The issue of obesity affects millions of people worldwide. In the latest study, researchers found that one gene called DENND1B drives some Labrador Retrievers to overeat and gain weight. The same gene is also found in humans.&nbsp;
The study published in the journal Science revealed that British Labrador Retrievers have multiple genes related to canine obesity.&nbsp;
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The study found that some Labrador Retrievers don&rsquo;t know when to stop when it comes to hunger eating, and they also have multiple genes associated with canine obesity. The study revealed that the same genes found in these perennially hungry hounds are also associated with obesity in humans.&nbsp;
The researchers performed a canine genome-wide association study for body condition score, which is a measure of obesity, in 241 Labrador Retrievers.&nbsp;
They used a cross-species approach to show canine obesity genes are also associated with rare and common forms of obesity in humans.&nbsp;
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The study found that lead canine association was within the gene DENN domain containing 1B (DENND1B) and each copy of the alternate allele was associated with ~7% greater body fat.&nbsp;
"We demonstrate a role for this gene in regulating signaling and trafficking of melanocortin 4 receptor, a critical controller of energy homeostasis. Thus, canine genetics identified obesity genes and mechanisms relevant to both dogs and humans," the authors said in the study.&nbsp;
As quoted by BBC, lead researcher Dr Eleanor Raffan from the University of Cambridge's Department of Physiology, Development, and Neuroscience, explained, "By studying dogs, we've honed in on some interesting new biology here."&nbsp;
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She further added that the discovery showed that "owners of slim dogs are not morally superior - and the same is true of slim people".&nbsp;
"If you have a high genetic risk of obesity, you're prone to gaining weight unless you put a huge effort into not doing so. And those with low genetic risk just don't have to work so hard."&nbsp;
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The study found that DENND1B was associated with a higher body mass in the Labradors. The researchers then searched through a library of genetic information from thousands of humans, and they were surprised to see that the same gene was associated with a higher body mass in people.&nbsp;
"No one suspected that gene had anything to do with obesity" before this study of Labrador genetics, Dr Raffan said, further adding, "It alters the predisposition to weight gain because it's tweaking a system that is involved in regulating how hungry we feel and how much energy we burn off."

Science & Tech | Learn about the canine genome-wide association study revealing obesity genes. The research identifies DENNDB as a key factor in energy regulation for both species.

The issue of obesity affects millions of people worldwide. In the latest study, researchers found that one gene called DENND1B drives some Labrador Retrievers to overeat and gain weight. The same gene is also found in humans. The study published in the journal Science revealed that British Labrador Retrievers have multiple genes related to canine obesity. Also read: WhatsApp admin killed for removing member from group in Pakistan The study found that some Labrador Retrievers don’t know when to stop when it comes to hunger eating, and they also have multiple genes associated with canine obesity. The study revealed that the same genes found in these perennially hungry hounds are also associated with obesity in humans. The researchers performed a canine genome-wide association study for body condition score, which is a measure of obesity, in 241 Labrador Retrievers. They used a cross-species approach to show canine obesity genes are also associated with rare and common forms of obesity in humans. Also read: 3D-printed penis implant invented to restore erectile function: Study The study found that lead canine association was within the gene DENN domain containing 1B (DENND1B) and each copy of the alternate allele was associated with ~7% greater body fat. "We demonstrate a role for this gene in regulating signaling and trafficking of melanocortin 4 receptor, a critical controller of energy homeostasis. Thus, canine genetics identified obesity genes and mechanisms relevant to both dogs and humans," the authors said in the study. As quoted by BBC, lead researcher Dr Eleanor Raffan from the University of Cambridge's Department of Physiology, Development, and Neuroscience, explained, "By studying dogs, we've honed in on some interesting new biology here." Also read: 'Floodlighting': A new toxic dating trend is emerging. Have you experienced it? She further added that the discovery showed that "owners of slim dogs are not morally superior - and the same is true of slim people". "If you have a high genetic risk of obesity, you're prone to gaining weight unless you put a huge effort into not doing so. And those with low genetic risk just don't have to work so hard." Also read: Hey, woman, painkillers won’t help you the way they help men The study found that DENND1B was associated with a higher body mass in the Labradors. The researchers then searched through a library of genetic information from thousands of humans, and they were surprised to see that the same gene was associated with a higher body mass in people. "No one suspected that gene had anything to do with obesity" before this study of Labrador genetics, Dr Raffan said, further adding, "It alters the predisposition to weight gain because it's tweaking a system that is involved in regulating how hungry we feel and how much energy we burn off."

You and your Labrador Retriever may share same gene linked to obesity: Study

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In a new study, published in the journal Science, scientists have found that a dog's breed cannot predict its behaviour.

Researchers conducted a survey on more than 2,000 dogs to assess their behavioral traits and genes.

From&nbsp;their analysis, they prepared 200,000 survey answers from those who either owned dogs or had adopted them.

