<p>A new breakthrough blood test has been invented by scientists for detecting brain cancer. This test churns faster results and is less invasive in comparison to a surgical biopsy.&nbsp;</p>

<p>More than 100 microlitres of blood are required to carry out this novel 'liquid biopsy' and in an hour the method is able to detect biomarkers related to glioblastoma, which is the deadliest brain tumour.&nbsp;</p>

<p>The accuracy of this test is best in comparison to all other existent markers and tests for glioblastoma. According to the prototype's developers, the test has "near turn-key functionality".</p>

<p>A team of scientists from the United States and Australia made the breakthrough and the University of Notre Dame's scientists led the entire team.&nbsp;</p>

<p>The test has been based on sensing mutated blood biomarkers which are known as epidermal growth factor receptors (EGFRs) and are overexpressed in a few kinds of cancers, like&nbsp;glioblastoma.</p>

<p><strong>Also Read:</strong>&nbsp;<a href="https://www.wionews.com/entertainment/lifestyle/news-can-vaccines-prevent-cancer-worlds-first-lung-cancer-vaccine-trials-will-have-answers-752708">Can vaccines prevent cancer? World's first lung cancer vaccine trials will have answers</a></p>

<p>The scientists found these blood biomarkers present inside extracellular vesicles which are small packages filled with proteins, lipids, and genetic material which belong to their original cells.</p>

<p>"Extracellular vesicles or exosomes are unique nanoparticles secreted by cells,"&nbsp;said biomolecular engineer Hsueh-Chia Chang from Notre Dame.</p>

<p>"They are big – 10 to 50 times bigger than a molecule – and they have a weak charge. Our technology was specifically designed for these nanoparticles, using their features to our advantage," he added.</p>

<p>A supersensitive biochip was covered with an untreated sample of blood plasma by the researchers to detect the molecules which were released by cancerous tumour cells.</p>

<p>This chip has a tiny sensor which contains antibodies&nbsp;that get attracted to the exosomes carrying mutated EGFRs.</p>

<p>Once these EGFRs get attached to the biochip, a voltage change happens in the plasma solution which if leads to the creation of a high negative charge, indicates the presence of cancer.&nbsp;</p>

<h2><strong>How do scientists carry out the test to detect cancer in one hour?</strong></h2>

<p>In the experiments done, the clinical blood samples were taken from 10 healthy individuals and 20 patients suffering from glioblastoma and the biochip was tested using them.&nbsp;</p>

<p>For every test, one chip was used. The liquid biopsy was finally able to detect the cancer biomarkers with accuracy and also reflected a very low prognostic value, which hinted that the test is highly replicable.</p>

<p>"Our electrokinetic sensor allows us to do things other diagnostics cannot,"&nbsp;said biomolecular engineer Satyajyoti Senapati from Notre Dame.</p>

<p><strong>Watch:&nbsp;Weight-loss drug Ozempic reveals new benefits like slowing down ageing process</strong></p>

<div class="videoWrapper trancodeVideo"><iframe allowfullscreen="" autoplay="1" class="includeVideo" frameborder="0" height="350" src="https://www.wionews.com/videos/weight-loss-drug-ozempic-reveals-new-benefits-like-slowing-down-ageing-process-754920/embed" style="width:100%;max-width:560px;" width="560"></iframe></div>

<p>"We can directly load blood without any pretreatment to isolate the extracellular vesicles because our sensor is not affected by other particles or molecules. It shows low noise and makes ours more sensitive for disease detection than other technologies," he added.&nbsp;</p>

<p>According to the experts, the biochip was able to accurately detect and quantify exosome concentrations when they were as low as 0.01 per cent.</p>

<p><em>(With inputs from agencies)</em></p>


A new breakthrough blood test has been invented by scientists for detecting brain cancer. This test churns faster results and is less invasive in comparison to a surgical biopsy.

