At least 16 civilians were killed and dozens wounded on Saturday in an air strike on a rebel-held area outside Syria's capital Damascus, the Syrian Observatory for Human Rights monitor said.
At least 16 people were also killed overnight in air strikes on a prison in the rebel-held city of Idlib in northwest Syria, the monitor said earlier.
It said the dead included prisoners and prison guards, but did not have an immediate breakdown of the toll.
The strikes were believed to have been carried out by Russian warplanes, which have been flying sorties in support of President Bashar al-Assad's government since Moscow began a military intervention in September 2015.
It said it was not immediately clear who was responsible for the strike on the town Hammuriyeh in the opposition bastion of Eastern Ghouta.
"Sixteen civilians, including a child, were killed and around 50 others wounded in an air strike on the main street in the town of Hammuriyeh," Observatory director Rami Abdel Rahman said.
It was not immediately clear if all the wounded were civilians or if some were rebel fighters, he said, adding that the death toll could rise further because a number of the injured were in serious condition.
The Eastern Ghouta region outside Damascus has been under a devastating government siege since 2012, and is also the regular target of regime air strikes and artillery fire.
It is the last remaining opposition stronghold near Damascus, where a string of local "reconciliation deals" have seen villages and towns brought back under the control of President Bashar al-Assad's government.
More than 320,000 people have been killed in Syria since the conflict began in March 2011 with anti-government protests.
Government ally Russia and rebel backer Turkey brokered a nationwide truce in December, but violence has continued across the country.