They took their data from Darwin's Ark, an open-source database of owner-reported canine traits and behaviors.&nbsp;

<div class="videoWrapper trancodeVideo"><iframe allowfullscreen="" autoplay="1" class="includeVideo" frameborder="0" height="350" src="https://www.wionews.com/videos/dogs-owners-race-through-the-snow-in-russia-449706/embed" style="width:100%;max-width:560px;" width="560"></iframe></div>

Through it, they found that the modern concept of breed offers only partial predictive value for most types of behaviour.

And although many many behavioral traits can be inherited through genes but they cannot determine how affectionate a dog will be, or conversely, how quick to anger.

According to Elinor Karlsson, of UMass Chan and the Broad Institute of MIT and Harvard, who is among one of the authors of the generic study, "While genetics plays a role in the personality of any individual dog, the specific dog breed is not a good predictor of those traits."

"What we found is that the defining criteria of a golden retriever are its physical characteristics, the shape of its ears, the color and quality of its fur, its size, not whether it is friendly," she added.

<a href="https://www.wionews.com/world/patron-a-ukrainian-service-dog-who-discovered-150-explosives-in-chernihiv-during-war-473649">Also read |&nbsp;Patron - A Ukrainian service dog who 'discovered 150 explosives' in Chernihiv during war</a>

Scientists believe that it is crucial to understand the relationship between breeds and behavior for psychiatric conditions in humans, like obsessive disorders.

"Although we can't really ask a dog themselves about their problems or thoughts or anxieties, we do know that dogs lead rich emotional lives and experience disorders that manifests in their behavior," lead author Kathleen Morrill told AFP news agency.

It is a common stereotype to believe that rottweilers and pit bulls are aggressive, while Labradors and golden retrievers are extra friendly.

"When we looked at this factor that we called agonistic threshold, which included a lot of questions about whether people's dogs reacted aggressively to things, we weren't seeing an effect of breed ancestry," Karlsson added.

During the study, scientists also found out that Labradors the lowest propensity for howling and 90 per cent of greyhounds don't bury their toys.

"It could be that understanding human sociability in dogs helps us understand how brains develop and learn. So we're kind of just scratching the surface," said Morill.

Watch WION's live TV here

<iframe allow="accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture" allowfullscreen="" frameborder="0" height="350" src="https://www.wionews.com/live-tv/embed?autoplay=1&amp;mute=1" width="100%"></iframe>

(With inputs from agencies)

In a new study, published in the journal Science, scientists have found that a dog's breed cannot predict its behaviour. Researchers conducted a survey on more than 2,000 dogs to assess their behavioral traits and genes.

In a new study, published in the journal Science, scientists have found that a dog's breed cannot predict its behaviour. Researchers conducted a survey on more than 2,000 dogs to assess their behavioral traits and genes. From their analysis, they prepared 200,000 survey answers from those who either owned dogs or had adopted them. They took their data from Darwin's Ark, an open-source database of owner-reported canine traits and behaviors. Through it, they found that the modern concept of breed offers only partial predictive value for most types of behaviour. And although many many behavioral traits can be inherited through genes but they cannot determine how affectionate a dog will be, or conversely, how quick to anger. According to Elinor Karlsson, of UMass Chan and the Broad Institute of MIT and Harvard, who is among one of the authors of the generic study, "While genetics plays a role in the personality of any individual dog, the specific dog breed is not a good predictor of those traits." "What we found is that the defining criteria of a golden retriever are its physical characteristics, the shape of its ears, the color and quality of its fur, its size, not whether it is friendly," she added. Also read | Patron - A Ukrainian service dog who 'discovered 150 explosives' in Chernihiv during war Scientists believe that it is crucial to understand the relationship between breeds and behavior for psychiatric conditions in humans, like obsessive disorders. "Although we can't really ask a dog themselves about their problems or thoughts or anxieties, we do know that dogs lead rich emotional lives and experience disorders that manifests in their behavior," lead author Kathleen Morrill told AFP news agency. It is a common stereotype to believe that rottweilers and pit bulls are aggressive, while Labradors and golden retrievers are extra friendly. "When we looked at this factor that we called agonistic threshold, which included a lot of questions about whether people's dogs reacted aggressively to things, we weren't seeing an effect of breed ancestry," Karlsson added. During the study, scientists also found out that Labradors the lowest propensity for howling and 90 per cent of greyhounds don't bury their toys. "It could be that understanding human sociability in dogs helps us understand how brains develop and learn. So we're kind of just scratching the surface," said Morill. Watch WION's live TV here (With inputs from agencies)

Scientists say that a dog's breed cannot predict its behaviour

A chocolate Labrador in the Colombian city of Medellin is staying busy during the pandemic by working as a delivery dog for his owner's convenience store. Eros might not know that he's become an essential worker. But he is happy to help his owners and collect his daily pay.

Labrador helps Colombian store keep distancing measures

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