Billionaire and 'biohacker' Bryan Johnson, "who wants to live forever", has revealed in a new YouTube video that he may have accidentally sped up his aging process rather than slowing it down. Notably, Johnson spends $2 million a year to reverse his biological age.
In a new video posted on his YouTube channel, Johnson revealed a significant error concerning rapamycin, a immunosuppressant, popular in anti-aging circles. Johnson modified the dosage after testing and reseraching on rapamycin to manage potential benefits and risks. However, instead of experiencing rejuvenation, the tech entrepreneur began noticing side effects.&nbsp;
Read More | <a href="https://www.wionews.com/trending/what-is-this-anti-ageing-drug-brayan-johnson-is-warning-about-8624001" rel="dofollow">What is this 'anti-ageing' drug Bryan Johnson is warning about?</a>
Johnson experienced several adverse effects, including mouth ulcers, slow wound healing, cholesterol imbalances, and elevated blood sugar levels. Additionally he also experienced an increase in his resting heart rate.
Read More | <a href="https://www.wionews.com/trending/tech-billionaire-bryan-johnson-who-used-his-teen-sons-blood-to-stay-young-launches-new-religion-dont-die-claims-its-how-we-save-human-race-8833433" rel="dofollow">Bryan Johnson, who used son's blood to stay young, launches new 'religion' Don't Die</a>
&ldquo;To those of you laughing at home, I&rsquo;m laughing with you,&rdquo; he said adding, &ldquo;It&rsquo;s important to talk about both the successes and the failures,&rdquo; he said. &ldquo;That&rsquo;s how we all learn.&rdquo; He also informed people that he has stopped taking the drug. He added that he is committed to experimenting, documenting, and, crucially, sharing. &ldquo;It&rsquo;s important to talk about both the successes and the failures,&rdquo; he said. &ldquo;That&rsquo;s how we all learn.&rdquo;
The tech millionaire is known for his extreme anti-ageing methods, involving his son, Talmage (17). He in an unconventional "multigenerational plasma exchange" experiment, injected himself with his son's blood.&nbsp;
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<h2>Bryan Johnson launches "Don't Die" movement</h2>
Bryan Johnson recently launched a new 'religion' to "solve death" and "save" the human race. "Dear humanity, I am building a religion," announced Johnson on X.
<blockquote class="twitter-tweet publive-iframes-block publive-Twitter-block" contenteditable="false" width="600" height="400" id="PL_blockquote_block-m96rr95g-elkb3wmr-nqakrv59">
Dear humanity, I am building a religion. Wait a second, I know what you&rsquo;re going to say. Hold that knee-jerk reaction and let me explain. First, here&rsquo;s what&rsquo;s going to happen: + Don&rsquo;t Die becomes history's fastest-growing ideology. + It saves the human race. + And ushers in&hellip; <a href="https://t.co/MJcrU9uXNf">pic.twitter.com/MJcrU9uXNf</a>
&mdash; Bryan Johnson (@bryan_johnson) <a href="https://twitter.com/bryan_johnson/status/1898062895533195497?ref_src=twsrc%5Etfw">March 7, 2025</a></blockquote>
As Johnson puts it, Don't Die is a "universal translator and the grand unifying theory of existence."&nbsp;He said that with democracy governing civic matters, capitalism dictating wealth and religion caring for the soul, "existing frameworks are too narrow".&nbsp;Instead, he proposes his religion, which he claims "speaks fluently with...+ the universe through physics + AI via mathematics + software via computation + living things via biology + humans via storytelling + truth via memetics".
Read More | <a href="https://www.wionews.com/world/age-reversing-expert-bryan-johnson-says-he-loved-being-in-india-but-is-shocked-by-781489" rel="dofollow">Age-reversing enterpreneur Bryan Johnson says he 'loved being in India', but is 'shocked by...'</a>
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Trending | Billionaire and 'biohacker' Bryan Johnson, "who wants to live forever", has revealed that he may have accidentally sped up his aging process

