<p>When does ageing start? Is it a gradual process or is there a specific age in which we start to 'suddenly' age? According to a new study, there are two, not one, time periods in our lives when we show sudden signs of ageing.</p>

<p>There is a burst of ageing at 44, and then at 60, accoriding to research done at Stanford University in the US.</p>

<p>This busts the general notion that our bodies and minds decline in a slow process, referred to as 'linear ageing'.</p>

<p><strong>Watch: China's anti-ageing component isolated from blood</strong><br />
&nbsp;</p>

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<p>Earlier, the ageing in 40s was seen as part of onset of menopause in women, but the study has shown that men also show signs of decline in mid-40s onwards.</p>

<h2><strong>How did they reach the conclusion?</strong></h2>

<p>The study published in Nature Ageing journal tracked thousands of different molecules in people aged between 25 and 75.</p>

<p>It found two waves of age-related changes in the molecular composition of bodies: at around ages 44 and again at 60.&nbsp;</p>

<p>The findings could explain "why spikes in certain health issues including musculoskeletal problems and cardiovascular disease occur at certain ages," the researchers said.</p>

<p><strong>Also read: <a href="https://www.wionews.com/science/new-study-reveals-that-your-bodys-cells-age-rapidly-within-a-day-719816">New study reveals that your body's cells age rapidly within a day</a></strong><br />
&nbsp;</p>

<p>The researchers call these sudden spurts 'nonlinear' ageing. "The analysis revealed consistent nonlinear patterns in molecular markers of ageing, with substantial dysregulation occurring at two major periods occurring at approximately 44 years and 60 years of chronological age," said the study.&nbsp;</p>

<p>They found cardiovascular disease, lipid and alcohol metabolism changes at the 40-year transition, and shifts in "immune regulation and carbohydrate metabolism" during the 60-year transition.</p>

<p><strong>Also read:&nbsp;<a href="https://www.wionews.com/science/study-shows-strong-links-between-losing-loved-ones-and-ageing-745671">Study shows 'strong links' between losing loved ones and biological ageing</a></strong></p>

<p>Risk of diseases accelerate at specific points in human lifespan.</p>

<p>The study pointed out that in the US,&nbsp; atherosclerosis, stroke and heart attacks are are up 40% between the ages of 40 and 59. It rises to about 75% between ages 60 and 79 and reaches &nbsp;86% at 80 years and above.</p>

<p>Neurodegenerative diseases like Parkinson’s and Alzheimer’s have distinct "turning points" around the ages of 40 and 65, respectively.</p>

<h2><strong>What is ageing?&nbsp;</strong></h2>

<p>Ageing is the decline in physical and cognitive abilities, as well as changes in&nbsp;appearance such as wrinkling skin. This is also the period in which people suffer from aches and pains, and diseases and wounds take longer to heal.</p>

<p>According to World Health Organization, ageing is on the rise globally.</p>

<p>"In 2019, the number of people aged 60 years and older was 1 billion. This number will increase to 1.4 billion by 2030 and 2.1 billion by 2050," it says on its Ageing website.&nbsp;</p>

<p><em>(With inputs from agencies)</em></p>


When does ageing start? Is it a gradual process or is there a specific age in which we start to 'suddenly' age? According to a new study, there are two, not one, time periods in our lives when we show sudden signs of ageing.

When does ageing start? Is it a gradual process or is there a specific age in which we start to 'suddenly' age? According to a new study, there are two, not one, time periods in our lives when we show sudden signs of ageing. There is a burst of ageing at 44, and then at 60, accoriding to research done at Stanford University in the US. This busts the general notion that our bodies and minds decline in a slow process, referred to as 'linear ageing'. Watch: China's anti-ageing component isolated from blood × Earlier, the ageing in 40s was seen as part of onset of menopause in women, but the study has shown that men also show signs of decline in mid-40s onwards. How did they reach the conclusion? The study published in Nature Ageing journal tracked thousands of different molecules in people aged between 25 and 75. It found two waves of age-related changes in the molecular composition of bodies: at around ages 44 and again at 60. The findings could explain "why spikes in certain health issues including musculoskeletal problems and cardiovascular disease occur at certain ages," the researchers said. Also read: New study reveals that your body's cells age rapidly within a day The researchers call these sudden spurts 'nonlinear' ageing. "The analysis revealed consistent nonlinear patterns in molecular markers of ageing, with substantial dysregulation occurring at two major periods occurring at approximately 44 years and 60 years of chronological age," said the study. They found cardiovascular disease, lipid and alcohol metabolism changes at the 40-year transition, and shifts in "immune regulation and carbohydrate metabolism" during the 60-year transition. Also read: Study shows 'strong links' between losing loved ones and biological ageing Risk of diseases accelerate at specific points in human lifespan. The study pointed out that in the US, atherosclerosis, stroke and heart attacks are are up 40% between the ages of 40 and 59. It rises to about 75% between ages 60 and 79 and reaches 86% at 80 years and above. Neurodegenerative diseases like Parkinson’s and Alzheimer’s have distinct "turning points" around the ages of 40 and 65, respectively. What is ageing? Ageing is the decline in physical and cognitive abilities, as well as changes in appearance such as wrinkling skin. This is also the period in which people suffer from aches and pains, and diseases and wounds take longer to heal. According to World Health Organization, ageing is on the rise globally. "In 2019, the number of people aged 60 years and older was 1 billion. This number will increase to 1.4 billion by 2030 and 2.1 billion by 2050," it says on its Ageing website. (With inputs from agencies)

When does ageing really kick in? Scientists find two specific ages when signs show up. They are...

