The Food and Drug Administration (FDA) panel unanimously endorsed Lecanemab (Leqembi) to combat the progression of Alzheimer's. It is a breakthrough in Alzheimer's treatment.

The Food and Drug Administration (FDA) panel unanimously endorsed Lecanemab (Leqembi) to combat the progression of Alzheimer's. It is a breakthrough in Alzheimer's treatment. Experts called the clinical trial results of Lecanemab robust, clear, and consistent. It offers hope for 6.5 million individuals affected by Alzheimer's disease. However, the Centers for Medicare and Medicaid Services (CMS) have added a condition to Lecanemab's coverage, Hindustan Times reported. CMS will cover the drug for patients who join a national registry. Patients, doctors, and caretakers are concerned about the registration process and timeline. CMS's Coverage Criteria Alzheimer's Association has expressed their disagreement with the criteria implemented by CMS. According to them, it is unnecessary and could hinder patients' medical coverage. They believe that individuals with Alzheimer's disease should have unrestricted access to FDA-approved therapies, similar to patients with cancer, heart disease, and HIV/AIDS. The Alzheimer's Association believes these life-changing treatments must be available to all. The coverage delays and restrictions also have financial implications. Despite the CMS's reservations, the Department of Veterans Affairs (VA) will provide lecanemab for patients within the VA system. More about lecanemab In clinical trials, lecanemab showed a 27 per cent slower decline in cognitive abilities among individuals with mild cognitive impairment or Alzheimer's dementia. The drug also demonstrated the potential to increase the capability of patients to perform tasks like dressing and feeding themselves. Side effects of lecanemab The side effects of lecanemab include infusion site reactions and amyloid-related imagining abnormalities (ARIA), characterised by swelling in the brain. According to lecanemab's current label, doctors must monitor patients using MRI imagery to detect signs of ARIA. Unfortunately, Alzheimer's disease has no cure till now. Its advanced stages can lead to severe brain function loss, dehydration, malnutrition, and fatal infections. Lecanemab is not a cure for Alzheimer's disease. But it is an FDA-approved treatment that changes the course of the disease for people in the early stages. According to reports, manufacturers of lecanemab set the price at $26,500 a year. ALSO READ | NASA detects brightest gamma-ray burst of all time, it's 70 times brighter than previous record holder Lecanemab is appropriate for people with early Alzheimer's with diagnosed elevated beta-amyloid. According to the Alzheimer's Association, researchers tested the drug on people living with early Alzheimer's dementia and MCI due to Alzheimer's. These patients have a buildup of beta-amyloid plaques in the brain. However, people with more advanced stages of Alzheimer's or those without clinical symptoms did not participate in the clinical trials. Thus, there's no evidence of whether lecanemab would work on patients with a more complicated case of Alzheimer's. (With inputs from agencies) WATCH WION LIVE HERE

FDA-approved drug Lecanemab becomes hope for millions of Alzheimer's patients

Nepal gave emergency authorisation to India’s COVID-19 vaccine COVAXIN, becoming the third country to approve the shot.

COVID-19: Nepal gives an emergency nod to India's COVAXIN

Colombians are cautiously awaiting a peace deal in the South American nation after Bogota and the Revolutionary Armed Forces of Colombia (FARC) announced an agreement on a bilateral ceasefire and the end to hostilities at peace talks in Cuba on Wednesday. 
 
Authorities said the formal accord on the point will be signed today by President Juan Manuel Santos and FARC rebel leader Rodrigo Londono, better known by his nom de guerre Timochenko. 
 
&quot;It&#39;s always something important when it becomes concrete because there are a lot of doubts about what was really agreed in Havana and which hasn&#39;t yet surfaced. Citizens still don&#39;t know (about the peace agreement). We all want peace and hopefully this (deal) is good,&quot; said citizen, Terencio Poo. 
 
Agreement on a third point of the negotiating agenda would be a major step forward in efforts by the two sides to end 50 years of war that have killed 220,000 people and displaced millions. 
 
