the country's external reserves at the end of January were just over $2 billion -- enough to finance one month of imports. Watch | Sri Lanka's deepening economic crisis: Fuel prices touch record high International ratings agencies have downgraded Sri Lanka over expectations it may not be able to repay its borrowings, though the government insists it will.

IMF in Sri Lanka to discuss worsening economic crisis

'You killed my wife!' Man's anger towards Maduro as wife dies due to medicine shortage

Kashmir residents said today they are facing shortages of prescription drugs, as parts of the region remained under curfew for an 11th day following deadly clashes between protesters and security forces. 
 
As the overall death toll from days of violence rose to 45, shopkeepers warned supplies were running low because trucks were unable to reach them, while residents complained of being &quot;caged&quot; in their homes. 
 
&quot;People are suffering without medicines. A lot of people are struggling for medicines for diabetes, hypertension and anti-depressants,&quot; said Nazir Ahmed who owns a pharmacy in the old part of the main city of Srinagar. 
 
With most vehicles ordered off the roads under the curfew, Ahmed said he walked five kilometres to a warehouse to buy medicines. 
 
&quot;No fresh supplies are coming from outside. This will last two to three days for my neighbourhood,&quot; Ahmed said, carrying plastic bags full of medicines. 
 
Shops and other businesses have been shuttered under the curfew which the government says is needed to curb the street clashes that erupted after the death of a Hizbul Mujahideen commander on July 8. 
 
Burhan Wani, killed during a gunbattle with government forces, was commander of the region&#39;s biggest separatist group Hizbul Mujahideen, listed as a terror group by India, United States and the European Union among others, one of several fighting for decades against Indian troops deployed in the territory. 
 
The clashes are the deadliest in Muslim-majority Kashmir since 2010 when massive demonstrations were held against Indian rule. 
 
Kashmir has been divided between rivals India and Pakistan since independence in 1947, but both claim the Himalayan territory in full. 
 
In the latest violence two protesters were killed late Monday when soldiers opened fire on stone-throwing demonstrators in the south. 
 
The army said in a statement troops were forced to shoot when a &quot;large mob turned violent&quot; and &quot;attempted to snatch weapons from the soldiers&quot;, adding that the deaths were regretted. 
 
In parts of Srinagar today, residents kept watch for volunteers from local charities delivering supplies including food on foot. 
 
An elderly woman suffering from hypertension and a heart condition said she hoped they would bring medicines soon. 
 
&quot;I don&#39;t have my medicines. Some volunteers came, but they did not have the medicines I need,&quot; Noora, 80, who uses one name, said from her doorstep. 
 
&quot;We are just caged inside our home,&quot; her son, Ghulam Nabi Ahangar, added. 
 
Ahangar said security forces were firing tear gas and pepper spray at night to deter people from venturing outside. 
 
&quot;The poisonous gases stay inside our home and lungs the whole night. Our children are falling sick and cannot sleep,&quot; Ahangar told AFP. 
 
Some pharmacies outside hospitals are open but few residents can reach them, while internet and phone services remain patchy. 
 
&quot;Patients who have not been able to reach hospitals will come in large numbers once the curfew is lifted. It will be another huge emergency,&quot; said Kaisar Ahmed, head of Sri Maharaja Hari Singh Hospital and six other government hospitals in Srinagar. 
 
(AFP)

Shopkeepers warned supplies were running low as trucks were unable to reach them. Residents complained of being 'caged' in their homes

Kashmir residents said today they are facing shortages of prescription drugs, as parts of the region remained under curfew for an 11th day following deadly clashes between protesters and security forces. As the overall death toll from days of violence rose to 45, shopkeepers warned supplies were running low because trucks were unable to reach them, while residents complained of being "caged" in their homes. "People are suffering without medicines. A lot of people are struggling for medicines for diabetes, hypertension and anti-depressants," said Nazir Ahmed who owns a pharmacy in the old part of the main city of Srinagar. With most vehicles ordered off the roads under the curfew, Ahmed said he walked five kilometres to a warehouse to buy medicines. "No fresh supplies are coming from outside. This will last two to three days for my neighbourhood," Ahmed said, carrying plastic bags full of medicines. Shops and other businesses have been shuttered under the curfew which the government says is needed to curb the street clashes that erupted after the death of a Hizbul Mujahideen commander on July 8. Burhan Wani, killed during a gunbattle with government forces, was commander of the region's biggest separatist group Hizbul Mujahideen, listed as a terror group by India, United States and the European Union among others, one of several fighting for decades against Indian troops deployed in the territory. The clashes are the deadliest in Muslim-majority Kashmir since 2010 when massive demonstrations were held against Indian rule. Kashmir has been divided between rivals India and Pakistan since independence in 1947, but both claim the Himalayan territory in full. In the latest violence two protesters were killed late Monday when soldiers opened fire on stone-throwing demonstrators in the south. The army said in a statement troops were forced to shoot when a "large mob turned violent" and "attempted to snatch weapons from the soldiers", adding that the deaths were regretted. In parts of Srinagar today, residents kept watch for volunteers from local charities delivering supplies including food on foot. An elderly woman suffering from hypertension and a heart condition said she hoped they would bring medicines soon. "I don't have my medicines. Some volunteers came, but they did not have the medicines I need," Noora, 80, who uses one name, said from her doorstep. "We are just caged inside our home," her son, Ghulam Nabi Ahangar, added. Ahangar said security forces were firing tear gas and pepper spray at night to deter people from venturing outside. "The poisonous gases stay inside our home and lungs the whole night. Our children are falling sick and cannot sleep," Ahangar told AFP. Some pharmacies outside hospitals are open but few residents can reach them, while internet and phone services remain patchy. "Patients who have not been able to reach hospitals will come in large numbers once the curfew is lifted. It will be another huge emergency," said Kaisar Ahmed, head of Sri Maharaja Hari Singh Hospital and six other government hospitals in Srinagar. (AFP)

Kashmir unrest: Residents under curfew face medicine shortage

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