A study reveals that nearly half of dementia cases could be prevented or delayed by addressing 14 key risk factors, starting from childhood. This discovery offers hope in the global fight against a condition that affects millions of people worldwide

<h2>What is dementia?</h2>

Dementia is a condition that affects memory, thinking, problem-solving, language and other cognitive abilities, interfering with daily life and activities. Rather than being a specific disease, dementia is a collection of symptoms caused by various underlying conditions. There are several different forms of dementia, including Alzheimer’s disease, which is the most common. Individuals may also exhibit changes in mood and behaviour, struggle with organising tasks and experience disorientation. As the condition advances, managing daily activities becomes increasingly difficult, affecting overall quality of life.

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<h2>New risk factors identified for dementia</h2>

World-leading experts have discovered two new risk factors for dementia: high cholesterol and vision loss. These factors are responsible for nearly one in ten dementia cases globally. The newly identified risks add to the 12 known factors that increase the likelihood of developing dementia. These factors include genetics, smoking status and other health conditions.

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<h2>Global impact of dementia</h2>

Dementia affects more than 55 million people worldwide. It is caused by various diseases, with Alzheimer's being the most common. A recent review in The Lancet journal underscores the high potential for preventing dementia. The study follows a previous report from 2020 that also emphasised the importance of prevention in combating this condition.

<h2>EU Rejects New Dementia Drug</h2>

The EU's medicine watchdog recently declined to approve lecanemab and is still reviewing donanemab. These Alzheimer's treatments, approved in the US last year and developed by Biogen and Eli Lilly, target the proteins tau and amyloid beta, which are central to disease progression. However, they come with severe side effects and high costs.

Despite decades of research and significant investment, a cure for dementia remains elusive. Some researchers hope these drugs will lead to more effective treatments in the future, while others emphasise the importance of prevention strategies for dementia.

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(With inputs from agencies)

A study reveals that nearly half of dementia cases could be prevented or delayed by addressing 14 key risk factors, starting from childhood. This discovery offers hope in the global fight against a condition that affects millions of people worldwide What is dementia?

A study reveals that nearly half of dementia cases could be prevented or delayed by addressing 14 key risk factors, starting from childhood. This discovery offers hope in the global fight against a condition that affects millions of people worldwide What is dementia? Dementia is a condition that affects memory, thinking, problem-solving, language and other cognitive abilities, interfering with daily life and activities. Rather than being a specific disease, dementia is a collection of symptoms caused by various underlying conditions. There are several different forms of dementia, including Alzheimer’s disease, which is the most common. Individuals may also exhibit changes in mood and behaviour, struggle with organising tasks and experience disorientation. As the condition advances, managing daily activities becomes increasingly difficult, affecting overall quality of life. Also read | Russian spies' children discovered their nationality during flight to Moscow: Kremlin New risk factors identified for dementia World-leading experts have discovered two new risk factors for dementia: high cholesterol and vision loss. These factors are responsible for nearly one in ten dementia cases globally. The newly identified risks add to the 12 known factors that increase the likelihood of developing dementia. These factors include genetics, smoking status and other health conditions. Also read | AI tool predicts Alzheimer's disease onset better than clinical trials. Here is how it works Global impact of dementia Dementia affects more than 55 million people worldwide. It is caused by various diseases, with Alzheimer's being the most common. A recent review in The Lancet journal underscores the high potential for preventing dementia. The study follows a previous report from 2020 that also emphasised the importance of prevention in combating this condition. EU Rejects New Dementia Drug The EU's medicine watchdog recently declined to approve lecanemab and is still reviewing donanemab. These Alzheimer's treatments, approved in the US last year and developed by Biogen and Eli Lilly, target the proteins tau and amyloid beta, which are central to disease progression. However, they come with severe side effects and high costs. Despite decades of research and significant investment, a cure for dementia remains elusive. Some researchers hope these drugs will lead to more effective treatments in the future, while others emphasise the importance of prevention strategies for dementia. Also read | World's first immunotherapy for peanut allergy in babies starts in Australia (With inputs from agencies)

Tackling 14 risk factors could prevent or delay nearly half of dementia cases, study reveals

A study published in The Lancet Infectious Diseases, released on Friday, based on data from 185 countries and territories collected from December 8, 2020, to December 8, 2021, shows that Covid vaccines prevented nearly 20 million deaths in the first year after they were introduced, as reported by AFP.

It is the first attempt to estimate the number of deaths prevented directly and indirectly as a result of Covid-19 vaccinations. It found that 19.8 million deaths were prevented out of a potential 31.4 million deaths that would have occurred if no vaccines were available.