Santos has promised the final accord will be put to the Colombian people in a plebiscite, and must win over those sceptical of FARC promises to rejoin civil society, including supporters of hard-line former President Alvaro Uribe who claims a deal will grant guerrillas impunity for war crimes. 
 
&quot;Hopefully the announcement tomorrow tells us that there will be jail for those who have committed heinous crimes and crimes against humanity,&quot; said co-President of the Democratic Centre opposition party, Oscar Ivan Zuluaga, 
 
Once there is agreement on the third agenda point, the only remaining topic is how exactly the referendum will be organised. 
If approved by the public, it would bring to an end Latin America&#39;s longest armed conflict. 
 
&quot;There are a lot generations, like mine, who never seen a single day of peace and tomorrow will be practically the end of the war,&quot; said Senator Mauricio Lizcano from Santos` ruling party. 
 
President Santos has said this week the government and the rebels will complete negotiations for a final deal by July 20. The ceasefire, which includes terms for the FARC&#39;s demobilisation, laying down of arms, and security for former fighters, does not begin until the final deal is signed. 
 
Colombian citizen Mariana Hoyos said Wednesday&#39;s ceasefire announcement is the first of many steps of a peace to come. 
&quot;This is the first step and I think there is still a lot to be done, but this is the start,&quot; she said. 
 
Cuban President Raul Castro, United Nations Secretary-General Ban Ki-moon, Venezuelan President Nicolas Maduro and Chilean President Michelle Bachelet are also expected to attend the signing ceremony in Havana the two sides said.&nbsp; 
 
(Reuters)

If approved, it would bring to an end Latin America's longest armed conflict

Colombians are cautiously awaiting a peace deal in the South American nation after Bogota and the Revolutionary Armed Forces of Colombia (FARC) announced an agreement on a bilateral ceasefire and the end to hostilities at peace talks in Cuba on Wednesday. Authorities said the formal accord on the point will be signed today by President Juan Manuel Santos and FARC rebel leader Rodrigo Londono, better known by his nom de guerre Timochenko. "It's always something important when it becomes concrete because there are a lot of doubts about what was really agreed in Havana and which hasn't yet surfaced. Citizens still don't know (about the peace agreement). We all want peace and hopefully this (deal) is good," said citizen, Terencio Poo. Agreement on a third point of the negotiating agenda would be a major step forward in efforts by the two sides to end 50 years of war that have killed 220,000 people and displaced millions. Santos has promised the final accord will be put to the Colombian people in a plebiscite, and must win over those sceptical of FARC promises to rejoin civil society, including supporters of hard-line former President Alvaro Uribe who claims a deal will grant guerrillas impunity for war crimes. "Hopefully the announcement tomorrow tells us that there will be jail for those who have committed heinous crimes and crimes against humanity," said co-President of the Democratic Centre opposition party, Oscar Ivan Zuluaga, Once there is agreement on the third agenda point, the only remaining topic is how exactly the referendum will be organised. If approved by the public, it would bring to an end Latin America's longest armed conflict. "There are a lot generations, like mine, who never seen a single day of peace and tomorrow will be practically the end of the war," said Senator Mauricio Lizcano from Santos` ruling party. President Santos has said this week the government and the rebels will complete negotiations for a final deal by July 20. The ceasefire, which includes terms for the FARC's demobilisation, laying down of arms, and security for former fighters, does not begin until the final deal is signed. Colombian citizen Mariana Hoyos said Wednesday's ceasefire announcement is the first of many steps of a peace to come. "This is the first step and I think there is still a lot to be done, but this is the start," she said. Cuban President Raul Castro, United Nations Secretary-General Ban Ki-moon, Venezuelan President Nicolas Maduro and Chilean President Michelle Bachelet are also expected to attend the signing ceremony in Havana the two sides said. (Reuters)

Colombians cautiously optimistic about peace deal with FARC

approved

Approved, News on Approved, stories on Approved, articles on Approved, Approved stories at Wion, Approved news, Approved latest news