A small plane crashed in a densely populated San Diego suburb, killing at least two people and injuring two, leaving a trail of destruction. There were no signs of the plane remains from the aerial footage.

San Diego: Plane crashes into residential area, killing at least two people

US Coast Guard offloads 11,500 pounds of seized cocaine worth $220 million in San Diego

San Diego comic-con will be virtual for 2021

Woman make up under 10% in the work force in US construction industry. But, there is this San Diego woman who seeks to break the industries 'glass ceiling'. Watch the report

San Diego woman seeking to break into construction industry

An endangered ring-tailed lemur has given birth to twins at the San Diego Zoo. Veterinarians have checked the two little lemurs and a wildlife care specialist says their mother, Rosalita, is performing all the appropriate behaviors for a mother lemur.

Twin ring-tailed lemurs born at San Diego Zoo

Forced to cancel her 104th birthday celebrations due to the coronavirus outbreak, Ruth Gallivan's neighbors and friends in San Diego decided to bring the party to her by holding a surprise, drive-by, birthday party outside the centenarian's house.

Drive-by birthday party for 104-year-old WWII veteran in San Diego

Longest smuggling tunnel discovered under US-Mexico Border; possible connections to Sinaloa cartel

Mysteries of the deep: How some sharks glow green in the dark

United States psychoanalysts apologise for labeling homosexuality an illness

Starting on Tuesday morning, letters and packages moving between Phoenix and Dallas will travel on customized Peterbilt trucks run by TuSimple, an autonomous startup based in San Diego. There will be five round trips between the two cites, with the first haul leaving from Phoenix this morning. It’s the first time that the Postal Service has contracted with an autonomous provider for long-haul service.

WION Wallet: USPS Is Testing Self-Driving Trucks to Move Mail and Packages Between Cities

Blind Japanese sailor completes non-stop Pacific voyage

US delays returning asylum seekers to Mexico

Police said 39-year-old Nasim Najafi Aghdam from San Diego was behind Tuesday's shooting at YouTube's offices in Silicon Valley

Watch: YouTube attacker was vegan activist, accused tech firm of discrimination

The trip to California-- the most populous in the country and a Democratic stronghold -- was largely upstaged by his own announcement that he had sacked Secretary of State Rex Tillerson

Trump, in California, warns of 'bedlam' without border wall

'My new national strategy for space recognizes that space is a war-fighting domain, just like the land, air, and sea,' Trump said

Trump pushes for new 'space force'

About 200,000 residents were evacuated from their homes at one point, though some were due to return on Thursday evening

Be 'ready to GO!' Southern California warns residents as fires rage

The models, which cost the government up to $500,000 each, were spaced 30 feet (9.1 meters) apart

Trump's border wall models take shape in San Diego

Police claim to have one suspect in custody, and continue the search for more

Two police officers shot in San Diego

It has led to the evacuation of hundreds of residents from ranches and campgrounds in the area close to Santa Barbara

Firefighters hold 'sleeping giant' wildfire in check in California,

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