<p>New research suggests that brain fog experienced by individuals with long Covid may be linked to leaky blood vessels. Scientists suggest that coronavirus disrupts a person's blood-brain barrier, which could be a potential cause of the cognitive issues seen in those with long Covid.</p>

<h2><strong>The research</strong></h2>

<p>A team from Trinity College Dublin and FutureNeuro, a research centre, examined serum and plasma samples from 76 individuals hospitalised with COVID-19 in March or April 2020. In addition, they analysed the samples from 25 people before the pandemic.</p>

<p>Their findings, which have been published in Nature Neuroscience, revealed that individuals with long COVID who exhibited blood-brain barrier leaks experienced brain fog. On the other hand, those without the said disruptions did not.</p>

<p><strong>Also read |&nbsp;<a href="https://www.wionews.com/health-and-wellness/rising-cases-of-silent-heart-attacks-linked-to-long-covid-wion-decodes-687662">Rising cases of silent heart attacks linked to long Covid? WION decodes</a></strong></p>

<p>Professor Matthew Campbell, a geneticist and head of genetics at Trinity, who contributed to the study said that "for the first time...we have been able to show that leaky blood vessels in the human brain, in tandem with a hyperactive immune system, may be the key drivers of brain fog associated with long COVID."</p>

<p>"This is critically important, as understanding the underlying cause of these conditions will allow us to develop targeted therapies for patients in the future," he added, as quoted by Sky News.</p>

<p>In their report, the researchers highlighted that "disruption" is apparent during "acute infection and in patients with long COVID with cognitive impairment." Still, they noted that it remains unclear how function is affected in these conditions.</p>

<p><strong>Also read |&nbsp;<a href="https://www.wionews.com/science/people-with-long-covid-shouldnt-undertake-intense-exercise-study-676565">People with long Covid shouldn't undertake intense exercise: Study</a></strong></p>

<p>Previously, a study from University College London noted that blood vessel leakage into surrounding tissues is common in numerous inflammatory diseases.</p>

<p>Professor Colin Doherty, a neurology expert and head of the school of medicine at Trinity, who was not part of the study, suggests that the study results will "now likely change the landscape of how we understand and treat post-viral neurological conditions".</p>

<p>"It also confirms that the neurological symptoms of long COVID are measurable with real and demonstrable metabolic and vascular changes in the brain," he added.</p>

<p><strong>Watch |&nbsp;Covid study: Indians suffer more lung damage post recovery, worst-hit by Covid after-effects</strong></p>

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<h2><strong>What is long covid?</strong></h2>

<p>Individuals with persistent symptoms such as tiredness, difficulty breathing, memory and cognitive issues, as well as joint and muscle pain lasting more than 12 weeks after infection, can be classified as having long COVID.</p>

<p>According to the Office for National Statistics, as of March last year, an estimated 1.9 million people in the UK living in private households, accounting for 2.9 per cent of the population, were experiencing self-reported long COVID.</p>

<p><em>(With inputs from agencies)</em></p>


New research suggests that brain fog experienced by individuals with long Covid may be linked to leaky blood vessels. Scientists suggest that coronavirus disrupts a person's blood-brain barrier, which could be a potential cause of the cognitive issues seen in those with long Covid.