Billionaire and 'biohacker' Bryan Johnson, "who wants to live forever", has revealed in a new YouTube video that he may have accidentally sped up his aging process rather than slowing it down. Notably, Johnson spends $2 million a year to reverse his biological age. In a new video posted on his YouTube channel, Johnson revealed a significant error concerning rapamycin, a immunosuppressant, popular in anti-aging circles. Johnson modified the dosage after testing and reseraching on rapamycin to manage potential benefits and risks. However, instead of experiencing rejuvenation, the tech entrepreneur began noticing side effects. Read More | What is this 'anti-ageing' drug Bryan Johnson is warning about? Johnson experienced several adverse effects, including mouth ulcers, slow wound healing, cholesterol imbalances, and elevated blood sugar levels. Additionally he also experienced an increase in his resting heart rate. Read More | Bryan Johnson, who used son's blood to stay young, launches new 'religion' Don't Die “To those of you laughing at home, I’m laughing with you,” he said adding, “It’s important to talk about both the successes and the failures,” he said. “That’s how we all learn.” He also informed people that he has stopped taking the drug. He added that he is committed to experimenting, documenting, and, crucially, sharing. “It’s important to talk about both the successes and the failures,” he said. “That’s how we all learn.” The tech millionaire is known for his extreme anti-ageing methods, involving his son, Talmage (17). He in an unconventional "multigenerational plasma exchange" experiment, injected himself with his son's blood. Read More | Bryan Johnson shares his penis age, claims nighttime erections hint at overall health Bryan Johnson launches "Don't Die" movement Bryan Johnson recently launched a new 'religion' to "solve death" and "save" the human race. "Dear humanity, I am building a religion," announced Johnson on X. Dear humanity, I am building a religion. Wait a second, I know what you’re going to say. Hold that knee-jerk reaction and let me explain. First, here’s what’s going to happen: + Don’t Die becomes history's fastest-growing ideology. + It saves the human race. + And ushers in… pic.twitter.com/MJcrU9uXNf — Bryan Johnson (@bryan_johnson) March 7, 2025 As Johnson puts it, Don't Die is a "universal translator and the grand unifying theory of existence." He said that with democracy governing civic matters, capitalism dictating wealth and religion caring for the soul, "existing frameworks are too narrow". Instead, he proposes his religion, which he claims "speaks fluently with...+ the universe through physics + AI via mathematics + software via computation + living things via biology + humans via storytelling + truth via memetics". Read More | Age-reversing enterpreneur Bryan Johnson says he 'loved being in India', but is 'shocked by...'

Bryan Johnson gets a setback on anti-aging experiment, reveals he made himself older

Scientists from Imperial College London may have discovered a way to stop ageing and prevent cancer. A recent research article published in the journal Nature claims that the lifespan of humans could be extended by 25 per cent with this new anti-ageing formula.

The researchers experimented on mice and found out that switching off interleukin-11 (IL-11), a protein, can help prevent cancer, boost metabolism, hearing and vision, and improve lung and muscle function. It may also prevent greying and falling of hair.

According to the tests conducted, the treated mice lived for an average of 155 weeks, while the remaining untreated for 120 weeks.&nbsp;

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“These findings are very exciting," said Stuart Cook, professor at the Medical Research Council Laboratory of Medical Science, Imperial College, reported Telegraph.

“The treated mice had fewer cancers, and were free from the usual signs of ageing and frailty, but we also saw reduced muscle wasting and improvement in muscle strength. In other words, the old mice receiving anti-IL11 (treatment) were healthier," cook further said.

<h2>The new drug may stop ageing in humans</h2>

Although this research was conducted only on mice, the scientists believe that the drug could have a similar response in elderly people.&nbsp;

The IL-11 gene was adapted by humans from fish millions of years back. This gene also helps with the regeneration of limbs in some species. While it was useful in ancient times, it is known to be unnecessary in humans now. It can result in scarring and thickening of tissues and inflammation which causes diseases and ageing.

Also Read |&nbsp;<a href="https://www.wionews.com/science/has-humanity-defeated-ageing-scientists-strike-single-pill-breakthrough-616309">Has humanity defeated ageing? Scientists strike 'single pill' breakthrough</a>

Researchers came up with the theory that suppressing IL-11 may prevent ageing after running tests on animals in the lab when the protein values grew significantly.

