A recent report has revealed over 5,300 adverse events involving gabapentin in 2025, including a notable increase in cases linked to dementia and cognitive impairment. Multiple studies, including a large-scale analysis published in 2025, show that frequent or long-term use of gabapentin, especially for chronic pain-is associated with a significantly higher risk of dementia and mild cognitive impairment, particularly among adults aged 35 to 64.

Gabapentin Tied to Dementia: 5,300 Adverse Events Reported in 2025

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