New research suggests that brain fog experienced by individuals with long Covid may be linked to leaky blood vessels. Scientists suggest that coronavirus disrupts a person's blood-brain barrier, which could be a potential cause of the cognitive issues seen in those with long Covid. The research A team from Trinity College Dublin and FutureNeuro, a research centre, examined serum and plasma samples from 76 individuals hospitalised with COVID-19 in March or April 2020. In addition, they analysed the samples from 25 people before the pandemic. Their findings, which have been published in Nature Neuroscience, revealed that individuals with long COVID who exhibited blood-brain barrier leaks experienced brain fog. On the other hand, those without the said disruptions did not. Also read | Rising cases of silent heart attacks linked to long Covid? WION decodes Professor Matthew Campbell, a geneticist and head of genetics at Trinity, who contributed to the study said that "for the first time...we have been able to show that leaky blood vessels in the human brain, in tandem with a hyperactive immune system, may be the key drivers of brain fog associated with long COVID." "This is critically important, as understanding the underlying cause of these conditions will allow us to develop targeted therapies for patients in the future," he added, as quoted by Sky News. In their report, the researchers highlighted that "disruption" is apparent during "acute infection and in patients with long COVID with cognitive impairment." Still, they noted that it remains unclear how function is affected in these conditions. Also read | People with long Covid shouldn't undertake intense exercise: Study Previously, a study from University College London noted that blood vessel leakage into surrounding tissues is common in numerous inflammatory diseases. Professor Colin Doherty, a neurology expert and head of the school of medicine at Trinity, who was not part of the study, suggests that the study results will "now likely change the landscape of how we understand and treat post-viral neurological conditions". "It also confirms that the neurological symptoms of long COVID are measurable with real and demonstrable metabolic and vascular changes in the brain," he added. Watch | Covid study: Indians suffer more lung damage post recovery, worst-hit by Covid after-effects × What is long covid? Individuals with persistent symptoms such as tiredness, difficulty breathing, memory and cognitive issues, as well as joint and muscle pain lasting more than 12 weeks after infection, can be classified as having long COVID. According to the Office for National Statistics, as of March last year, an estimated 1.9 million people in the UK living in private households, accounting for 2.9 per cent of the population, were experiencing self-reported long COVID. (With inputs from agencies)

Research finds connection between long Covid brain fog and leaky blood vessels

<p>COVID infection that lasts for a prolonged duration, even if it is minor, may have dire consequences for patients and may increase the risk of heart attacks, brain strokes and even dementia, experts have warned.</p>

<p>This comes as growing cases of long Covid are being reported globally. According to a recent study, occurrences of neurological diseases and heart-related problems have increased by 60 per cent in patients with Covid.</p>

<h2>What is Long Covid?</h2>

<p>Patients with this particular type of Covid infection continue to have symptoms for an extended period of time—more than the typical 14–15 days.</p>

<p><strong>Watch |&nbsp;Gravitas: Can long COVID be linked to dementia?</strong></p>

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<h2>What did the experts say?</h2>

<p>Dr Ashok Seth, Chairman of Fortis Escorts Heart Institute, told ANI that there is a significant amount of data from the west that shows that heart attacks and strokes increased by 60 per cent over the course of a year in hundreds of thousands of patients studied.</p>

<p>"So we are very clear COVID, even though mild, may affect people for a longer duration up to a year and create increased incidents of heart attacks and strokes."</p>

<p><strong>Also read |&nbsp;<a href="https://www.wionews.com/world/xi-jinpings-zero-covid-policy-faces-rare-public-criticism-511536">Xi Jinping's 'zero-covid' policy faces rare public criticism</a></strong></p>

<p>According to Dr Padma Srivastava, professor and senior neurologist at AIIMS in Delhi, COVID has developed over time to affect the brain and the nervous system in addition to the lungs.</p>

<p>"We also now know that there is a definitive entity called long Covid which means there are features which are coming up, persisting after Covid infection in three months. There is extensive research which is going on, all over the world," she said talking to ANI.</p>

<h2><strong>How can it affect us?</strong></h2>

<p>As per Dr Srivastava when it comes to Covid, there are several factors at play, including infection, inflammation, involvement of the brain, nervous system, muscles, and peripheral central nervous system.</p>

<p><strong>Also read |&nbsp;<a href="https://www.wionews.com/world/long-covid-symptoms-affect-1-in-8-suggests-lancet-study-503936">Long COVID symptoms affect 1 In 8, suggests Lancet Study</a></strong></p>

<p>She warned that when it comes to the brain, Covid can give way to "immediate acute situations" like a brain attack or a stroke and inflammation.</p>

<p>Another risk is that these people could develop dementia or Parkinson's disease-like symptoms, however, research is still being done to see if that's likely.</p>

<p><em>(With inputs from agencies)</em></p>

<p><strong>WATCH WION LIVE HERE</strong></p>

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<p>You can <strong>now write for wionews.com</strong> and be a part of the community. Share your stories and opinions with us <strong><a href="https://www.wionews.com/content-contribution-registration-form">here</a>.</strong></p>


COVID infection that lasts for a prolonged duration, even if it is minor, may have dire consequences for patients and may increase the risk of heart attacks, brain strokes and even dementia, experts have warned.