<h2>Other anti-ageing breakthroughs</h2>

There are also other studies working to improve the quality of life of humans and delay ageing. One such study conducted by scientists from Harvard Medical School and Massachusetts Institute of Technology has uncovered a pill which can make human cells younger.&nbsp;

This breakthrough can eliminate the necessity for gene therapy to reverse ageing. With a single pill, it can help improve eyesight and treat age-related illnesses.

(WIth inputs from agencies)

Scientists from Imperial College London may have discovered a way to stop ageing and prevent cancer. A recent research article published in the journal Nature claims that the lifespan of humans could be extended by 25 per cent with this new anti-ageing formula.

Scientists from Imperial College London may have discovered a way to stop ageing and prevent cancer. A recent research article published in the journal Nature claims that the lifespan of humans could be extended by 25 per cent with this new anti-ageing formula. The researchers experimented on mice and found out that switching off interleukin-11 (IL-11), a protein, can help prevent cancer, boost metabolism, hearing and vision, and improve lung and muscle function. It may also prevent greying and falling of hair. According to the tests conducted, the treated mice lived for an average of 155 weeks, while the remaining untreated for 120 weeks. Also Read | Scientists now have an antidote for killer cobra venom. It's common blood thinner! “These findings are very exciting," said Stuart Cook, professor at the Medical Research Council Laboratory of Medical Science, Imperial College, reported Telegraph. “The treated mice had fewer cancers, and were free from the usual signs of ageing and frailty, but we also saw reduced muscle wasting and improvement in muscle strength. In other words, the old mice receiving anti-IL11 (treatment) were healthier," cook further said. The new drug may stop ageing in humans Although this research was conducted only on mice, the scientists believe that the drug could have a similar response in elderly people. The IL-11 gene was adapted by humans from fish millions of years back. This gene also helps with the regeneration of limbs in some species. While it was useful in ancient times, it is known to be unnecessary in humans now. It can result in scarring and thickening of tissues and inflammation which causes diseases and ageing. Also Read | Has humanity defeated ageing? Scientists strike 'single pill' breakthrough Researchers came up with the theory that suppressing IL-11 may prevent ageing after running tests on animals in the lab when the protein values grew significantly. Other anti-ageing breakthroughs There are also other studies working to improve the quality of life of humans and delay ageing. One such study conducted by scientists from Harvard Medical School and Massachusetts Institute of Technology has uncovered a pill which can make human cells younger. This breakthrough can eliminate the necessity for gene therapy to reverse ageing. With a single pill, it can help improve eyesight and treat age-related illnesses. (WIth inputs from agencies)

Scientists discover anti-ageing formula which can also stop cancer

Greenland sharks live up to a whopping 400 years and even more without showing traditional signs of ageing. Their hearts also remain healthy and a typical Greenland shark is not afflicted by any serious cardiovascular disease. Whatever their secret is, it can also help humans stay young and healthy, scientists believe.&nbsp;

The world's longest-living vertebrates have defied age and scientists have been trying to understand the biological mechanisms that keep them healthy. The belief is that learning about the sharks' anti-ageing ways&nbsp;can also help human beings stay healthier. The main reason seems to be their metabolic activity.

The Greenland sharks live in the freezing waters of the North Atlantic and Antarctic oceans where their extremely slow metabolisms are what help&nbsp;them survive. Other metabolic adaptations seen in these sharks are that their top swimming speed is less than 1.8 miles per hour, and they grow less than 0.4 inches a year. These adaptations might be the reason why these fishes live for several years without showing any signs of ageing.&nbsp;

Also Read:&nbsp;<a href="https://www.wionews.com/science/earth-moves-to-farthest-point-from-sun-but-dont-expect-any-relief-from-the-heat-738099">Earth moves to farthest point from sun, but don't expect any relief from the heat</a> 
&nbsp;

<h2>No signs of ageing seen in&nbsp;Greenland sharks</h2>

As we age, changes in enzymatic activity are bound to happen. But these changes have not been seen in Greenland sharks. Enzymes are integral to the chemical reactions that happen within our cells. Ewan Camplisson, a Ph.D. student at the University of Manchester, says that the enzymes from the muscles of Greenland sharks don’t show the kinds of activity that you’d anticipate through ageing.