A new breakthrough blood test has been invented by scientists for detecting brain cancer. This test churns faster results and is less invasive in comparison to a surgical biopsy. More than 100 microlitres of blood are required to carry out this novel 'liquid biopsy' and in an hour the method is able to detect biomarkers related to glioblastoma, which is the deadliest brain tumour. The accuracy of this test is best in comparison to all other existent markers and tests for glioblastoma. According to the prototype's developers, the test has "near turn-key functionality". A team of scientists from the United States and Australia made the breakthrough and the University of Notre Dame's scientists led the entire team. The test has been based on sensing mutated blood biomarkers which are known as epidermal growth factor receptors (EGFRs) and are overexpressed in a few kinds of cancers, like glioblastoma. Also Read: Can vaccines prevent cancer? World's first lung cancer vaccine trials will have answers The scientists found these blood biomarkers present inside extracellular vesicles which are small packages filled with proteins, lipids, and genetic material which belong to their original cells. "Extracellular vesicles or exosomes are unique nanoparticles secreted by cells," said biomolecular engineer Hsueh-Chia Chang from Notre Dame. "They are big – 10 to 50 times bigger than a molecule – and they have a weak charge. Our technology was specifically designed for these nanoparticles, using their features to our advantage," he added. A supersensitive biochip was covered with an untreated sample of blood plasma by the researchers to detect the molecules which were released by cancerous tumour cells. This chip has a tiny sensor which contains antibodies that get attracted to the exosomes carrying mutated EGFRs. Once these EGFRs get attached to the biochip, a voltage change happens in the plasma solution which if leads to the creation of a high negative charge, indicates the presence of cancer. How do scientists carry out the test to detect cancer in one hour? In the experiments done, the clinical blood samples were taken from 10 healthy individuals and 20 patients suffering from glioblastoma and the biochip was tested using them. For every test, one chip was used. The liquid biopsy was finally able to detect the cancer biomarkers with accuracy and also reflected a very low prognostic value, which hinted that the test is highly replicable. "Our electrokinetic sensor allows us to do things other diagnostics cannot," said biomolecular engineer Satyajyoti Senapati from Notre Dame. Watch: Weight-loss drug Ozempic reveals new benefits like slowing down ageing process "We can directly load blood without any pretreatment to isolate the extracellular vesicles because our sensor is not affected by other particles or molecules. It shows low noise and makes ours more sensitive for disease detection than other technologies," he added. According to the experts, the biochip was able to accurately detect and quantify exosome concentrations when they were as low as 0.01 per cent. (With inputs from agencies)

THIS blood test can detect deadly brain cancer in one hour. Here's how

<p>British writer Sophie Kinsella, the author of the popular book series ''Shopaholic'', has been diagnosed with a rare form of brain cancer. Kinsella shared the news on her Instagram.</p>

<p>On April 17, Kinsella shared on Instagram that she was suffering from glioblastoma, a rare form of terminal cancer.</p>

<p>In the statement shared on her social media handles, the 54-year-old writer said that she was diagnosed with a deadly disease at the end of 2022, and currently she's receiving chemotherapy and radiotherapy.</p>

<p><a href="https://www.wionews.com/entertainment/hollywood/news-the-directors-guild-of-america-sets-date-for-2025-awards-712790">The Directors Guild of America sets date for 2025 awards</a></p>

<p>Kinsella, whose real name is Madeleine Sophie Wickham, said, "At the end of 2022 I was diagnosed with glioblastoma, a form of aggressive brain cancer.''</p>

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<p>"I did not share this before because I wanted to make sure that my children were able to hear and process the news in privacy and adapt to our 'new normal. I have been under the care of the excellent team at University College Hospital in London and have had successful surgery and subsequent radiotherapy and chemotherapy, which is still ongoing."</p>

<p>Concluding her message, Sophie sent love to all those suffering from cancer and shared&nbsp;gratitude towards her readers for their ''wonderful response'' to her recently released book ''The Burnout''. ''It has really buoyed me up, during a difficult time,'' she said.&nbsp;</p>

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<p>Sophie is well-known for her eight-book ''Shopaholic'' series. The first two books of the series were adapted into the 2009 film <em>Confessions of a Shopaholic, </em>starring Isla Fisher.</p>

<p>Soon after Kinsella shared her cancer diagnosis,&nbsp;her fans and friends flooded the comment section with supporting and heartwarming&nbsp;messages.&nbsp;</p>