It was a 63 per cent reduction, the study found. &nbsp;The study used official figures or estimates when official data was not available for deaths from Covid, as well as total excess deaths from each country. These analyses were compared with a hypothetical alternative scenario in which no vaccine was administered.&nbsp;

The model accounted for variation in vaccination rates across countries, as well as differences in vaccine effectiveness based on the types of vaccines known to have been primarily used in each country. &nbsp;

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The study found that high- and middle-income countries accounted for the largest number of deaths averted, 12.2 million out of 19.8 million, reflecting inequalities in access to vaccines worldwide.&nbsp;

Covid has officially killed more than 6.3 million people globally, according to the WHO. Nearly 600,000 additional deaths could have been prevented if the World Health Organization's (WHO) goal of vaccinating 40 per cent of each country's population by the end of 2021 had been met, it concluded. &nbsp;

As reported by AFP, lead study author Oliver Watson of Imperial College London said, "Millions of lives have probably been saved by making vaccines available to people around the world."

"We could have done more," he said. &nbsp;

( with inputs from agencies)

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A study published in The Lancet Infectious Diseases, released on Friday, based on data from 185 countries and territories collected from December 8, 2020, to December 8, 2021, shows that Covid vaccines prevented nearly 20 million deaths in the first year after they were introduced, as reported by AFP.

A study published in The Lancet Infectious Diseases, released on Friday, based on data from 185 countries and territories collected from December 8, 2020, to December 8, 2021, shows that Covid vaccines prevented nearly 20 million deaths in the first year after they were introduced, as reported by AFP. It is the first attempt to estimate the number of deaths prevented directly and indirectly as a result of Covid-19 vaccinations. It found that 19.8 million deaths were prevented out of a potential 31.4 million deaths that would have occurred if no vaccines were available. It was a 63 per cent reduction, the study found. The study used official figures or estimates when official data was not available for deaths from Covid, as well as total excess deaths from each country. These analyses were compared with a hypothetical alternative scenario in which no vaccine was administered. The model accounted for variation in vaccination rates across countries, as well as differences in vaccine effectiveness based on the types of vaccines known to have been primarily used in each country. Also Read: J&K to host G20 meetings in 2023, first major international summit after abrogation of Article 370 The study found that high- and middle-income countries accounted for the largest number of deaths averted, 12.2 million out of 19.8 million, reflecting inequalities in access to vaccines worldwide. Covid has officially killed more than 6.3 million people globally, according to the WHO. Nearly 600,000 additional deaths could have been prevented if the World Health Organization's (WHO) goal of vaccinating 40 per cent of each country's population by the end of 2021 had been met, it concluded. As reported by AFP, lead study author Oliver Watson of Imperial College London said, "Millions of lives have probably been saved by making vaccines available to people around the world." "We could have done more," he said. ( with inputs from agencies) WATCH WION LIVE HERE You can now write for wionews.com and be a part of the community. Share your stories and opinions with us here.

Covid vaccines prevented nearly 20 million deaths in first year: Report

Vaccination is highly effective at preventing severe cases of COVID-19, even against the Delta variant, a vast study in France has shown.

The research published Monday -- focusing on prevention of severe Covid and death, not infection -- looked at 22 million people over 50 and found those who had received jabs were 90 percent less likely to be hospitalised or die.

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The results confirm observations from the US, the UK and Israel, but researchers say it is the largest study of its kind so far.

Looking at data collected starting in December 2020, when France launched its jab campaign, the researchers compared the outcomes of 11 million vaccinated people with 11 million unvaccinated subjects.

They formed pairs matching an unvaccinated individual with a vaccinated counterpart from the same region and of the same age and sex, tracking them from the date of the vaccinated person's second jab to July 20.

Starting 14 days after a second dose, a vaccinated subjects' risk of severe Covid was reduced by 90 percent, according to the research conducted by Epi-Phare, an independent medicines safety research group that works closes with the French government.

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Vaccination appears to be nearly as effective against for the Delta variant, with 84 percent protection for people 75 and older and 92 percent for people 50-75.

That estimate, however, is only based on a month of data, since the variant became dominant in France only in June.

"The study should be followed up to include results from August and September," epidemiologist Mahmoud Zureik, the head of Epi-Phare, told AFP.

The study covers vaccination with the Pfizer/BioNtech, Moderna and AstraZeneca jabs, but not Jannsen which was authorised much later and is far less widely used in France.

The results also suggest that over the period of study -- up to five months -- vaccination protection against severe Covid did not diminish.

Vaccination is highly effective at preventing severe cases of COVID-19, even against the Delta variant, a vast study in France has shown. The research published Monday -- focusing on prevention of severe Covid and death, not infection -- looked at 22 million people over 50 and found those who had received jabs were 90 percent less likely to be hospitalised or die.