Camplisson told Newsweek that traditional sign of ageing are missing from these sharks but are seen in most animals. So the researchers are now wondering whether metabolism is the reason for their long life span. By learning how they live so long while keeping their hearts healthy, Camplisson hopes to improve the quality of life of humans, especially older people, who suffer from heart issues more than others.&nbsp;

Talking about a healthy heart, Camplisson said,&nbsp;"If we can understand what adaptations allow the Greenland sharks to live so long while seemingly not being seriously afflicted by cardiovascular disease, we can hopefully incorporate some of these adaptations into humans to allow improved cardiac health."

Greenland sharks live up to a whopping 400 years and even more without showing traditional signs of ageing. Their hearts also remain healthy and a typical Greenland shark is not afflicted by any serious cardiovascular disease.

Greenland sharks live up to a whopping 400 years and even more without showing traditional signs of ageing. Their hearts also remain healthy and a typical Greenland shark is not afflicted by any serious cardiovascular disease. Whatever their secret is, it can also help humans stay young and healthy, scientists believe. The world's longest-living vertebrates have defied age and scientists have been trying to understand the biological mechanisms that keep them healthy. The belief is that learning about the sharks' anti-ageing ways can also help human beings stay healthier. The main reason seems to be their metabolic activity. The Greenland sharks live in the freezing waters of the North Atlantic and Antarctic oceans where their extremely slow metabolisms are what help them survive. Other metabolic adaptations seen in these sharks are that their top swimming speed is less than 1.8 miles per hour, and they grow less than 0.4 inches a year. These adaptations might be the reason why these fishes live for several years without showing any signs of ageing. Also Read: Earth moves to farthest point from sun, but don't expect any relief from the heat No signs of ageing seen in Greenland sharks As we age, changes in enzymatic activity are bound to happen. But these changes have not been seen in Greenland sharks. Enzymes are integral to the chemical reactions that happen within our cells. Ewan Camplisson, a Ph.D. student at the University of Manchester, says that the enzymes from the muscles of Greenland sharks don’t show the kinds of activity that you’d anticipate through ageing. Camplisson told Newsweek that traditional sign of ageing are missing from these sharks but are seen in most animals. So the researchers are now wondering whether metabolism is the reason for their long life span. By learning how they live so long while keeping their hearts healthy, Camplisson hopes to improve the quality of life of humans, especially older people, who suffer from heart issues more than others. Talking about a healthy heart, Camplisson said, "If we can understand what adaptations allow the Greenland sharks to live so long while seemingly not being seriously afflicted by cardiovascular disease, we can hopefully incorporate some of these adaptations into humans to allow improved cardiac health."

Sharks hold the secret to a healthy heart and staying young, study finds

Retired naval officer Joseph Dituri&nbsp;was asked&nbsp;to stay underwater for over three months as a requirement for a path-breaking study. Scientists wanted to know the effects of living underwater in a pressurised environment on the human body. And guess what, scientists&nbsp;were shocked to learn that Dituri had turned '10 years younger' when he stepped out of his compact&nbsp;pod,&nbsp;after&nbsp;having stayed&nbsp;over three months in the depths of the Atlantic Ocean.

<h2>What changes&nbsp;were noticed?</h2>

After medical assessments,&nbsp;it was revealed&nbsp;that Dituri's&nbsp;telomeres, the DNA caps at the ends of chromosomes&nbsp;that typically shrink with age, became 20 per cent longer than three months earlier.

Apart from that, his stem cell count had also gone up, with his overall health witnessing a remarkable transformation.

Also read:&nbsp;<a data-ved="2ahUKEwjr2dft_pmGAxX6TmwGHeFcCgUQxfQBKAB6BAgMEAE" href="https://www.wionews.com/world/yemens-houthis-claim-to-have-targeted-us-warship-and-vessel-destiny-in-red-sea-721810" jsname="YKoRaf" ping="/url?sa=t&amp;source=web&amp;rct=j&amp;opi=89978449&amp;url=https://www.wionews.com/world/yemens-houthis-claim-to-have-targeted-us-warship-and-vessel-destiny-in-red-sea-721810&amp;ved=2ahUKEwjr2dft_pmGAxX6TmwGHeFcCgUQxfQBKAB6BAgMEAE">Yemen’s Houthis claim to have targeted US warship and vessel ‘Destiny’ in Red Sea</a>

Dituri also experienced an enhanced sleep quality. His cholesterol levels dropped by 72 points, and&nbsp;his inflammatory markers were cut&nbsp;in half. Doctors said these changes occurred due to the underwater pressure, which is known to have many beneficial effects on the body.