<p>Actress Isla wrote, ''Sending you so much love and healing energy.''</p>

<p>&nbsp;</p>

<p>An Instagram user wrote, ''As someone who has lived with a GBM4 for nearly 8 years in November, I'm sending so much love and strength to the next part of your journey ❤️❤️❤️.''</p>

<p>Kinsella shares five children with husband Henry Wickham.</p>

<p>Sophie has written over 25 books in her career, including&nbsp;bestselling books such as,&nbsp;''Can You Keep a Secret?'' (2003), ''The Undomestic Goddess'' (2005), ''Remember Me?'' (2008) ''Twenties Girl'' (2009).&nbsp;</p>

<p><strong>What is Glioblastoma?</strong></p>

<p>Glioblastoma is a rare form of cancerous tumour which develops in the brain from glial cells that provide support to neurons. It is a life-threatening disease.&nbsp;</p>

<p>The treatments for glioblastoma are surgery, radiotherapy and chemotherapy.</p>

<div class="videoWrapper trancodeVideo"><iframe allowfullscreen="" autoplay="1" class="includeVideo" frameborder="0" height="350" src="https://www.wionews.com/videos/cannes-film-festival-saudi-movie-gets-cannes-premiere-711592/embed" style="width:100%;max-width:560px;" width="560"></iframe></div>


British writer Sophie Kinsella, the author of the popular book series ''Shopaholic'', has been diagnosed with a rare form of brain cancer. Kinsella shared the news on her Instagram.

British writer Sophie Kinsella, the author of the popular book series ''Shopaholic'', has been diagnosed with a rare form of brain cancer. Kinsella shared the news on her Instagram. On April 17, Kinsella shared on Instagram that she was suffering from glioblastoma, a rare form of terminal cancer. In the statement shared on her social media handles, the 54-year-old writer said that she was diagnosed with a deadly disease at the end of 2022, and currently she's receiving chemotherapy and radiotherapy. The Directors Guild of America sets date for 2025 awards Kinsella, whose real name is Madeleine Sophie Wickham, said, "At the end of 2022 I was diagnosed with glioblastoma, a form of aggressive brain cancer.'' View this post on Instagram A post shared by Sophie Kinsella (@sophiekinsellawriter) × "I did not share this before because I wanted to make sure that my children were able to hear and process the news in privacy and adapt to our 'new normal. I have been under the care of the excellent team at University College Hospital in London and have had successful surgery and subsequent radiotherapy and chemotherapy, which is still ongoing." Concluding her message, Sophie sent love to all those suffering from cancer and shared gratitude towards her readers for their ''wonderful response'' to her recently released book ''The Burnout''. ''It has really buoyed me up, during a difficult time,'' she said. Daytime Emmy Awards 2024: Nominations out for June awards Sophie is well-known for her eight-book ''Shopaholic'' series. The first two books of the series were adapted into the 2009 film Confessions of a Shopaholic, starring Isla Fisher. Soon after Kinsella shared her cancer diagnosis, her fans and friends flooded the comment section with supporting and heartwarming messages. Actress Isla wrote, ''Sending you so much love and healing energy.'' An Instagram user wrote, ''As someone who has lived with a GBM4 for nearly 8 years in November, I'm sending so much love and strength to the next part of your journey ❤️❤️❤️.'' Kinsella shares five children with husband Henry Wickham. Sophie has written over 25 books in her career, including bestselling books such as, ''Can You Keep a Secret?'' (2003), ''The Undomestic Goddess'' (2005), ''Remember Me?'' (2008) ''Twenties Girl'' (2009). What is Glioblastoma? Glioblastoma is a rare form of cancerous tumour which develops in the brain from glial cells that provide support to neurons. It is a life-threatening disease. The treatments for glioblastoma are surgery, radiotherapy and chemotherapy.

Shopaholic author Sophie Kinsella reveals rare type of brain cancer diagnosis

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THIS blood test can detect deadly brain cancer in one hour. Here's how

Shopaholic author Sophie Kinsella reveals rare type of brain cancer diagnosis