Vaccination is highly effective at preventing severe cases of COVID-19, even against the Delta variant, a vast study in France has shown. The research published Monday -- focusing on prevention of severe Covid and death, not infection -- looked at 22 million people over 50 and found those who had received jabs were 90 percent less likely to be hospitalised or die. Also Read | 'Blood, sweat, no beers': Sydney set to ease key COVID-19 curbs The results confirm observations from the US, the UK and Israel, but researchers say it is the largest study of its kind so far. Looking at data collected starting in December 2020, when France launched its jab campaign, the researchers compared the outcomes of 11 million vaccinated people with 11 million unvaccinated subjects. They formed pairs matching an unvaccinated individual with a vaccinated counterpart from the same region and of the same age and sex, tracking them from the date of the vaccinated person's second jab to July 20. Starting 14 days after a second dose, a vaccinated subjects' risk of severe Covid was reduced by 90 percent, according to the research conducted by Epi-Phare, an independent medicines safety research group that works closes with the French government. Also Read | No quarantine for fully vaccinated Indians in UK from October 11: British envoy Vaccination appears to be nearly as effective against for the Delta variant, with 84 percent protection for people 75 and older and 92 percent for people 50-75. That estimate, however, is only based on a month of data, since the variant became dominant in France only in June. "The study should be followed up to include results from August and September," epidemiologist Mahmoud Zureik, the head of Epi-Phare, told AFP. The study covers vaccination with the Pfizer/BioNtech, Moderna and AstraZeneca jabs, but not Jannsen which was authorised much later and is far less widely used in France. The results also suggest that over the period of study -- up to five months -- vaccination protection against severe Covid did not diminish.

Vaccines prevent severe Covid, even from Delta: study

Powerful business lobbying bodies on Thursday sued the Obama administration, seeking to strike down recent rules intended to prevent corporate tax avoidance through so-called inversions. 
 
In a rule adopted in April, the US Treasury sought to prevent American companies from moving overseas to reduce their tax burdens, often through reverse mergers. The pharmaceutical giant Pfizer that month abandoned plans for a merger with Botox producer Allergan, based in Ireland, as a result. 
 
In a complaint filed in US District Court in Texas, the US Chamber of Commerce and the Texas Association of Business accused the Obama administration of attempting to re-write US tax laws while bypassing the legislature, which is controlled by Republicans and hostile to the measure. If the rule is allowed to stand, &quot;it is not just mergers that will suffer, it is the rule of law, and the certainty and stability required for effective commerce,&quot; the complaint said. 
 
In a statement, US Chamber President, Tom Donahue, said the Treasury and Internal Revenue Service had &quot;ignored the clear limits of a statute, and simply rewrote the law unilaterally.&quot; 
 
The Treasury Department said on Thursday it had acted within its powers to address what lawmakers had failed to. 
 
&quot;In the absence of congressional action, Treasury proposed regulations to eliminate tax benefits for companies that acquire multiple US firms over a short period of time,&quot; the department said. 
 
&quot;This action was based on strong policy interests and clear legal authority. We will continue to defend these regulations, which will help slow the erosion of our corporate tax base.&quot; 
 
According to the rule adopted in April, companies formed in tax inversions can be subject to higher taxes if the newly formed company does less than 25 per cent of its business in the foreign country where it is incorporated, or if the shareholders in the old American parent company end up owning at least 60 per cent of the new foreign parent. 
 
(AFP)

The US Treasury, in a rule adopted in April, has sought to prevent American companies from moving overseas to reduce tax burden

Powerful business lobbying bodies on Thursday sued the Obama administration, seeking to strike down recent rules intended to prevent corporate tax avoidance through so-called inversions. In a rule adopted in April, the US Treasury sought to prevent American companies from moving overseas to reduce their tax burdens, often through reverse mergers. The pharmaceutical giant Pfizer that month abandoned plans for a merger with Botox producer Allergan, based in Ireland, as a result. In a complaint filed in US District Court in Texas, the US Chamber of Commerce and the Texas Association of Business accused the Obama administration of attempting to re-write US tax laws while bypassing the legislature, which is controlled by Republicans and hostile to the measure. If the rule is allowed to stand, "it is not just mergers that will suffer, it is the rule of law, and the certainty and stability required for effective commerce," the complaint said. In a statement, US Chamber President, Tom Donahue, said the Treasury and Internal Revenue Service had "ignored the clear limits of a statute, and simply rewrote the law unilaterally." The Treasury Department said on Thursday it had acted within its powers to address what lawmakers had failed to. "In the absence of congressional action, Treasury proposed regulations to eliminate tax benefits for companies that acquire multiple US firms over a short period of time," the department said. "This action was based on strong policy interests and clear legal authority. We will continue to defend these regulations, which will help slow the erosion of our corporate tax base." According to the rule adopted in April, companies formed in tax inversions can be subject to higher taxes if the newly formed company does less than 25 per cent of its business in the foreign country where it is incorporated, or if the shareholders in the old American parent company end up owning at least 60 per cent of the new foreign parent. (AFP)

US Big Business sues Obama administration over corporate tax rules

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