COVID infection that lasts for a prolonged duration, even if it is minor, may have dire consequences for patients and may increase the risk of heart attacks, brain strokes and even dementia, experts have warned. This comes as growing cases of long Covid are being reported globally. According to a recent study, occurrences of neurological diseases and heart-related problems have increased by 60 per cent in patients with Covid. What is Long Covid? Patients with this particular type of Covid infection continue to have symptoms for an extended period of time—more than the typical 14–15 days. Watch | Gravitas: Can long COVID be linked to dementia? What did the experts say? Dr Ashok Seth, Chairman of Fortis Escorts Heart Institute, told ANI that there is a significant amount of data from the west that shows that heart attacks and strokes increased by 60 per cent over the course of a year in hundreds of thousands of patients studied. "So we are very clear COVID, even though mild, may affect people for a longer duration up to a year and create increased incidents of heart attacks and strokes." Also read | Xi Jinping's 'zero-covid' policy faces rare public criticism According to Dr Padma Srivastava, professor and senior neurologist at AIIMS in Delhi, COVID has developed over time to affect the brain and the nervous system in addition to the lungs. "We also now know that there is a definitive entity called long Covid which means there are features which are coming up, persisting after Covid infection in three months. There is extensive research which is going on, all over the world," she said talking to ANI. How can it affect us? As per Dr Srivastava when it comes to Covid, there are several factors at play, including infection, inflammation, involvement of the brain, nervous system, muscles, and peripheral central nervous system. Also read | Long COVID symptoms affect 1 In 8, suggests Lancet Study She warned that when it comes to the brain, Covid can give way to "immediate acute situations" like a brain attack or a stroke and inflammation. Another risk is that these people could develop dementia or Parkinson's disease-like symptoms, however, research is still being done to see if that's likely. (With inputs from agencies) WATCH WION LIVE HERE You can now write for wionews.com and be a part of the community. Share your stories and opinions with us here.

Long Covid can give way to neurological problems like brain strokes, inflammation and even dementia: Experts

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<p>A new <a href="https://www.eurekalert.org/news-releases/947495">study </a>found that the various symptoms connected to long COVID-19 could be different in people, who have been infected with different variants of the deadly virus.&nbsp;</p>

<p>The study, based on long Covid and all the symptoms associated with it, will be presented at<strong>&nbsp;</strong>the European Congress of Clinical Microbiology &amp; Infectious Diseases (ECCMID 2022) in Lisbon next month.&nbsp;</p>

<p>As per the study, estimates have suggested that over half of survivors of SARS-CoV-2 infection experience post-acute sequelae of COVID-19 (PASC), more commonly known as 'long COVID'.&nbsp;</p>

<p>From old to young, otherwise healthy to those with underlying conditions, the study mentioned that the condition can affect anyone.&nbsp;</p>

<p><strong>ALSO READ |&nbsp;<a href="https://www.wionews.com/world/us-may-release-billions-of-genetically-modified-male-mosquitoes-heres-why-465936">US may release billions of genetically modified male mosquitoes. Here's why</a></strong></p>

<p>It has been seen in people who were hospitalised with COVID-19 and those with mild symptoms. But despite an increasing body of literature, long COVID remains poorly understood.&nbsp;</p>

<p>Italian researchers did an observational study of 428 patients (254 (59%) men and 174 (41%) women) treated at the Careggi University Hospital's post-COVID outpatient service between June 2020 and June 2021.&nbsp;</p>

<p>It was time when the original form of SARS-CoV-2 and the Alpha variant were circulating in the population.&nbsp;</p>

<p>The researchers have suggested that individuals who were infected with the alpha variant of the virus displayed, an early release from the ECCMID<strong>&nbsp;</strong>regarding the study.&nbsp;</p>

<p>As per the research, individuals who were infected with the alpha variant of the virus displayed different emotional and neurological symptoms.&nbsp;</p>