<p>Ageing underlines the fatalist truth about being human. But scientists around the world are working on ways to stop, or at least slowing down the process. An increasing number of scientists believe that a treatment for Type 2 diabetes may help in slowing down ageing, The Washington Post first reported.</p>

<p>The treatment called "metformin" is helpful is reportedly slowing down multiple age-related ailments, including heart disease, dementia, and cancer.&nbsp;</p>

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<p>If true, metformin can not just fight these diseases, but also potentially extend our lifespan. But immortality is still light years away!</p>

<p>Nir Barzilai, Director of the Institute for Aging Research, Albert Einstein College of Medicine told the Washington Post that they haven't found the "fountain of youth", but instead claim to delay ageing.</p>

<p>A group of scientists met in Spain in 2014 to find ways to counter ageing. In the aftermath of this meeting, a six-year clinical trial called "Targeting Aging with Metformin" (TAME) was proposed.&nbsp;</p>

<p><strong>Also read:&nbsp;</strong><a href="http://13.235.153.162/science/israeli-scientists-go-backward-in-time-by-successfully-reversing-ageing-by-25-years-344816" hreflang="en">Israeli scientists go 'backward in time' by successfully reversing ageing by 25 years</a></p>

<p>The trial intends to dig deeper into the anti-ageing techniques of metformin, and will involve at least 3,000 subjects aged between 65-79. It will take place across 14 research sites situated in universities spread across the US, TAME's website claims.</p>

<p>Scientists took up TAME after seeing encouraging results involving metformin. The study is currently in its infancy stage, with more research expected to shed light on the role of metformin in delaying ageing.</p>

<p><strong>Also read:</strong>&nbsp;<a href="http://13.235.153.162/world/regular-intake-of-junk-food-can-affect-chromosomes-related-to-ageing-study-324492" hreflang="en">Regular intake of junk food can affect chromosomes related to ageing: Study</a><br />
<br />
Earlier, Israeli scientists claimed they had also reversed signs of ageing. Scientists at Tel Aviv University and the Shamir Medical Center claimed to have not only stop ageing, but to reverse it by administering oxygen at high-pressure levels in a chamber. &nbsp;According to Al Jazeera, it reversed two processes associated with ageing and illness</p>


Ageing underlines the fatalist truth about being human. But scientists around the world are working on ways to stop, or at least slowing down the process. An increasing number of scientists believe that a treatment for Type 2 diabetes may help in slowing down ageing, The Washington Post first reported.

Ageing underlines the fatalist truth about being human. But scientists around the world are working on ways to stop, or at least slowing down the process. An increasing number of scientists believe that a treatment for Type 2 diabetes may help in slowing down ageing, The Washington Post first reported. The treatment called "metformin" is helpful is reportedly slowing down multiple age-related ailments, including heart disease, dementia, and cancer. If true, metformin can not just fight these diseases, but also potentially extend our lifespan. But immortality is still light years away! Nir Barzilai, Director of the Institute for Aging Research, Albert Einstein College of Medicine told the Washington Post that they haven't found the "fountain of youth", but instead claim to delay ageing. A group of scientists met in Spain in 2014 to find ways to counter ageing. In the aftermath of this meeting, a six-year clinical trial called "Targeting Aging with Metformin" (TAME) was proposed. Also read: Israeli scientists go 'backward in time' by successfully reversing ageing by 25 years The trial intends to dig deeper into the anti-ageing techniques of metformin, and will involve at least 3,000 subjects aged between 65-79. It will take place across 14 research sites situated in universities spread across the US, TAME's website claims. Scientists took up TAME after seeing encouraging results involving metformin. The study is currently in its infancy stage, with more research expected to shed light on the role of metformin in delaying ageing. Also read: Regular intake of junk food can affect chromosomes related to ageing: Study Earlier, Israeli scientists claimed they had also reversed signs of ageing. Scientists at Tel Aviv University and the Shamir Medical Center claimed to have not only stop ageing, but to reverse it by administering oxygen at high-pressure levels in a chamber. According to Al Jazeera, it reversed two processes associated with ageing and illness

This diabetes treatment can delay ageing among humans, scientists claim

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ageing processes

When does ageing really kick in? Scientists find two specific ages when signs show up. They are...

This diabetes treatment can delay ageing among humans, scientists claim