Britain won the world 4x100m relay on Saturday
Hopes were high for Bolt's final competitive race, with Jamaica also boasting McLeod, Forte and 2011 world champion Yohan Blake in their line-up.
Jamaica were afforded a rousing welcome from the crowd, a relaxed-looking Bolt applauding the stands, with pictures of him constantly shown on the stadium's big screens.
Tyquendo Tracey, Julian Forte and Michael Campbell safely negotiated the first three legs before Bolt steered his team home in a winning, season's best of 37.95 seconds.
"It's been brilliant. The energy in the stadium is outstanding," Bolt said, hailing the deafening support in the packed-out London Stadium "not just for me but the whole championships".