Dituri later spoke about why people needed such experiences.

"You need one of these places that is cut off from outside activity. Send people down here for a two-week vacation, where they get their feet scrubbed, relax and can experience the benefit of hyperbaric medicine," he was quoted as saying by Daily Mirror, a British tabloid.

Also read:&nbsp;<a data-ved="2ahUKEwjr2dft_pmGAxX6TmwGHeFcCgUQxfQBKAB6BAgPEAE" href="https://www.wionews.com/videos/south-china-sea-tensions-india-malaysia-back-philippines-hold-naval-drills-with-china-in-mind-722681" jsname="YKoRaf" ping="/url?sa=t&amp;source=web&amp;rct=j&amp;opi=89978449&amp;url=https://www.wionews.com/videos/south-china-sea-tensions-india-malaysia-back-philippines-hold-naval-drills-with-china-in-mind-722681&amp;ved=2ahUKEwjr2dft_pmGAxX6TmwGHeFcCgUQxfQBKAB6BAgPEAE">South China Sea Tensions: India, Malaysia back Philippines - hold naval drills with China in mind</a>

He said that he also experienced&nbsp;major&nbsp;improvements in his metabolism.&nbsp;

During his time underwater, he said he would work out for over an hour, five days a week, using only his exercise bands.

Joseph Dituri achieved another major feat during his 93-day endeavour. He shattered the previous world record for underwater habitation, which was 73 days.

(With inputs from agencies)

Retired naval officer Joseph Dituri was asked to stay underwater for over three months as a requirement for a path-breaking study. Scientists wanted to know the effects of living underwater in a pressurised environment on the human body.

Retired naval officer Joseph Dituri was asked to stay underwater for over three months as a requirement for a path-breaking study. Scientists wanted to know the effects of living underwater in a pressurised environment on the human body. And guess what, scientists were shocked to learn that Dituri had turned '10 years younger' when he stepped out of his compact pod, after having stayed over three months in the depths of the Atlantic Ocean. What changes were noticed? After medical assessments, it was revealed that Dituri's telomeres, the DNA caps at the ends of chromosomes that typically shrink with age, became 20 per cent longer than three months earlier. Apart from that, his stem cell count had also gone up, with his overall health witnessing a remarkable transformation. Also read: Yemen’s Houthis claim to have targeted US warship and vessel ‘Destiny’ in Red Sea Dituri also experienced an enhanced sleep quality. His cholesterol levels dropped by 72 points, and his inflammatory markers were cut in half. Doctors said these changes occurred due to the underwater pressure, which is known to have many beneficial effects on the body. Dituri later spoke about why people needed such experiences. "You need one of these places that is cut off from outside activity. Send people down here for a two-week vacation, where they get their feet scrubbed, relax and can experience the benefit of hyperbaric medicine," he was quoted as saying by Daily Mirror, a British tabloid. Also read: South China Sea Tensions: India, Malaysia back Philippines - hold naval drills with China in mind He said that he also experienced major improvements in his metabolism. During his time underwater, he said he would work out for over an hour, five days a week, using only his exercise bands. Joseph Dituri achieved another major feat during his 93-day endeavour. He shattered the previous world record for underwater habitation, which was 73 days. (With inputs from agencies)

Man spends 93 days under Atlantic Sea, becomes ‘10 years younger’

Chinese scientists claim to have discovered an anti-ageing component in the blood of young mice, with the longest surviving mouse in their research living for up to 1,266 days which are almost 120-130 years in human age.

According to a peer-reviewed study published in the journal Nature Ageing, male mice aged 20 months, with a median lifetime of 840 days, received weekly injections of the blood component. The researchers reported a 22.7 per cent rise to a median of 1,031 days.