<p><strong>ALSO READ |&nbsp;<a href="https://www.wionews.com/science/study-shows-several-bird-species-nesting-and-laying-eggs-almost-a-month-early-465532">Study shows several bird species nesting and laying eggs almost a month early</a></strong></p>

<p>On the other hand, those who were infected with the original form of SARS-CoV-2 showed different symptoms.&nbsp;</p>

<p>The study revealed that at least three-quarters 325/428 (76%) of patients reported at least one persistent symptom.&nbsp;</p>

<p>The most common reported symptoms were shortness of breath and chronic fatigue followed by sleep problems, visual problems and brain fog.&nbsp;</p>

<p>The study performed a more detailed evaluation and compared the symptoms reported by patients infected between March and December 2020 (when the original SARS-COV-2 was dominant) with those reported by patients infected between January and April 2021 (when Alpha was the dominant variant).&nbsp;</p>

<p>The researchers found a substantial change in the pattern of neurological and cognitive/emotional problems.&nbsp;</p>

<p>The study has been led by Dr Michele Spinicci and colleagues from the University of Florence and Careggi University Hospital in Italy.&nbsp;</p>

<p>Dr Spinicci said, "Many of the symptoms reported in this study have been measured, but this is the first time they have been linked to different COVID-19 variants."&nbsp;</p>

<p>"The long duration and broad range of symptoms reminds us that the problem is not going away, and we need to do more to support and protect these patients in the long term. Future research should focus on the potential impacts of variants of concern and vaccination status on ongoing symptoms," Dr Spinicci added.&nbsp;</p>

<p><strong>WATCH |&nbsp;China battles worst covid-19 wave, Shanghai imposes phased covid-19 lockdown</strong></p>

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A new study found that the various symptoms connected to long COVID-19 could be different in people, who have been infected with different variants of the deadly virus.

A new study found that the various symptoms connected to long COVID-19 could be different in people, who have been infected with different variants of the deadly virus. The study, based on long Covid and all the symptoms associated with it, will be presented at the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2022) in Lisbon next month. As per the study, estimates have suggested that over half of survivors of SARS-CoV-2 infection experience post-acute sequelae of COVID-19 (PASC), more commonly known as 'long COVID'. From old to young, otherwise healthy to those with underlying conditions, the study mentioned that the condition can affect anyone. ALSO READ | US may release billions of genetically modified male mosquitoes. Here's why It has been seen in people who were hospitalised with COVID-19 and those with mild symptoms. But despite an increasing body of literature, long COVID remains poorly understood. Italian researchers did an observational study of 428 patients (254 (59%) men and 174 (41%) women) treated at the Careggi University Hospital's post-COVID outpatient service between June 2020 and June 2021. It was time when the original form of SARS-CoV-2 and the Alpha variant were circulating in the population. The researchers have suggested that individuals who were infected with the alpha variant of the virus displayed, an early release from the ECCMID regarding the study. As per the research, individuals who were infected with the alpha variant of the virus displayed different emotional and neurological symptoms. ALSO READ | Study shows several bird species nesting and laying eggs almost a month early On the other hand, those who were infected with the original form of SARS-CoV-2 showed different symptoms. The study revealed that at least three-quarters 325/428 (76%) of patients reported at least one persistent symptom. The most common reported symptoms were shortness of breath and chronic fatigue followed by sleep problems, visual problems and brain fog. The study performed a more detailed evaluation and compared the symptoms reported by patients infected between March and December 2020 (when the original SARS-COV-2 was dominant) with those reported by patients infected between January and April 2021 (when Alpha was the dominant variant). The researchers found a substantial change in the pattern of neurological and cognitive/emotional problems. The study has been led by Dr Michele Spinicci and colleagues from the University of Florence and Careggi University Hospital in Italy. Dr Spinicci said, "Many of the symptoms reported in this study have been measured, but this is the first time they have been linked to different COVID-19 variants." "The long duration and broad range of symptoms reminds us that the problem is not going away, and we need to do more to support and protect these patients in the long term. Future research should focus on the potential impacts of variants of concern and vaccination status on ongoing symptoms," Dr Spinicci added. WATCH | China battles worst covid-19 wave, Shanghai imposes phased covid-19 lockdown ×

Different variants may cause different long COVID-19 symptoms, says study