The injections also significantly reduced age-related functional deterioration in old mice, according to Zhang Chenyu, co-leader of the study.

Zhang claimed that public fears about other ethical issues, such as the possibility that young people's blood will be used immorally, were "exaggerated misconceptions." He stated that if the treatment is ever established, it will be given via medications and not via direct plasma exchange. This knowledge can help the development of simplified and targeted treatments.

According to corresponding author Chen Xi, who is also from Nanjing University, "what we are doing is showing at the cellular level what is actually working in the blood, what are the most potent rejuvenating factors."

According to the Chinese team, previous study has mostly focussed on the possible anti-aging capabilities of soluble protein components found in youthful blood.

Also read:&nbsp;<meta name="uuid" content="uuideh9WpNBTnM51" /><a href="http://wionews.com/science/accelerated-aging-heightens-cancer-risk-in-younger-population-study-709980" target="_blank">Accelerated ageing is heightening cancer risk in younger population: Study</a>

The study lasted seven years and involved data collecting from hundreds of mice. According to the researchers, small extracellular vesicles (sEVs), which are actively released by virtually all cell types and found in many bodily fluids, including blood, played an important role in correcting age-related degenerative alterations in older mice.

It is commonly established that sEVs transport nucleic acids and proteins across cells, hence enabling information transmission. The scientists reported that by recognising and using this process, they were able to observe greater survival periods than in previous studies on animals.

"[The 22.7 per cent increase in lifespan] is one of the longest records in the world," Chen said,&nbsp;adding that the mice in the most recent study were reasonably active at the end of their lives.

Chen stated that the research was only the beginning, with many scientific issues still to be solved before the discoveries can be clinically evaluated and developed into a medicine. Before any prospective cure is developed, trials must be conducted in large primates that are more similar to humans, he added. 
 
(With inputs from agencies)

Chinese scientists claim to have discovered an anti-ageing component in the blood of young mice, with the longest surviving mouse in their research living for up to 1,266 days which are almost 120-130 years in human age.

Chinese scientists claim to have discovered an anti-ageing component in the blood of young mice, with the longest surviving mouse in their research living for up to 1,266 days which are almost 120-130 years in human age. According to a peer-reviewed study published in the journal Nature Ageing, male mice aged 20 months, with a median lifetime of 840 days, received weekly injections of the blood component. The researchers reported a 22.7 per cent rise to a median of 1,031 days. The injections also significantly reduced age-related functional deterioration in old mice, according to Zhang Chenyu, co-leader of the study. Zhang claimed that public fears about other ethical issues, such as the possibility that young people's blood will be used immorally, were "exaggerated misconceptions." He stated that if the treatment is ever established, it will be given via medications and not via direct plasma exchange. This knowledge can help the development of simplified and targeted treatments. According to corresponding author Chen Xi, who is also from Nanjing University, "what we are doing is showing at the cellular level what is actually working in the blood, what are the most potent rejuvenating factors." According to the Chinese team, previous study has mostly focussed on the possible anti-aging capabilities of soluble protein components found in youthful blood. Also read: Accelerated ageing is heightening cancer risk in younger population: Study The study lasted seven years and involved data collecting from hundreds of mice. According to the researchers, small extracellular vesicles (sEVs), which are actively released by virtually all cell types and found in many bodily fluids, including blood, played an important role in correcting age-related degenerative alterations in older mice. It is commonly established that sEVs transport nucleic acids and proteins across cells, hence enabling information transmission. The scientists reported that by recognising and using this process, they were able to observe greater survival periods than in previous studies on animals. "[The 22.7 per cent increase in lifespan] is one of the longest records in the world," Chen said, adding that the mice in the most recent study were reasonably active at the end of their lives. Chen stated that the research was only the beginning, with many scientific issues still to be solved before the discoveries can be clinically evaluated and developed into a medicine. Before any prospective cure is developed, trials must be conducted in large primates that are more similar to humans, he added. (With inputs from agencies)

Chinese scientists find 'fountain of youth' in blood of young that can extend life up to 130 years

This new anti-ageing therapy can rewind age related changes in the body. Powerful hydrogen therapy can rewind age and age related diseases.

Chinese scientists develop therapy to reverse ageing

anti-ageing-0

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